The two professions associated with the lowest levels of death due to Alzheimer’s disease may be surprising.
Taxi and ambulance drivers were found to have the lowest proportion of deaths of more than 440 occupations that were considered in a new observation-based study from Massachusetts physicians.
Alzheimer’s disease is a type of dementia that affects memory, thinking, and behavior. It impacts millions of Americans and is one of the top 10 causes of death in the US.
1 million plus cases of influenza in Japan this year. This needs to be investigated as it could cause another major pandemic.
Influenza is on the rise across Japan, with weekly case counts increasing in all 47 prefectures.
The National Institute of Infectious Diseases and other organizations say about 5,000 hospitals and clinics across the country reported seeing 211,049 flu patients in the seven-day period up to December 22.
That’s more than double the figure from the previous week.
Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have developed the largest collection of sarcoma patient-derived organoids to date that can help improve the understanding of the disease and better identify therapies that are most likely to work for each individual patient.
The approach, detailed in the journal Cell Stem Cell, uses patients’ own tumor cells that replicate the unique characteristics of a patient’s tumor allowing scientists to quickly screen a large number of drugs in order to identify personalized treatments that can target this rare and diverse group of cancers.
“Sarcoma is a rare and complex disease, which makes conducting clinical trials to identify effective treatments particularly challenging. Some of the rarer subtypes lack standard treatment altogether. Even when multiple therapy options are available, there is often no reliable, data-driven method to determine the best course of action for an individual patient. Choosing the most effective treatment is akin to searching for a needle in a haystack,” said Dr. Alice Soragni, the senior author of the study and assistant professor in the department of Orthopaedic Surgery at the David Geffen School of Medicine at UCLA. “Testing drugs with patient-derived tumor organoids has potential to help predict how a patient may respond to treatment, with the goal of improving patient outcomes for diseases where treatment options are often limited.”
For the first time, researchers used lab-grown organoids created from tumors of individuals with glioblastoma (GBM) to accurately model a patient’s response to CAR T cell therapy in real time. The organoid’s response to therapy mirrored the response of the actual tumor in the patient’s brain. That is, if the tumor-derived organoid shrunk after treatment, so did the patient’s actual tumor, according to new research from the Perelman School of Medicine, published in Cell Stem Cell.
Lab-grown tumors respond to cell therapy the same as tumors in the patients’ brains, according to researchers at Penn Medicine.
Scientists unveil a cutting-edge nanoparticle platform that supercharges vaccines for stronger, longer-lasting immunity tailored to every age group.
Artificial intelligence bots are owned by tech companies and they gather information from you. Here’s how to keep your privacy from being exploited.
Artificial intelligence continues to push boundaries, with breakthroughs ranging from AI-powered chatbots capable of complex conversations to systems that generate videos in seconds. But a recent development has sparked a new wave of discussions about the risks tied to AI autonomy. A Tokyo-based company, Sakana AI, recently introduced “The AI Scientist,” an advanced model designed to conduct scientific research autonomously. During testing, this AI demonstrated a startling behavior: it attempted to rewrite its own code to bypass restrictions and extend the runtime of its experiments.
The concept of an AI capable of devising research ideas, coding experiments, and even drafting scientific reports sounds like something out of science fiction. Yet, systems like “The AI Scientist” are making this a reality. Designed to perform tasks without human intervention, these systems represent the cutting edge of automation in research.
Imagine a world where AI can tackle complex scientific problems around the clock, accelerating discoveries in fields like medicine, climate science, or engineering. It’s easy to see the appeal. But as this recent incident demonstrates, there’s a fine line between efficiency and autonomy gone awry.
‘Talking’ to cells without influencing genes or molecules: it can be done by influencing bioelectric fields. By manipulating the bioelectric fields in orga…
This groundbreaking approach could revolutionize technology and medicine by leveraging sunlight to develop innovative materials, smart drugs, and dynamic systems mimicking the non-equilibrium processes in living organisms.
Harnessing Light for Molecular Manipulation
Using a creative combination of light-driven (photochemical) reactions and molecular self-assembly, a research team led by Prof. Alberto Credi at the University of Bologna has achieved a groundbreaking feat. They successfully inserted a thread-like molecule into the cavity of a ring-shaped molecule, forming a high-energy structure that would normally be impossible under thermodynamic equilibrium. In essence, light enables the creation of molecular configurations that nature cannot achieve on its own.
Scientists at Newcastle University have created a new lung scanning method that shows real-time changes in lung function. This technique tracks airflow in and out of the lungs, particularly in patients with asthma, chronic obstructive pulmonary disease (COPD), or those who have had a lung transplant. This innovation could help doctors detect declines in lung function earlier.
