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Category: chemistry – Page 217

Lengthening Telomeres To Rewind the Clock of Aging

Haven’t heard from Bill Andrews in awhile.

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Here we talk with Dr Bill Andrews all about telomeres, why they are on the critical path of aging and finding a way to lengthen them is required in an complete longevity solution.
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⏲️Chapters.
00:00 Why telomeres.
07:10 Telomeres and aging.
14:36 Telomerase in stem cells.
20:15 BiOptimizers.
21:44 Telomere shortening.
23:25 Measuring telomere length.
25:30 Biological age.
30:30 Slowing telomere shortening.
39:30 Supplements to help.
41:30 Sierra Science Chemicals \& Gene therapy.
49:30 How is telomerase repressed.
56:10 Liz Parrish \& Gene therapy.
1:01:40 Gene therapy delivery.
1:09:20 Telomerase \& cancer.
1:17:00 Why aging.
1:20:30 Telomeres \& senescence.
1:24:30 More information.

🌐Links in this video.

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Cannabidiol for musculoskeletal regenerative medicine

It is well-established that chronic MSK pain is the key factor for physical disability in the adult population. 19 The World Health Organization (WHO) estimates that 20–33% (over 1.71 billion individuals) of the global population suffers from chronic MSK pain. 20 This type of disorder is characterized by acute or chronic pain in MSK structures, which involve muscles, tendons, ligaments, bones, and nerves. 21 The most common conditions responsible for visits to a physician’s office are OA, rheumatoid arthritis, myofascial pain syndrome (MPS), and low back and neck pain. 22 Less common incidents are generally accompanying with injuries like of tendon sprains, ligament tears, muscle tears, fractures, and similar damage during sports. 20

If left untreated, these conditions progressively increase suffering, disability, and drug consumption, which subsequently diminish an individual’s quality of life. 23 This also translates to a main community health problem due to significant high expenses for health-care systems and insurance for disability. Advanced age may remain the top variable associated with the increased risk of musculoskeletal disorders (MSDs) and MSK pain; however, these conditions may still unfold at any given age for various reasons. Therefore, every individual is at risk of experiencing MSK pain throughout an entire lifetime. 24 Acute pain can become chronic due to numerous factors. The level of intensity, site, and time of noxious stimuli are dictated by the interplay between mechanical, chemical, and thermal receptors and immune cells. 25 Under standard conditions, noxious stimuli and painful sensations gradually decrease with the progression of healing.

Freeze-frame: U of A researchers develop microscope that can see electrons in motion

Imagine owning a camera so powerful it can take freeze-frame photographs of a moving electron – an object traveling so fast it could circle the Earth many times in a second. Researchers at the University of Arizona have developed the world’s fastest electron microscope that can do just that.

They believe their work will lead to groundbreaking advancements in physics, chemistry, bioengineering, materials sciences and more.

“When you get the latest version of a smartphone, it comes with a better camera,” said Mohammed Hassan, associate professor of physics and optical sciences. “This transmission electron microscope is like a very powerful camera in the latest version of smartphones; it allows us to take pictures of things we were not able to see before – like electrons. With this microscope, we hope the scientific community can understand the quantum physics behind how an electron behaves and how an electron moves.”

Successful experiment paves the way for discovery of a new element

The search for new elements comes from the dream of finding a variant that is sufficiently stable to be long-lived and not prone to immediate decay. There is a theory in nuclear physics about an island of stability of superheavy elements. This is a potential zone in the upper part of the periodic table of as-yet-undiscovered elements that could remain stable for longer than just a few seconds. The aim is to explore the limits of stability of atomic nuclei.

Lithium Supply Crisis Averted: New Technology Doubles Extraction Efficiency

The demand for lithium, essential for powering sustainable technologies, is rising quickly, yet current methods leave up to 75% of the world’s lithium-rich saltwater sources inaccessible.

With some predicting global lithium supply could fall short of demand as early as 2025, the innovative technology – EDTA-aided loose nanofiltration (EALNF) – sets a new standard in lithium processing. The technology uniquely extracts both lithium and magnesium simultaneously, unlike traditional methods that treat magnesium salts as waste, making it smarter, faster and more sustainable.

The work, co-led by Dr Zhikao Li, from the Monash Suzhou Research Institute and the Department of Chemical and Biological Engineering, and Professor Xiwang Zhang from the University of Queensland, promises to meet the surging demand for lithium and paves the way for more sustainable and efficient extraction practices.

This Radical New Farming Method Would Replace Photosynthesis With Solar Power

The reason? While sunny regions naturally provide enough light to grow crops, areas with colder winters often need grow lights and greenhouses part of the year. This increases energy consumption, logistical headaches, and ultimately, food costs.

In their paper, Jiao and colleagues argue for a new method that could dramatically revamp farming practices to reduce land use and greenhouse gas emissions.

Dubbed “electro-agriculture,” the approach uses solar panels to trigger a chemical reaction that turns ambient CO2 into an energy source called acetate. Certain mushrooms, yeast, and algae already consume acetate as food. With a slight genetic tweak, we could also engineer other common foods such as grains, tomatoes, or lettuce to consume acetate.

Study: Robotic automation, AI will speed up scientific progress in science laboratories

Science laboratories across disciplines—chemistry, biochemistry and materials science—are on the verge of a sweeping transformation as robotic automation and AI lead to faster and more precise experiments that unlock breakthroughs in fields like health, energy and electronics.

This is according to UNC-Chapel Hill researchers in a paper titled “Transforming Science Labs into Automated Factories of Discovery,” published in Science Robotics.

“Today, the development of new molecules, materials and requires intensive human effort,” said Dr. Ron Alterovitz, senior author of the paper and Lawrence Grossberg Distinguished Professor in the Department of Computer Science. “Scientists must design experiments, synthesize materials, analyze results and repeat the process until desired properties are achieved.”

Unlocking the Mysteries of Celestial Flow Features

“Through our simulated impacts, we found that the pure water froze too quickly in a vacuum to effect meaningful change, but salt and water mixtures, or brines, stayed liquid and flowing for a minimum of one hour,” said Dr. Michael J. Poston.

How does extra salty water, also known as briny water, form and evolve on worlds without atmospheres, such as asteroids and moons? This is what a recent study published in The Planetary Science Journal hopes to address as a team of researchers investigated how briny water could still flow for a period of time on the asteroid Vesta after large impacts resulted in the melting of subsurface ice. This study holds the potential to help researchers better understand the geological and chemical processes on planetary bodies without atmospheres and what this could mean for finding life as we know it.

“We wanted to investigate our previously proposed idea that ice underneath the surface of an airless world could be excavated and melted by an impact and then flow along the walls of the impact crater to form distinct surface features,” said Dr. Jennifer Scully, who is a planetary geologist at NASA’s Jet Propulsion Laboratory (JPL) and a co-author on the study.

For the study, the researchers used a JPL test chamber to analyze how liquid samples responded to rapid drops in atmospheric pressure on the asteroid Vesta, thus simulating the conditions of a high-speed impact, which also includes the very brief creation of an atmosphere resulting from that impact. In the end, the researchers made some intriguing findings that could help scientists better understand the geological and chemical processes that occur on planetary bodies without atmospheres.

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