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Archive for the ‘chemistry’ category: Page 101

Jul 26, 2023

Characterizing atomic defects in 2D materials to determine suitability as quantum emitters

Posted by in categories: chemistry, quantum physics

The term molybdenum disulfide may sound familiar to some car drivers and mechanics. No wonder: the substance, discovered by U.S. chemist Alfred Sonntag in the 1940s, is still used today as a high-performance lubricant in engines and turbines, but also for bolts and screws.

This is due to the special chemical structure of this solid, whose individual material layers are easily displaceable relative to one another. However, molybdenum disulfide (chemically MoS2) not only lubricates well, but it is also possible to exfoliate a single atomic layer of this material or to grow it synthetically on a wafer scale.

The controlled isolation of a MoS2 monolayer was achieved only a few years ago, but is already considered a materials science breakthrough with enormous technological potential. The Empa team now wants to work with precisely this class of materials.

Jul 26, 2023

Machine learning enables discovery of DNA-stabilized silver nanoclusters

Posted by in categories: biotech/medical, chemistry, genetics, robotics/AI

DNA can do more than pass genetic code from one generation to the next. For nearly 20 years, scientists have known of the molecule’s ability to stabilize nanometer-sized clusters of silver atoms. Some of these structures glow visibly in red and green, making them useful in a variety of chemical and biosensing applications.

Stacy Copp, UCI assistant professor of materials science and engineering, wanted to see if the capabilities of these tiny fluorescent markers could be stretched even further—into the near-infrared range of the electromagnetic spectrum—to give bioscience researchers the power to see through living cells and even centimeters of biological tissue, opening doors to enhanced methods of disease detection and treatment.

“There is untapped potential to extend fluorescence by DNA-stabilized silver nanoclusters into the near-infrared region,” she says. “The reason that’s so interesting is because our biological tissues and fluids are much more transparent to near-infrared light than to visible light.”

Jul 25, 2023

AI Unlocks Olive Oil’s Potential in Alzheimer’s Battle

Posted by in categories: biotech/medical, chemistry, robotics/AI

This is a good use of AI. Definitely regular it but I can see it’s contributing to medical research.


Summary: Researchers have utilized artificial intelligence to uncover the promising potential of extra virgin olive oil (EVOO) in combating Alzheimer’s disease (AD).

By integrating AI, chemistry, and omics research, the study identified specific bioactive compounds in EVOO that could contribute to the treatment and prevention of AD. Ten phytochemicals within EVOO, such as quercetin, genistein, luteolin, and kaempferol, were found to exhibit potential impacts on AD protein networks.

Continue reading “AI Unlocks Olive Oil’s Potential in Alzheimer’s Battle” »

Jul 25, 2023

Underground Cells Make ‘Dark Oxygen’ Without Light

Posted by in category: chemistry

In some deep subterranean aquifers, cells have a chemical trick for making oxygen that could sustain whole underground ecosystems.

Jul 25, 2023

Artificial intelligence and molecule machine join forces to generalize automated chemistry

Posted by in categories: chemistry, robotics/AI

Year 2022 😗😁


Better chemistry through computing: #ILLINOIS researchers led an international team that combined powerful AI and a molecule-making machine to automate complex chemistry.

Jul 25, 2023

Potent anti-cancer therapy created using ‘click chemistry’

Posted by in categories: biotech/medical, chemistry

A potent anti-cancer therapy has been created using Nobel prize-winning “click chemistry,” where molecules click together like LEGO bricks, in a new study by UCL and Stanford University researchers.

The study, published in Nature Chemistry, opens up new possibilities for how cutting-edge cancer immunotherapies might be built in future.

The research team created an anti-cancer therapy with three components: one targeting the cancer cell, another recruiting a white blood cell called a T cell to attack the cancer cell, and a third knocking out part of the cancer cell’s defenses.

Jul 25, 2023

Researchers describe ‘nanoclays,’ an innovative addition to tools for chemists

Posted by in categories: biotech/medical, chemistry, engineering

Microscopic materials made of clay, designed by researchers at the University of Missouri, could be key to the future of synthetic materials chemistry. By enabling scientists to produce chemical layers tailor-made to deliver specific tasks based on the goals of the individual researcher, these materials, called nanoclays, can be used in a wide variety of applications, including the medical field or environmental science.

A paper describing this research is published in the journal ACS Applied Engineering Materials.

A fundamental part of the material is its electrically charged surface, said Gary Baker, co-principal investigator on the project and an associate professor in the Department of Chemistry.

Jul 24, 2023

Distinguished Lecture Series | Why life began with RNA | Trivedi School of Biosciences

Posted by in categories: biotech/medical, chemistry

This video, which is a part of the Distinguished Lecture Series by Trivedi School of Biosciences, Ashoka University, Prof. Jack W. Szostak discusses why life began with RNA. Why was Ribose sugar chosen in the primordial soup, and not several other alternative sugars that may have been available? He shows this using elegant experiments that include chemistry and structural biology.

Distinguished Speaker: Prof. Jack W. Szostak.
2009 Nobel Laureate in Physiology or Medicine.

Continue reading “Distinguished Lecture Series | Why life began with RNA | Trivedi School of Biosciences” »

Jul 24, 2023

The Origin of Life: Not as Hard as it Looks? Jack Szosta, Spring 2023 Eyring Lecturer

Posted by in category: chemistry

Nobel laureate Jack Szostak from University of Chicago delivered the Eyring General Lecture on March 17, 2023 at Arizona State University. Please click here to learn more about Dr. Szosta and the distinguished Eyring Lecture Series at ASU. https://news.asu.edu/20230309-nobel-laureate-jack-szostak-de…series-asu.

#chemistry #research @arizonastateuniversity @ASUNews

Jul 24, 2023

Natural Compounds That Target DNA Repair Pathways and Their Therapeutic Potential to Counteract Cancer Cells

Posted by in categories: biotech/medical, chemistry

Resistance to current cancer treatments is an important problem that arises through various mechanisms, but one that stands out involves an overexpression of several factors associated with DNA repair. To counteract this type of resistance, different drugs have been developed to affect one or more DNA repair pathways, therefore, to test different compounds of natural origin that have been shown to induce cell death in cancer cells is paramount. Since natural compounds target components of the DNA repair pathways, they have been shown to promote cancer cells to be resensitized to current treatments. For this and other reasons, natural compounds have aroused great curiosity and several research projects are being developed around the world to establish combined treatments between them and radio or chemotherapy. In this work, we summarize the effects of different natural compounds on the DNA repair mechanisms of cancer cells and emphasize their possible application to re-sensitize these cells.

Day by day we are exposed to chemical carcinogens in the environment, ultraviolet (UV) radiation, ionizing radiation, and also those substances produced in our body during cellular metabolism that attack and produce a variety of DNA injuries. Each lesion favors the development of alterations in DNA and chromosomes, which favors oncogenic transformation and tumor progression. In order to reduce the number of changes in the genome and its instability, cells have several pathways of response to damage and DNA repair proteins that eliminate these lesions. DNA adducts, such as those created by alkylating agents, can be cleaved and repaired by base excision repair (BER) or by nucleotide excision repair (NER), depending on whether it is necessary to remove only a nitrogenous base or a nucleotide. Also, O-6-methylguanine-DNA methyltransferase (MGMT), an alkyltransferase, eliminates alkylations.

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