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Category: biotech/medical – Page 382

A recent study at MIT has debunked the effectiveness of a new MRI method called DIANA, which was initially thought to directly detect neural activity.

Instead, the signals detected were found to be artifacts produced by the imaging process itself, highlighting the complexities and challenges in developing accurate neuroimaging techniques.

According to scientists at MIT’s McGovern Institute for Brain Research, a new way of imaging the brain with magnetic resonance imaging (MRI) does not directly detect neural activity as originally reported.

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Scientists at Kyoto University Hospital will conduct the first human trial of the drug from September 2024 to August 2025. In tests on ferrets and mice, the drug worked with no notable side effects, Popular Mechanics reported.

The drug will be used on 30 men between 30–64 who are missing at least one molar. From there, researchers will expand the study to those with partial edentulism, or those missing one to five permanent teeth.

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Centenarians have become the fastest-growing demographic group in the world, with numbers approximately doubling every 10 years since the 1970s.

Many researchers have sought out the factors and contributors that determine a long and healthy life. The dissolution isn’t new either, with Plato and Aristotle writing about the ageing process over 2,300 years ago.

Understanding what is behind living a longer life involves unravelling the complex interplay of genetic predisposition and lifestyle factors and how they interact.

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Good health depends on a healthy diet and sufficient exercise and sleep. There are clear associations among these components; for example, good nutrition provides energy for exercise, and many people report that getting enough exercise is important to their ability to get enough sleep. So how might nutrition affect sleep?

A new study looks at the connection between fruit and vegetable intake and sleep duration. The research, by a team from Finland’s University of Helsinki, National Institute for Health and Welfare, and Turku University of Applied Sciences, is published in Frontiers in Nutrition.

Why sleep is important and how it works Sleep gives our bodies the chance to rest and recover from wakeful activity. Our hearts, blood vessels, muscles, cells, immune systems, cognitive abilities, and memory-making abilities depend on regular, healthy sleep for optimal functioning, and a 2019 study suggests that sleep is important for repairing DNA damage that occurs during wakefulness.

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Scientists in Japan say they have reversed the signs of Alzheimer’s disease in lab mice by restoring the healthy function of synapses, critical parts of neurons that shoot chemical messages to other neurons.

The secret was developing a synthetic peptide, a small package of amino acids — a mini-protein, if you will — and injecting it up the nostrils of the mice, in an experiment they detailed in a study published in the journal Brain Research.

Needless to say, mice are very different from humans. But if the treatment successfully survives the gauntlet of clinical studies with human participants, it could potentially lead to a new treatment for Alzheimer’s disease, a tragic degenerative condition that burdens tens of millions of people around the world.

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Researchers at the University of Utah Health have discovered that “time cells” in mice are crucial for learning tasks where timing is critical. These cells change their firing patterns as mice learn to distinguish between timed events, suggesting a role beyond just measuring time. This finding could help in the early detection of neurodegenerative diseases like Alzheimer’s by highlighting the importance of the medial entorhinal cortex (MEC), which is among the first brain regions affected by such diseases.

Researchers at the University of Utah Health found that “time cells” in mice adapt to learning timed tasks, a discovery that could aid early Alzheimer’s detection by monitoring changes in a key brain region.

Our perception of time is crucial to our interaction with and understanding of the world around us. Whether we’re engaging in a conversation or driving a car, we need to remember and gauge the duration of events—a complex but largely unconscious calculation running constantly beneath the surface of our thoughts.

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