Lifeboat Foundation

DeepMind and EMBL release the most complete database of predicted 3D structures of human proteins.

Partners use AlphaFold, the AI system recognized last year as a solution to the protein structure prediction problem, to release more than 350000 protein structure predictions including the entire human proteome to the scientific community.

DeepMind today announced its partnership with the European Molecular Biology Laboratory (EMBL), Europe’s flagship laboratory for the life sciences, to make the most complete and accurate database yet of predicted protein structure models for the human proteome. This will cover all ~20000 proteins expressed by the human genome, and the data will be freely and openly available to the scientific community. The database and artificial intelligence system provide structural biologists with powerful new tools for examining a protein’s three-dimensional structure, and offer a treasure trove of data that could unlock future advances and herald a new era for AI-enabled biology.

Brain–computer interfaces (BCIs) provide bidirectional communication between the brain and output devices that translate user intent into function. Among the different brain imaging techniques used to operate BCIs, electroencephalography (EEG) constitutes the preferred method of choice, owing to its relative low cost, ease of use, high temporal resolution, and noninvasiveness. In recent years, significant progress in wearable technologies and computational intelligence has greatly enhanced the performance and capabilities of EEG-based BCIs (eBCIs) and propelled their migration out of the laboratory and into real-world environments. This rapid translation constitutes a paradigm shift in human–machine interaction that will deeply transform different industries in the near future, including healthcare and wellbeing, entertainment, security, education, and marketing. In this contribution, the state-of-the-art in wearable biosensing is reviewed, focusing on the development of novel electrode interfaces for long term and noninvasive EEG monitoring. Commercially available EEG platforms are surveyed, and a comparative analysis is presented based on the benefits and limitations they provide for eBCI development. Emerging applications in neuroscientific research and future trends related to the widespread implementation of eBCIs for medical and nonmedical uses are discussed. Finally, a commentary on the ethical, social, and legal concerns associated with this increasingly ubiquitous technology is provided, as well as general recommendations to address key issues related to mainstream consumer adoption.

When will Neuralink be available to healthy individuals? It’s difficult to find a coherent train of thought pertaining to this question specifically.

Recently, I’ve started thinking more in terms of regulatory approval rather than rough timeline estimates. This sent me down a fascinating path learning more about how medical devices in general make it through “the system.”

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RT Documentary’s new film Russia’s NICA: Big Bang questions takes you to the Russian nuclear facility in Dubna where a collider is being built as part of the NICA mega-science project. It can recreate the beginning of the world 14 billion years ago.

This research can be used to learn how the universe was formed, according to the Big Bang theory, and the data obtained in the process will be essential to many other areas of science.
The Joint Institute for Nuclear Research in Dubna has been operating since Soviet times, and this is where the Synchrophasotron elementary particle accelerator was built in the 1960s. It is still functional and can be used, but it takes an excessive amount of energy. Nevertheless, it remains a monument to Soviet science and the attempts to learn about the universe.

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To quickly express learning and memory genes, brain cells snap both strands of DNA in many more places and cell types than previously realized, a new study shows.

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations — more than previously realized, according to a new study — to provide quick access to genetic instructions for the mechanisms of memory storage.

The extent of these DNA double-strand breaks (DSBs) in multiple key brain regions is surprising and concerning, says study senior author Li-Huei Tsai, Picower Professor of Neuroscience at MIT and director of The Picower Institute for Learning and Memory, because while the breaks are routinely repaired, that process may become more flawed and fragile with age. Tsai’s lab has shown that lingering DSBs are associated with neurodegeneration and cognitive decline and that repair mechanisms can falter.

A program has been used to predict the structures of nearly every protein in the human body.

A study looks at an ancestral recombination graph of the genomes of modern humans, Neanderthals, and Denisovans to map how much of our genome is shared.

Check out our new promo for #transvision #future Summit 2021! Get your tickets! -> www.TransVisionMadrid.com There will be talks about #longevity #artificialintelligence #cryonics and much much more. You will also be able to network with speakers and attendees during 5 optional dinner/cocktails, and 2 tours of several UNESCO heritage sites and historical places: Ávila, Segovia, Monsaterio de El Escorial, Valle de los Caídos (Valley of the Fallen), Aranjuez & Toledo.

Humanity Plus Humanity Plus Humanity Plus Magazine MUTISHAN Interactive Vivian Francos #SEOHashtag Alcor Life Extension Foundation Cryonics Institute Cryonics Institute SENS Research Foundation SENS Research Foundation Posthuman Network Posthuman Network Cryonics4U Longevity Conferences Longevity for All U.S. Transhumanist Party Transhumanist Party Australia Transhumanist Party Virtual Rational Transhumanism Singularity University Ray Kurzweil Singularity Singularity Hub Ray Kurzweil’s Singularity Singularity Network Transhumanismo Brasil Transhumanismo Brasil TRANSHUMANISMO Christian Transhumanist Association Mormon Transhumanist Association SingularityNET Singularitarianism Foresight Institute Lifeboat Foundation Lifeboat Foundation Machine Intelligence Research Institute KrioRus The Hedonistic Imperative — Paradise Engineering.

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Paper referenced in the video:

Potential reversal of epigenetic age using a diet and lifestyle.
intervention: a pilot randomized clinical trial.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8064200/

Continue reading “Epigenetic Age Reduction Within 8 Weeks: Real Effect Or Statistical Noise?” »