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Scientists at a university in the UK are in the midst of creating a breakthrough vaccine that could stop cancer in its tracks.
Category: biotech/medical – Page 581
Multifaceted Effects of Kinase Inhibitors on Pancreatic Cancer Cells Reveals Pivotal Entities with Therapeutic Implications
📝 — Kim, et al.
The goal of the present study was to identify potential pivotal molecules with implications for novel and efficacious treatment options for pancreatic cancer, a disease with limited treatments available and notorious for its aggressive nature.
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Pancreatic cancer is one of the most aggressive forms of cancer and is the seventh leading cause of cancer deaths worldwide. Pancreatic ductal adenocarcinoma (PDAC) accounts for over 90% of pancreatic cancers. Most pancreatic cancers are recalcitrant to radiation, chemotherapy, and immunotherapy, highlighting the urgent need for novel treatment options for this deadly disease. To this end, we screened a library of kinase inhibitors in the PDAC cell lines PANC-1 and BxPC-3 and identified two highly potent molecules: Aurora kinase inhibitor AT 9,283 (AT) and EGFR kinase inhibitor WZ 3,146 (WZ). Both AT and WZ exhibited a dose-dependent inhibition of viability in both cell lines.
Hear ye! Hear ye! Previously unknown set of cochlear hearing modes supports complexities in human hearing
Yale physicists have discovered a sophisticated, previously unknown set of “modes” within the human ear that put important constraints on how the ear amplifies faint sounds, tolerates noisy blasts, and discerns a stunning range of sound frequencies in between.
By applying existing mathematical models to a generic mock-up of a cochlea—a spiral-shaped organ in the inner ear—the researchers have revealed a new layer of cochlear complexity. The findings, which appear in PRX Life, offer fresh insight into the remarkable capacity and accuracy of human hearing.
“We set out to understand how the ear can tune itself to detect faint sounds without becoming unstable and responding even in the absence of external sounds,” said Benjamin Machta, an assistant professor of physics in Yale’s Faculty of Arts and Science and co-senior author of the new study. “But in getting to the bottom of this we stumbled onto a new set of low frequency mechanical modes that the cochlea likely supports.”
Nonlinear optical crystal for ultraviolet lasers remains remarkably stable under extreme pressure
Researchers from Oakland University have made a significant breakthrough in the field of optical materials, unveiling the exceptional capabilities of Ba₃(ZnB₅O₁₀)PO₄ (BZBP). Although this transparent crystal closely resembles ordinary window glass, it exhibits extraordinary properties that set it apart from others.
Already renowned for its exceptional qualities, such as excellent heat dissipation, minimal uneven expansion when exposed to temperature changes, and the ability to transmit ultraviolet light (a type of light that comes from the sun and other sources like special lamps, but it’s invisible to the human eye), BZBP has emerged as an ideal choice for laser systems operating in deep ultraviolet ranges. These systems are crucial in fields such as medical diagnostics, semiconductor production, and cutting-edge scientific research.
In a study recently published in Advanced Functional Materials, researchers explored how BZBP performs under extreme pressure.
Butterfly-inspired robot wings can work without batteries, motors
Inspired by butterfly wings, a team of German researchers have developed a new kind of robotic wings that can work using only magnetic fields. The new wings created by the Technical University of Darmstadt and the Helmholtz Center Dresden-Rossendorf researchers need no batteries or electronics.
They could have interesting applications from search and rescue to medical sciences. The researchers drew inspiration from the remarkable efficiency and endurance of monarch butterflies, known to have incredibly long migrations between Canada and Mexico.
A new experimental system to bring quantum technologies closer to students
The world of quantum physics is experiencing a second revolution, which will drive an exponential leap in the progress of computing, the internet, telecommunications, cybersecurity and biomedicine.
Quantum technologies are attracting more and more students who want to learn about concepts from the subatomic world—such as quantum entanglement or quantum superposition —to explore the innovative potential of quantum science.
In fact, understanding the non-intuitive nature of quantum technology concepts and recognizing their relevance to technological progress is one of the challenges of 2025, declared the International Year of Quantum Science and Technology by UNESCO.
