Lifeboat Foundation

Tap through to read how, for almost 30 years, a world-leading gait analysis laboratory at The Royal Children’s Hospital, Melbourne has helped children with cerebral palsy receive life-changing treatments → unimelb.me/45ez4RT

For almost 30 years, a world-leading gait analysis laboratory at The Royal Children’s Hospital in Melbourne has helped children with cerebral palsy receive life-changing treatments.

When Professor Kerr Graham arrived in Australia to introduce gait analysis technology to help manage children with cerebral palsy, some medical professionals were sceptical. An accomplished orthopaedic surgeon who had trained in Ireland, London and Toronto, Professor Graham had witnessed firsthand the dramatic potential of gait analysis to improve the lives of children with cerebral palsy.

Continue reading “Helping children with cerebral palsy put their best foot forward” »

All medical breakthroughs have to start somewhere, and Intellia Therapeutics is ready to show the world the first-in-human gene editing data that could be the start of a | Interim results are in for Intellia and partner Regeneron’s in vivo CRISPR/Cas9 genome editing candidate, NTLA-2001, in patients with transthyretin (ATTR) amyloidosis: and the numbers look good. This is the first time gene editing has been proven to work in humans, which “opens up a whole new area of therapies for patients that wasn’t there.”

Scientists have discovered new insights into how our brain stores episodic memories—a type of long-term, conscious memory of a previous experience—that could be critical to the development of new neuroprosthetic devices to help patients with memory problems, like Alzheimer’s disease and dementia.

The new study—led by the University of Glasgow, in collaboration with the University of Birmingham and University of Erlangen—used special electrodes, implanted directly into the brains of epilepsy patients requiring surgery, to allow scientists to observe the activity of individual neurons in the hippocampus region of the brain.

The hippocampus is a challenging area to study, due to its location deep within the brain, yet this area is critical for our memory, acting as the librarian to the memory library in our brain.

A process of surgically joining the circulatory systems of a young and old mouse has been found to slow aging at a cellular level and extend the older animal’s life by as much as 10%.

Recently published in Nature Aging, a study led by researchers from Duke Health discovered the longer the animals shared circulation, the longer the anti-aging benefits lasted once the two were no longer connected.

The findings suggest that the young benefit from a cocktail of components and chemicals in their blood that contribute to vitality, and these factors could potentially be isolated as therapies to speed healing, rejuvenate the body, and add years to an older individual’s life.

A recent study reports something strange: When mice with Alzheimer’s disease inhale menthol, their cognitive abilities improve. It seems the chemical compound can stop some of the damage done to the brain that’s usually associated with the disease.

In particular, researchers noticed a reduction in the interleukin-1-beta (IL-1β) protein, which helps to regulate the body’s inflammatory response – a response that can offer natural protection but one that leads to harm when it’s not controlled properly.

The team behind the study, which was published in April 2023, says it shows the potential for particular smells to be used as therapies for Alzheimer’s. If we can figure out which odors cause which brain and immune system responses, we can harness them to improve health.

This isn’t a new discovery but something we’ll have to deal with in some places. I’ve actually drank noxious tap water and got really sick.

Most Americans take it for granted that the water that comes out of their taps is clean and safe to drink.

But a new study published by a University of New Mexico scientist with colleagues from across the U.S. warns that water from many wells and community water systems contains unsafe levels of toxic contaminants, exposing millions to health risks, including cancer.

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The 2023 Nobel Prize in Chemistry was awarded to three scientists who discovered and developed quantum dots, which are very small particles that can change color depending on their size. Quantum dots are tiny particles of a special kind of material called a semiconductor. They are so small that they behave differently from normal materials. They can absorb and emit light of different colors depending on their size and shape.

You can think of quantum dots as artificial atoms that can be made in a lab! They have some of the same properties as atoms, such as having discrete energy levels (meaning they can only exist in certain distinct energy states, and they cannot have energy values between these specific levels) and being able to form molecules with other quantum dots. But they also have some unique features that make them useful for many applications, such as displays, solar cells, sensors, and medicine, which I shall discuss later in this story!

To grasp the workings of quantum dots, a bit of quantum mechanics knowledge comes in handy. Quantum mechanics teaches us that these tiny entities can possess only specific amounts of energy, and they transition between these energy levels by absorbing or emitting light. The energy of this light is determined by the difference in energy levels. In typical materials like metals or plastics, energy levels are closely packed, forming continuous bands where electrons can move freely, resulting in less specific light absorption or emission. However, in semiconductors like silicon or cadmium selenide, there’s a gap between these bands known as the “band gap.” Electrons can only jump from one band to another by interacting with light having an energy level that precisely matches the band gap, making semiconductors valuable for creating devices like transistors and LEDs.

This is just Episode 1 of 10 in the powerful Radical Remission docuseries. To learn more, visit: http://radicalremissiondocuseries.com/

In Radical Remission, you’ll meet 21 amazing survivors who healed against all odds by taking control of their healing process, plus dozens of world-renowned scientists, researchers, and doctors who speak to the scientific validity of what the survivors are saying.

From LED lights to medical imaging, quantum dots have many varied applications.

The creation of quantum dots earned its developers the Nobel Prize in Chemistry 2023, an invention that could have also been a contender for the Physics Prize. These tiny elements of nanotechnology, which are so miniature that their size dictates their properties, are today used in many useful and practical applications and have even been reported to direct surgeons as they tackle tricky tumor tissue.

Nobel Prize/Twitter.

Continue reading “Chemistry Nobel Prize goes to quantum dots that guide surgeons” »