MachineLearning clinical prediction models fail to generalize across trial data, a new Science study finds. The results “require reexamination of the practical challenges that precision medicine is facing.” Learn more in a new Science Perspective:
The prediction of individual treatment responses with machine learning faces hurdles.
Frederike H. Petzschner [email protected] Authors Info & Affiliations
Science.
https://www.news-medical.net/news/20240123/New-study-reveals…tment.aspx ASMicrobiology
In a recent study published in the American Society for Microbiology, researchers developed a novel rabbit infection model to investigate meropenem’s resistance development potential and antibacterial efficacy.
Study: Molecular pharmacodynamics of meropenem for nosocomial pneumonia caused by Pseudomonas aeruginosa. Image Credit: Sam Rana/Shutterstock.com.
Background
The article repeats itself a bit but there’s some good parts about an exoskeleton, advanced algorithm and bipedal robots and prosthetics. It’ll basically apply to those future industries.
We typically don’t think about it whilst doing it, but walking is a complicated task. Controlled by our nervous system, our bones, joints, muscles, tendons, ligaments and other connective tissues (i.e., the musculoskeletal system) must move in coordination and respond to unexpected changes or disturbances at varying speeds in a highly efficient manner. Replicating this in robotic technologies is no small feat.
Now, a research group from Tohoku University Graduate School of Engineering has replicated human-like variable speed walking using a musculoskeletal model – one steered by a reflex control method reflective of the human nervous system. This breakthrough in biomechanics and robotics sets a new benchmark in understanding human movement and paves the way for innovative robotic technologies.
Study finds measuring levels of a protein could be just as good at detecting disease as lumbar punctures.
Three years old boy with reassuring development had presented to the Pediatric Neurology clinic with a referral due to a large head. Occipito-frontal circumference was more than 97th centile with an unremarkable neurological examination. MRI brain exhibited an acute on chronic large right frontoparietal subdural hematoma with prominent mass effect. Consequentially, the hematoma was evacuated by the neurosurgeon. Postoperative recovery stayed satisfactory. Hematology workup showed normal coagulation and clotting factors levels. Whole exome sequencing (WES) study revealed heterozygous variant c.5187G>A p.(Trp1729• in gene FBN1 — pathogenic for Marfan syndrome. However, this variant has not yet been reported in association with cerebral arteritis/intracerebral bleed. On follow-up, the child remained asymptomatic clinically with static head size.
By Chuck Brooks
Computing paradigms as we know them will exponentially change when artificial intelligence is combined with classical, biological, chemical, and quantum computing. Artificial intelligence might guide and enhance quantum computing, run in a 5G or 6G environment, facilitate the Internet of Things, and stimulate materials science, biotech, genomics, and the metaverse.
Computers that can execute more than a quadrillion calculations per second should be available within the next ten years. We will also rely on clever computing software solutions to automate knowledge labor. Artificial intelligence technologies that improve cognitive performance across all envisioned industry verticals will support our future computing.
Advanced computing has a fascinating and mind-blowing future. It will include computers that can communicate via lightwave transmission, function as a human-machine interface, and self-assemble and teach themselves thanks to artificial intelligence. One day, computers might have sentience.
The new virus is thought to eliminate dormant bacteria, providing significant hope against the predicted 10 million annual deaths expected by 2050.
When bacteria encounter a lack of nutrients or experience stress induced by the antibiotics, they undergo a regulated shutdown of their metabolism, entering a dormant resting state.
This ETH Zurich-led discovery significantly advances addressing the global superbug crisis.
The researchers state that this newly identified virus can effectively attack these dormant bacteria when paired with drugs.
Posted in biotech/medical, education, health
See why new discoveries about water on Mars and water on the Moon are great news for the future of space settlement!
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The study hypothesizes that ‘pre-digested’ foods contributed to the development of larger brains. The large, capable human brain is a marvel of evolution, but how it evolved from a smaller primate brain into the creative, complex organ of today is a mystery. Scientists can pinpoint when our evolutionary ancestors evolved larger brains, which roughly tripled in size as human ancestors evolved from the bipedal primates known as Australopithecines.