A Paralyzed Man Just Piloted a Virtual Drone With His Mind Alone
Now, thanks to a brain implant, he’s experienced the thrill in a simulation. By picturing finger movements in his mind, the 69-year-old flew a virtual drone in a video game, with the quadcopter dodging obstacles and whizzing through randomly appearing rings in real time.
T5 is part of the BrainGate2 Neural Interface System clinical trial, which launched in 2009 to help paralyzed people control computer cursors, robotic arms, and other devices by decoding electrical activity in their brains. It’s not just for gaming. Having the ability to move and click a cursor gets them back online. Googling, emailing, streaming shows, scrolling though social media posts—what able-bodied people spend hours on every day—are now again part of their lives.
But cursors can only do so much. Popular gaming consoles—PlayStation, Xbox, Nintendo Switch—require you to precisely move your fingers, especially thumbs, fast and in multiple directions.
REM Sleep Delays May Indicate Early Alzheimer’s
Summary: Delayed rapid eye movement (REM) sleep may be an early indicator of Alzheimer’s disease. Researchers found that participants with delayed REM sleep had higher levels of toxic proteins associated with Alzheimer’s and reduced levels of brain-derived neurotrophic factor (BDNF), which supports memory.
Delayed REM sleep disrupts memory consolidation and increases stress hormone levels, which can impair the hippocampus, a critical brain region for learning and memory. The findings emphasize the importance of healthy sleep habits and suggest that treatments targeting sleep patterns may influence Alzheimer’s progression.
DNA Digital Data Storage (a NEW Era of Technology)
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Welcome to an enlightening exploration of DNA Digital Data Storage — a groundbreaking advancement signaling a new era of technology. As we stand on the cusp of unprecedented tech evolution, DNA storage emerges as a game-changing alternative to traditional storage methods.
Understanding DNA Digital Data Storage is vital for anyone keen to dive deep into the future of data solutions. This video demystifies the intricacies behind this pioneering concept, shedding light on its potential to revolutionize how we perceive data storage and retrieval. With today’s rapid generation of digital data, our existing solutions are often overwhelmed. Enter DNA storage, which offers immense capacities, extending into petabytes and exabytes, all while consuming minimal physical space.
As technology enthusiasts, researchers, and innovators look for sustainable, long-term storage options, DNA-based storage presents a fascinating convergence of biology and digital tech. The microscopic strands of DNA possess the potential to store vast volumes of information, and this video unpacks the science behind this, making it comprehensible for everyone.
Whether you’re a tech enthusiast, an IT professional, or just curious about the advances in the digital realm, this video is tailored to satiate your curiosity. Join us in navigating the transformative world of DNA Digital Data Storage and understanding its pivotal role in ushering us into a new technology era.
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Nano Robots Explained
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Welcome to our comprehensive guide on “Nano Robots.” In this enlightening video, we will take a look at what nano robots are, how they work, and the ways in which they are being used today. We will examine the potential of nano robots and how they could be used in the future. We will also discuss the advantages and disadvantages of using nano robots.
Nano robots are made up of very small robots that are only a few nanometers across and are powered by electricity, magnets, or light. These robots can be used for many different things, like fixing damaged cells, keeping an eye on and controlling the environment, and fighting off diseases and infections. Nano robots can also be used to do hard jobs like surgery, making things, and even going to space.
These robots are very accurate and good at what they do, which makes them perfect for use in medicine and industry. Nano robots can be programmed to do many different things, like keep an eye on and control the environment, find and fix damage, and even fight off diseases and infections. They can also be used for more complicated jobs, like surgery, making things, and going to space.
Nano robots have a lot of benefits, such as being small, accurate, and fast. They are also very flexible because they can be programmed to do many different things and used in many different ways. But there are some problems with using nano robots, such as the cost of making them and the chance that they will break down.
In the end, nano robots are an important part of the future of technology and robotics. They are very small and accurate, and they can be used for many different things. They have many pros and cons, but with the right programming and use, they can change the way people interact with the world around them.
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