The FDA on Friday approved Regeneron Pharmaceuticals’ Veopoz (pozelimab-bbfg), the first and only treatment indicated specifically for CHAPLE disease, also known as CD55-deficient protein-losing enteropathy, according to the company.

A fully human monoclonal antibody, Veopoz is approved for the treatment of adult and pediatric patients 1 year of age and older with CHAPLE, an ultra-rare hereditary disease that can cause potentially life-threatening gastrointestinal and cardiovascular symptoms.

- CHAPLE—which stands for complement hyperactivation, angiopathic thrombosis, and protein-losing enteropathy—is an inherited immune disease that causes the complement system (the part of your immune system that defends the body against injury and foreign invaders like bacteria and viruses) to become overactive.-FDA.

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The regulator’s greenlight on Friday for Regeneron Pharmaceuticals’ monoclonal antibody Veopoz (pozelimab-bbfg) makes it the first and only treatment indicated for children and adults with CHAPLE disease.

Chiral molecules are those that have two versions that are mirror images, like our right and left hands. These molecules have the same structure but different properties when they interact with other molecules, including those inside our bodies. This is important for example in drug molecules, where only the right-or left-handed version may have the desired effect.

Detecting and quantifying the chirality of matter however has been difficult. Current methods using a form of light that produces a (right-or left-twisting) helix have the problem that each turn of the helix is much larger than the molecules. This creates important challenges for detecting molecular chirality.

Now, researchers at Imperial College London, with collaborators in Germany and Spain, have come up with a new way to use light to detect chirality. Instead of making light helix in space, they have devised a way to make it helix in time using lasers with moderate intensities.

Australian researchers have developed a new method to reprogram human cells to better mimic embryonic stem cells called transient-naive-treatment (TNT).

Stem cells, serving as a repair system for our body, generate all other cells with specialized functions. There are two main types of stem cells: embryonic stem cells and adult stem cells.

In a scientific advancement in the 2000s, it was discovered that somatic cells, which are responsible for the growth and development of an organism, could be artificially reprogrammed into a state that resembles embryonic stem (ES) cells, also known as induced pluripotent stem (iPS) cells. These cells can then generate any cell in the body.