Researchers identified a tumor protein signature that predicts chemotherapy sensitivity and favorable clinical outcomes.
Every person starts as just one fertilized egg. By adulthood, that single cell has turned into roughly 37 trillion cells, many of which keep dividing to create the same amount of fresh human cells every few months.
But those cells have a formidable challenge. The average dividing cell must copy — perfectly — 3.2 billion base pairs of DNA, about once every 24 hours. The cell’s replication machinery does an amazing job of this, copying genetic material at a lickety-split pace of some 50 base pairs per second.
A Long Island man who was paralyzed in a diving accident has regained motion and feeling in his body after a breakthrough, machine learning-based surgery that successfully “connected a computer to his brain” through microelectrode implants.
Now, the successful case of Massapequa’s Keith Thomas, 45, is being heralded throughout the medical world as a “pioneer” case for AI-infused surgeries to treat or cure impassible illnesses like blindness, deafness, ALS, seizures, cerebral palsy and Parkinson’s, experts at Manhasset’s Feinstein Institutes for Medical Research boast.
“This is the first time a paralyzed person is regaining movement and sensation by having their brain, body and spinal cord electronically linked together,” Chad Bouton, a professor at Feinstein’s Institute of Bioelectronic Medicine, told The Post.
Materials possessing both strength and lightness have the potential to enhance everything from automobiles to body armor. But usually, the two qualities are mutually exclusive. However, researchers at the University of Connecticut, along with their collaborators, have now crafted an incredibly strong yet lightweight material. Surprisingly, they achieved this using two unexpected building blocks: DNA
DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).
Cancer can cause different, such as abnormal bumps, night sweats, or unexplained weight gain or loss. Only a doctor can tell if are caused by cancer or some other problem.
The STAR party’s vision for Canada includes the research and development of self sustainable Mobile Airborne Cities; or Airborne Arcologies. Being an obviously semi-long term goal, the objective would be to at first, allocate budgeting towards research and development of components to build this project in a phased manner… and the scaling of the project as technology allows for it.
Phase I: research and development of scalable micro-prototypes.
Phase II: multiple prototype development / testing stages.
Continue reading “Stanford Medicine researchers map morphing placenta” »
There’s a lot of talk about the potential for artificial intelligence in medicine, but few researchers have shown through well-designed clinical trials that it could be a boon for doctors, health care providers and patients.
Now, researchers at Stanford Medicine have conducted one such trial; they tested an artificial intelligence algorithm used to evaluate heart function. The algorithm, they found, improves evaluations of heart function from echocardiograms — movies of the beating heart, filmed with ultrasound waves, that show how efficiently it pumps blood.
“This blinded, randomized clinical trial is, to our knowledge, one of the first to evaluate the performance of an artificial intelligence algorithm in medicine. We showed that AI can help improve accuracy and speed of echocardiogram readings,” said James Zou, PhD, assistant professor of biomedical data science and co-senior author on the study. “This is important because heart disease is the leading cause of death in the world. There are over 10 million echocardiograms done each year in the U.S., and AI has the potential to add precision to how they are interpreted.”
NIH-funded study supports new role for nutrient found in fish, dietary supplements.
Omega-3 fatty acids, which are abundant in fish and fish oil supplements, appear promising for maintaining lung health, according to new evidence from a large, multi-faceted study in healthy adults supported by the National Institutes of Health. The study provides the strongest evidence to date of this association and underscores the importance of including omega-3 fatty acids in the diet, especially given that many Americans do not meet current guidelines. Funded largely by the National Heart, Lung, and Blood Institute (NHLBI), part of NIH, the study results were published in the American Journal of Respiratory and Critical Care Medicine.
The gut microbiota is a key player in multiple facets of human health, influencing disease development and prevention. An interdisciplinary collaboration is needed to unravel its complexities and to finding potential avenues for therapeutic interventions.
Explore the following trending articles in Frontiers in Cellular and Infection Microbiology and Frontiers in Gastroenterology.
CAR T-cell (chimeric antigen receptor) therapy, a promising form of immunotherapy, involves reprogramming the patient’s T cells to enhance their ability to identify and combat antigens on the surface of cancer cells.
However, this therapy, which is currently approved for the treatment of leukemia and lymphoma, has a significant downside. During the process of destroying cancer cells, many of the engineered T cells get contaminated with residual cancer antigens, leading them to attack fellow T cells. This eventually results in a decrease in the body’s population of cancer-fighting cells, opening the door for a recurrence of cancer.
A new Yale study, however, has identified a way to tame the self-destructive tendencies of these killer T cells. Simply fusing a molecular tail onto the engineered T cells used in therapy, researchers say, can inhibit their proclivity to attack each other. The study was published July 27 in the journal Nature Immunology.
