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Category: chemistry – Page 251

A team of researchers from Nanjing University of Posts and Telecommunications and the Chinese Academy of Sciences in China and Nanyang Technological University and the Agency for Science Technology and Research in Singapore developed an artificial neuron that is able to communicate using the neurotransmitter dopamine. They published their creation and expected uses for it in the journal Nature Electronics.

As the researchers note, most machine-brain interfaces rely on as a communications medium, and those signals are generally one-way. Electrical signals generated by the brain are read and interpreted; signals are not sent to the brain. In this new effort, the researchers have taken a step toward making a that can communicate in both directions, and it is not based on electrical signals. Instead, it is chemically mediated.

The work involved building an artificial neuron that could both detect the presence of dopamine and also produce dopamine as a response mechanism. The neuron is made of graphene (a single sheet of carbon atoms) and a carbon nanotube electrode (a single sheet of carbon atoms rolled up into a tube). They then added a sensor capable of detecting the presence of dopamine and a device called a memristor that is capable of releasing dopamine using a heat-activated hydrogel, attached to another part of their artificial neuron.

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It’s “a revolutionary scientific advance in molecular data storage and cryptography.”

Scientists from the University of Texas at Austin sent a letter to colleagues in Massachusetts with a secret message: an encryption key to unlock a text file of L. Frank Baum’s classic novel The Wonderful Wizard of Oz. The twist: The encryption key was hidden in a special ink laced with polymers, They described their work in a recent paper published in the journal ACS Central Science.

When it comes to alternative means for data storage and retrieval, the goal is to store data in the smallest amount of space in a durable and readable format. Among polymers, DNA has long been the front runner in that regard. As we’ve reported previously, DNA has four chemical building blocks—adenine (A), thymine (T), guanine (G), and cytosine ©—which constitute a type of code. Information can be stored in DNA by converting the data from binary code to a base-4 code and assigning it one of the four letters. A single gram of DNA can represent nearly 1 billion terabytes (1 zettabyte) of data. And the stored data can be preserved for long periods—decades, or even centuries.

There have been some inventive twists on the basic method for DNA storage in recent years. For instance, in 2019, scientists successfully fabricated a 3D-printed version of the Stanford bunny—a common test model in 3D computer graphics—that stored the printing instructions to reproduce the bunny. The bunny holds about 100 kilobytes of data, thanks to the addition of DNA-containing nanobeads to the plastic used to 3D print it. And scientists at the University of Washington recently recorded K-Pop lyrics directly onto living cells using a “DNA typewriter.”

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Science, Technology, Health, Physics, Chemistry stay Updated.

Scientists from The Australian National University (ANU) and James Cook University (JCU) have identified an “exquisite” natural mechanism that helps plants limit their water loss with little effect on carbon dioxide (CO2) intake—an essential process for photosynthesis, plant growth and crop yield.

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• Earth.com

A new study led by Michigan State University (MSU) has found that locusts can reliably detect through smell a variety of human cancers. The insects can not only “smell” the difference between healthy and cancerous cells, but they can also distinguish between different cancer cell lines. These findings could provide a basis for devices which use locust sensory neurons to enable the early detection of cancer by using only biomarkers in a patient’s breath.

“Noses are still state of the art,” said study senior author Debajit Saha, an assistant professor of Biomedical Engineering at MSU. “There’s really nothing like them when it comes to gas sensing. People have been working on ‘electronic noses’ for more than 15 years, but they’re still not close to achieving what biology can do seamlessly.”

Cancer cells function differently from healthy ones, and create different chemical compounds as they grow. If these chemicals reach the lungs or airways – which happens in most types of cancer – they can be detected in exhaled breath. “Theoretically, you could breathe into a device, and it would be able to detect and differentiate multiple cancer types and even which stage the disease is in. However, such a device isn’t yet close to being used in a clinical setting,” Professor Saha explained.

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Archived histological material from tracing studies, immunohistochemistry, and Golgi impregnations allowed to discover a so far unrecognized structural difference, potentially of functional importance, between neocortical pyramidal neurons of rodent, carnivore, and ungulate as compared to monkey and man.

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The challenge: The building and construction sector is responsible for a big chunk of global carbon emissions. A lot of those emissions come from the production of cement, which is the second most consumed material on the planet behind water.

Cement produces emissions in two main ways. One is through the chemical reactions that occur while sintering limestone and other materials to make “clinker,” a key component of cement. The other comes from using fossil fuels to heat up kilns to very high temperatures.

Cement production releases massive amounts of carbon dioxide, other greenhouse gasses, and particulate emissions into the atmosphere. But it results in the world’s most widely used building material: concrete. Cheap, familiar, and reliable, concrete will likely remain the construction industry’s preferred material for years to come.

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Do more pores in a sieve allow more liquid to flow through it? As material scientists have uncovered, this seemingly simple question may have an unexpected answer at the nanoscale—and it could have important implications in the development of water filtration, energy storage and hydrogen production.

Researchers from UNSW Sydney, University of Duisburg-Essen (Germany), GANIL (France) and Toyota Technological Institute (Japan) experimenting with Graphene Oxide (GO) membranes have discovered the opposite can occur at the nanoscopic level. The research, published in Nano Letters, shows the chemical environment of the sieve and the of the liquid play a surprisingly important role in permeability.

The researchers observed that a density of pores doesn’t necessarily lead to higher permeability—in other words, having more tiny holes doesn’t always allow water to flow through at the nanoscale. The study, supported by the European Union and Humboldt Research Foundation funding, shines new light on the mechanisms that govern water flow through GO membranes.

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A Purdue University chemical engineer has improved upon traditional methods to produce off-the-shelf human immune cells that show strong antitumor activity, according to a paper published in the peer-reviewed journal Cell Reports.

Xiaoping Bao, a Purdue University assistant professor from the Davidson School of Chemical Engineering, said CAR-neutrophils, or chimeric antigen receptor neutrophils, and engraftable HSCs, or , are effective types of therapies for blood diseases and cancer. Neutrophils are the most abundant white cell blood type and effectively cross physiological barriers to infiltrate solid tumors. HSCs are specific progenitor that will replenish all blood lineages, including neutrophils, throughout life.

“These cells are not readily available for broad clinical or research use because of the difficulty to expand ex vivo to a sufficient number required for infusion after isolation from donors,” Bao said. “Primary neutrophils especially are resistant to genetic modification and have a short half-life.”

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Within minutes of the final heartbeat, a cascade of biochemical events triggered by a lack of blood flow, oxygen, and nutrients begins to destroy a body’s cells and organs. But a team of Yale scientists has found that massive and permanent cellular failure doesn’t have to happen so quickly.

The researchers stressed that additional studies are necessary to understand the apparently restored motor functions in the animals, and that rigorous ethical review from other scientists and bioethicists is required.

The experimental protocols for the latest study were approved by Yale’s Institutional Animal Care and Use Committee and guided by an external advisory and ethics committee.

The OrganEx technology could eventually have several potential applications, the authors said. For instance, it could extend the life of organs in human patients and expand the availability of donor organs for transplant. It might also be able to help treat organs or tissue damaged by ischemia during heart attacks or strokes.

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