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Category: biotech/medical – Page 638

This is good news! The article says this could lead to treatment of other cancers.

A particularly aggressive form of childhood cancer that forms in muscle tissue might have a new treatment option on the horizon.

Scientists have successfully induced rhabdomyosarcoma cells to transform into normal, healthy muscle cells. It’s a breakthrough that could see the development of new therapies for the cruel disease, and it could lead to similar breakthroughs for other types of human cancers.

“The cells literally turn into muscle,” says molecular biologist Christopher Vakoc of Cold Spring Harbor Laboratory.

Continue reading “Aggressive Cancer Cells Transformed Into Healthy Cells in Breakthrough” | >

#ted.
#wifi.
#internet.

What about 102,400 MBPS or 100GBPS. This is the speed of data transfer that you can achieve with LiFi Technology. With LiFi you can download 100 movies in just one second.
How’s this incredible internet speed possible?
It is possible with LED lights.
Watch this video till the end for a detailed introduction and truths of LiFi technology.

NEW HERE! TRY THIS STUFF

Continue reading “LiFi — This is the Fastest Internet in the World (224GBPS) — Easiest Explanation Ever!” | >

Rohit Chikkaraddy/ University of Birmingham.

Mid-infrared, as the name suggests, lies between the infrared spectrum’s near and far wavelengths, just outside those of visible light. The mid-infrared spectrum has gained particular importance as it has been useful for multiple applications ranging from military to environmental and medical treatments and studying celestial objects.

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1 Department of Biotechnology, School of Science, GITAM (Deemed to be University), Visakhapatnam, Andhra Pradesh, 530,045, India; 2 Department of Cell and Developmental Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61,801, USA

Correspondence: Sireesha V Garimella; Pankaj Chaturvedi, Email [email protected]; [email protected]

Abstract: Cancer continues to rank among the world’s leading causes of mortality despite advancements in treatment. Cancer stem cells, which can self-renew, are present in low abundance and contribute significantly to tumor recurrence, tumorigenicity, and drug resistance to various therapies. The drug resistance observed in cancer stem cells is attributed to several factors, such as cellular quiescence, dormancy, elevated aldehyde dehydrogenase activity, apoptosis evasion mechanisms, high expression of drug efflux pumps, protective vascular niche, enhanced DNA damage response, scavenging of reactive oxygen species, hypoxic stability, and stemness-related signaling pathways. Multiple studies have shown that mitochondria play a pivotal role in conferring drug resistance to cancer stem cells, through mitochondrial biogenesis, metabolism, and dynamics. A better understanding of how mitochondria contribute to tumorigenesis, heterogeneity, and drug resistance could lead to the development of innovative cancer treatments.

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If your mother says she loves you: check it.

A couple weeks ago, I asked Vergecast.

What I was not expecting was for so many people to send me versions of a video that shows a banana getting stitches in a robotic surgery device, with the captions claiming that the surgery is being done remotely over 5G. This video has had an … More.

Meet Dr. Kais Rona, who is as befuddled by the lie appended to his video as anyone else.

Continue reading “No, they did not do surgery on a banana over 5G” | >

The article titled “Evaluation of OVX836: A Promising Universal Influenza Vaccine Candidate” published in The Lancet presents a comprehensive assessment of OVX836, a novel influenza vaccine candidate targeting the nucleoprotein of influenza A virus. Authored by a team of researchers led by IL-R at CEVAC Clinical Unit and Laboratory, the study aims to investigate the safety, immunogenicity, and potential efficacy of OVX836 at different doses, shedding light on its potential as a universal influenza vaccine.

Influenza remains a significant global health concern, with seasonal epidemics and occasional pandemics causing substantial morbidity and mortality. Current influenza vaccines primarily focus on the viral surface protein hemagglutinin, but their efficacy is limited by antigenic variation and the emergence of new strains. Current vaccines are developed for the season based on what strains were prominent in the last season. Additionally, vaccine efficacies can vary from season to season. OVX836 takes a different approach by targeting the highly conserved nucleoprotein, which plays a crucial role in the influenza virus life cycle.

OVX836 elicited a robust immune response, characterized by significant increases in nucleoprotein-specific CD4 and CD8 T-cell responses, as well as the production of anti-nucleoprotein IgG antibodies. The magnitude of these immune responses displayed a dose-dependent relationship, with higher doses of OVX836 leading to stronger immune reactions. Of particular interest was the induction of a CD8 T-cell response, a rare achievement for influenza vaccines and a crucial component of comprehensive immune protection.

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“A major highlight of the work is our approach to achieve longevity: using computers to simulate the natural aging system and guide the design and rational engineering of the system to extend lifespan,” Hao told Motherboard. “This is the first time this computationally-guided engineering-based approach has been used in aging research. Our model simulations actually predicted that an oscillator can double the lifespan of the cell, but we were happily surprised that it actually did in experiments.”

The study is part of a growing corpus of mind-boggling research that may ultimately stave off some of the unpleasant byproducts of aging until later in life, while boosting life expectancy in humans overall. Though countless hurdles have to be cleared before these treatments become a reality, Hao thinks his team’s approach could eventually be applied to humans.

“I don’t see why it cannot be applied to more complex organisms,” Hao said. “If it is to be introduced to humans, then it will be a certain form of gene therapy. Of course it is still a long way ahead and the major concerns are on ethics and safety.”

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