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Genflow has announced that its adeno-associated virus (AAV) research and development programme in Estonia has received a non-dilutive grant award of €250,000 from the Applied Research Programme of Enterprise Estonia, an Estonian governmental institution designed to stimulate business growth in the country.

Longevity. Technology: Genflow’s research programme is focused on the development of an antiaging gene therapy platform designed to target nearly 100 million patients worldwide who suffer from Werner’s syndrome, non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis, an advanced form of NAFLD, as well as other major clinical disorders.

This R&D is a collaborative project between Genflow and IVEX lab OÜ, an Estonian company specialising in the research and development of biotech therapeutics.

Scientists have transplanted human brain cells into the brains of baby rats, where the cells grew and formed connections.

It’s part of an effort to better study human brain development and diseases affecting this most complex of organs, which makes us who we are but has long been shrouded in mystery.

“Many disorders such as autism and schizophrenia are likely uniquely human” but “the human brain certainly has not been very accessible,” said said Dr. Sergiu Pasca, senior author of a study describing the work, published Wednesday in the journal Nature.

Prior to this, it was assumed that egg cells (oocytes) would contain a complex array of factors needed to reprogram a somatic cell into becoming an embryonic cell. After all, the feat of transforming an aged egg cell and reprogramming it to make a new animal must be controlled by many factors present in the egg cell, or so they thought. Takahashi and Yamanaka turned this idea upside down when they showed that just four of the Yamanaka factors were needed to achieve this transformation.

They used the Yamanaka factors to reprogram adult mouse fibroblasts (connective tissue cells) back to an embryonic state called pluripotency, a state where the cell behaves like an embryonic stem cell and can become any other cell type in the body.

This discovery paved the way for research into how these Yamanaka factors might be used for cellular rejuvenation and a potential way to combat age-related diseases.

From superfast magnetic levitation trains and computer chips to magnetic resonance imaging (MRI) machines and particle accelerators, superconductors are electrifying various aspects of our life. Superconductivity is an interesting property that allows materials to transfer moving charges without any resistance, below a certain critical point. This implies that superconducting materials can transfer electrical energy in a highly efficient manner without loss in the form of heat, unlike many conventional conductors.

Almost two decades ago scientists discovered superconductivity in a —magnesium diboride, or MgB2. There has been a resurgence in the of popularity MgB2 due to its low cost, superior superconducting abilities, high critical current density (which means that compared to other materials, MgB2 remains a semiconductor even when larger amounts of electric current is passed through it), and trapped magnetic fields arising from strong pinning of the vortices—which are cylindrical current loops or tubes of magnetic flux that penetrate a superconductor.

The intermetallic MgB2 also allows adjustability of its properties. For instance, the critical current density values (Jc) of MgB2 can be improved by decreasing the grain size and increasing the number of grain boundaries. Such adjustability is not observed in conventional layered superconductors.

Live biological neurons show more about how a brain works than AI ever will.

Scientists have shown for the first time that 800,000 brain cells living in a dish can perform goal-directed tasks. In this case, they played the simple tennis-like computer game, Pong. The results of the Melbourne-led study are published today (October 12) in the journal Neuron.

Now the researchers are going to investigate what happens when their DishBrain is affected by medicines and alcohol.

https://youtube.com/watch?v=Pr5aRhEIE9A&feature=share

‎Researchers from the Chinese Communist Party (CCP) claimed in a recently published study to have developed a gene editing method that is supposed to be “more efficient and safer” than the technique used so far.

But there is a lot behind gene editing, so let’s look at what it is all about and its risks and applications.
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#ChinaRevealed #ChinaNews

UW Medicine researchers have found that algorithms are as good as trained human evaluators at identifying red-flag language in text messages from people with serious mental illness. This opens a promising area of study that could help with psychiatry training and scarcity of care.

The findings were published in late September in the journal Psychiatric Services.

Text messages are increasingly part of mental health care and evaluation, but these remote psychiatric interventions can lack the emotional reference points that therapists use to navigate in-person conversations with patients.