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Category: biotech/medical – Page 395

Everyone has BRCA1 and BRCA2 genes, but mutations in these genes—which can be inherited—increase the risk of breast and .

The study found that the in breast tissue of healthy women carrying BRCA1 or BRCA2 gene mutations show signs of malfunction known as exhaustion. This suggests that the immune cells can’t clear out damaged breast cells, which can eventually develop into breast cancer.

This is the first time that exhausted immune cells have been reported in non-cancerous breast tissues at such scale—normally these cells are only found in late-stage tumors. The results raise the possibility of using existing immunotherapy drugs as early intervention to prevent breast cancer developing, in carriers of BRCA1 and BRCA2 gene mutations.

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In a new study, AI processed text from health histories and neurologic examinations to locate lesions in the brain. The study, which looked specifically at the large language model called generative pre-trained transformer 4 (GPT-4), is published in the online issue of Neurology Clinical Practice.

A can cause long-term disability or even death. Knowing where a stroke has occurred in the brain helps predict long-term effects such as problems with speech and language or a person’s ability to move part of their body. It can also help determine the and a person’s overall prognosis.

Damage to the from a stroke is called a lesion. A neurologic exam can help locate , when paired with a review of a person’s health history. The exam involves symptom evaluation and thinking and memory tests. People with stroke often have brain scans to locate lesions.

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On 28 March it’s the 60th anniversary of the discovery of Epstein-Barr virus, the most common viral infection in humans. The virus was first discovered in association with a rare type of cancer located in Africa, but is now understood to be implicated in 1% of cancers, as well as the autoimmune disease multiple sclerosis. Ian Sample meets Lawrence Young, professor of molecular oncology at Warwick Medical School, to hear the story of this virus, and how it might help us prevent and treat cancer and other illnesses.

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On social media, a bizarre trend seems to be emerging: surprise pregnancies when taking the diabetes drug Ozempic and its sister weight loss shot Wegovy.

As People reports, there are a few reasons why people might be getting pregnant unexpectedly when taking these semaglutide-based injectable drugs.

For one thing, Dr. Iman Saleh — an obstetrician, gynecologist, and obesity medicine doctor at New York’s Northwell Health system — tells People that through a roundabout mechanism, the weight people lose on these drugs may be making them more fertile.

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“We hope our work will contribute to informed decisions regarding regulatory measures or behavioral interventions to minimize chemical exposure and protect human health,” Tesar said in a statement.

1.8 million. That’s how many people globally have multiple sclerosis, according to the World Health Organization. The agency also found around one in 100 children worldwide have been diagnosed with autism.

“Rigorous safety tests are in place for human health that are evaluated by [the] U.S. Environmental Protection Agency for approval and compliance with all regulatory guidelines,” Brian Sansoni, senior vice president for Communications, Outreach and Membership for the American Cleaning Institute, told Forbes. The ACI represents top cleaning product manufacturers like the Clorox Company and Procter & Gamble. “ACI member company manufacturers make product safety a top priority.” Quats have been known to be effective at killing bacteria, germs, viruses and mold. “The use of cleaning products, disinfectants and their chemistries contribute to public health in homes, schools, healthcare settings and communities every single day,” the ACI said.

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