Archive for the ‘DNA’ category: Page 8
Jul 7, 2018
Bioquark Inc. — Funky Thinkers Podcast — Ira Pastor
Posted by Ira S. Pastor in categories: aging, bioengineering, biological, biotech/medical, DNA, futurism, genetics, health, life extension, transhumanism
Jun 17, 2018
Harvard Rewinds the Biological Clock of Time
Posted by Nicholi Avery in categories: bioengineering, biological, DNA, health, life extension, science, transhumanism
Investigators at Harvard Medical School have identified the key cellular mechanisms behind vascular aging and its effects on muscle health, and they have successfully reversed the process in animals.
The scientists used a chemical compound that’s an NAD+ booster called NMN which plays a critical role in repairing cellular DNA as well as maintaining cell vitality to test what would happen.
Could reversing the aging of blood vessels hold the key to restoring youthful vitality? If the old adage “you are as old as your arteries” reigns true then the answer is yes, at least in mice.
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Jun 11, 2018
Bioquark Inc. — “Living Forever” — Future Sandwich Podcast — Ira Pastor
Posted by Ira S. Pastor in categories: aging, bioengineering, biotech/medical, cryonics, DNA, futurism, genetics, health, life extension, Peter Diamandis
Jun 9, 2018
Human Skeletal Muscle Aging and Mutagenesis
Posted by Nicholi Avery in categories: aging, DNA, genetics, health, life extension
Study based upon human skeletal muscle aging, mutagenesis, and the role of #satellite cells.
“A more comprehensive understanding of the interplay of stem cell–intrinsic and extrinsic factors will set the stage for improving cell therapies capable of restoring tissue homeostasis and enhancing muscle repair in the aged.”
Human aging has multiple effects on the human body. One of the effects of human aging is the reduction in skeletal muscle (SkM) function and a reduction in the number and activity of satellite cells (SCs), the resident stem cells. The whole genome of single SC clones of the leg muscle vastus lateralis from healthy individuals of different ages (21–78 years) was analyzed, to study the specific connection between SC aging and muscle impairment. In healthy adult muscle rapid increase of SCs is consistent with the accumulation rate of 13 somatic mutations per genome per year. Mutations typically do not happen in SkM-expressed genes because they are protected. However, as mutations in exons and promoters increase, genes involved in SC activity and muscle function are targeted which results in aging. Exons are coding sections of an RNA transcript, or the DNA encoding it, that are translated into protein. Proteins are the synthesis of molecules. A change in of a single base pair that caused the substitution of a different amino acid in the resulting protein (missense mutation) that was propagated to the muscle and detected in association with SC mutations affecting the whole tissue. #Somatic mutagenesis in SCs as a result is the driving force in the age related decline of SkM function.
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Jun 5, 2018
Can You Actually Hack Your DNA to Slow Down Aging? — Bioquark Inc. — Ira Pastor
Posted by Ira S. Pastor in categories: aging, biotech/medical, DNA, genetics, health, innovation, life extension, neuroscience, science, transhumanism
http://www.thepathmag.com/can-you-actually-hack-your-dna-to-slow-down-aging/
Many technologies / interventions progressing down the development pathways in the coming years — but there are a lot of free, common sense adjustments you can make today:
Jun 5, 2018
Bioquark Inc. — Healthy Relationship Talk Radio — Ira Pastor
Posted by Ira S. Pastor in categories: aging, bioengineering, biotech/medical, cryonics, disruptive technology, DNA, futurism, genetics, health, life extension
Jun 5, 2018
Bioquark Inc. — Free Your Mind Podcast — Ira Pastor
Posted by Ira S. Pastor in categories: aging, biotech/medical, business, DNA, education, finance, futurism, health, life extension, neuroscience
May 22, 2018
Bioquark Inc. — Enterprise NOW! Podcast — Ira Pastor
Posted by Ira S. Pastor in categories: aging, bioengineering, biotech/medical, business, disruptive technology, DNA, economics, finance, futurism, genetics
May 17, 2018
Selfish Ledger: Google’s mass sociology experiment
Posted by Philip Raymond in categories: big data, complex systems, DNA, ethics, evolution, genetics, information science, internet, surveillance
Check out the internal Google film, “The Selfish Ledger”. This probably wasn’t meant to slip onto a public web server, and so I have embedded a backup copy below. Ping me if it disappears. I will locate a permanent URL.
This 8½ minute video is a lot deeper—and possibly more insipid—than it appears. Nick Foster may be the Anti-Christ, or perhaps the most brilliant sociologist of modern times. It depends on your vantage point, and your belief in the potential of user controls and cat-in-bag containment.
He talks of a species propelling itself toward “desirable goals” by cataloging, data mining, and analyzing the past behavior of peers and ancestors—and then using that data to improve the experience of each user’s future and perhaps even their future generations. But, is he referring to shared goals across cultures, sexes and incomes? Who controls the algorithms and the goal filters?! Is Google the judge, arbiter and God?
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