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Category: chemistry – Page 311

Dr. John Torday, Ph.D. is an Investigator at The Lundquist Institute of Biomedical Innovation, a Professor of Pediatrics and Obstetrics/Gynecology, and Faculty, Evolutionary Medicine, at the David Geffen School of Medicine at UCLA, and Director of the Perinatal Research Training Program, the Guenther Laboratory for Cell-Molecular Biology, and Faculty in the Division of Neonatology, at Harbor-UCLA Medical Center.

Dr. Torday studies the cellular-molecular development of the lung and other visceral organs, and using the well-established principles of cell-cell communication as the basis for determining the patterns of physiologic development, his laboratory was the first to determine the complete repertoire of lung alveolar morphogenesis. This highly regulated structure offered the opportunity to trace the evolution of the lung from its unicellular origins forward, developmentally and phylogenetically. The lung is an algorithm for understanding the evolution of other physiologic properties, such as in the kidney, skin, liver, gut, and central nervous system. Such basic knowledge of the how and why of physiologic evolution is useful in the effective diagnosis and treatment of disease.

Dr. Torday received his undergraduate degree in Biology and English from Boston University, and his MSc and PhD in Experimental Medicine from McGill University, Montreal, Canada. He did a post-doctoral Fellowship in Reproductive Endocrinology at the University of Wisconsin-Madison, WI.

Dr. Torday’s research has led to the publication of more than 150 peer-reviewed articles and 350 abstracts. More recently, he has gained an interest in the evolutionary aspects of comparative physiology and development, leading to the publication of 12 peer-reviewed articles on the cellular origins of vertebrate physiology, culminating in the book Evolutionary Biology, Cell-Cell Communication and Complex Disease.

Dr. Torday is also the co-author / co-editor on several volumes including: Evolution, the Logic of Biology, Evidence-Based Evolutionary Medicine, Morphogenesis, Environmental Stress and Reverse Evolution, and most recently, The Singularity of Nature: A Convergence of Biology, Chemistry and Physics.

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In the search for ways to effectively combat age-related human disease, the enzyme sirtuin 6 (Sirt6) has recently become a focus of biochemical research. A targeted activation of Sirt6 could prevent or mitigate such diseases, for example some types of cancer. In a paper for the journal Nature Chemical Biology, biochemists from the University of Bayreuth have now shown how the small molecule MDL-801 binds to the enzyme Sirt6 and influences its activity. These findings stand to aid the development of new drugs.

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A team of researchers from the University of Science and Technology of China, the Chinese Academy of Sciences and the Southern University of Science and Technology, has discovered a thought-provoking pattern in cross-sections observed in an F + HD → HF + D reaction. In their paper published in the journal Science, the group describes their double-pronged approach to learning more about the role of relativistic spin-orbit interactions in chemical reactions. T. Peter Rakitzis, with the University of Crete, and IESL-FORTH, has published a Perspectives piece in the same journal issue outlining the difficulty of studying chemical reactions at the quantum level and the work done by the team in China.

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Innovative silicon solutions provider HPQ Silicon Resources Inc. (“HPQ” or the “Company”), announced that it has received the TREKHY® system, a portable hydrogen-based mini-power generator, jointly developed by the French companies Apollon Solar SAS (“Apollon”) and Pragma Industries SAS (“Pragma”).

While continuing to work with Apollon on the development of new generations of more efficient silicon powders for hydrogen production, HPQ signed a Memorandum of Understanding with Apollon and Pragma to study the commercial potential of the TREKHY® autonomous power generator in Canada.

The TREKHY® provides energy on demand. The system uses a compact fuel cell to provide electrical power. The integrated fuel cell combines hydrogen and oxygen to provide useful electricity + H2O. Hydrogen is produced through a chemical reaction resulting from contact between water and a powder bag. Each bag delivers 30W of power for more than one hour. (Video of the system in operation). In January 2021, a Japanese distributor purchased 300 TREKHY® systems to equip the survival shelters of the Japanese Civil Security.

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“Scientists found that a caterpillar called the tomato fruit worm not only chomps on tomatoes and their leaves, but also deposits enzyme-laden saliva on the plant, interfering with its ability to cry for help. If it all sounds a bit improbable, starting with the concept of plants crying for help, scientists also scoffed at that idea when it was first proposed a few decades ago. But it has been shown time and time again that when under attack, plants can emit chemical distress signals, causing their peers to mount some sort of defense. A classic example is the smell of a freshly mown lawn, which prompts the release of protective compounds in nearby blades of grass that have yet to be cut. In some cases, plant distress signals can even summon help from other species. That’s what happens with the tomato. When caterpillars nibble on the plant’s leaves, the leaf pores release volatile chemicals that are detected by a type of parasite: a wasp that lays eggs inside caterpillars. (Not to overwork the horror-movie analogy, but as with the hapless astronauts in the “Aliens” franchise, it doesn’t end well for the caterpillar.)”

While there’s a famous horror-movie spoof about killer tomatoes, no one seems to have made one about caterpillars—the insect pests that eat the juicy red fruits of summer.

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Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and heart rate while measuring the wearer’s levels of glucose as well as lactate, alcohol, or caffeine. It is the first wearable device that monitors cardiovascular signals and multiple biochemical levels in the human body at the same time.

“This type of wearable would be very helpful for people with underlying medical conditions to monitor their own health on a regular basis,” said Lu Yin, a nanoengineering Ph.D. student at UC San Diego and co-first author of the study published on February 152021, in Nature Biomedical Engineering. “It would also serve as a great tool for remote patient monitoring, especially during the COVID-19 pandemic when people are minimizing in-person visits to the clinic.”

Such a device could benefit individuals managing high blood pressure and diabetes — individuals who are also at high risk of becoming seriously ill with COVID-19. It could also be used to detect the onset of sepsis, which is characterized by a sudden drop in blood pressure accompanied by a rapid rise in lactate level.

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When a leafy plant is under attack, it doesn’t sit quietly. Back in 1983, two scientists, Jack Schultz and Ian Baldwin, reported that young maple saplings getting bitten by insects release a spurt of chemicals that float through the air. You and I wouldn’t notice, but these chemicals carry a slight odor that neighboring plants can detect. It’s a little like a silent scream.

These chemicals come from the injured parts of the plant and seem to be an alarm. Maybe not an intentional warning like, “Watch Out! Aphid Attack!” but more like a simple distress call like, “Aphids! Aphids! Aphids!” or, “Attack! Attack!” The chemicals the plants pump through the air are a blend of organic molecules — alcohols, aldehydes, ketones and esters — known as volatile organic compounds, VOCs for short.”

Animals bark, sing, growl and chat. Plants, one would think, just sit there. But it turns out that plants bark, growl and chat as well. Here’s how they do it.

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Engineers at the University of California San Diego have developed a soft, stretchy skin patch that can be worn on the neck to continuously track blood pressure and heart rate while measuring the wearer’s levels of glucose as well as lactate, alcohol or caffeine. It is the first wearable device that monitors cardiovascular signals and multiple biochemical levels in the human body at the same time.

Read more | >

Researchers unlocked the electronic properties of graphene by folding the material like origami paper.

Researchers at Monash University’s Department of Chemical Engineering, IITB-Monash Research Academy Mumbai, and The Indian Institute of Technology’s Department of Chemical Engineering have used reactive flash volatilisation (RFV) gasification technology to produce hydrogen using microalgae, giving rise to newer and cleaner forms of energy.

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