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The Major Mouse Testing Program

Overview.

What is the MMTP? The MMTP is an ambitious project, designed to radically speed up the rate of progress in the field of regenerative medicine and aging research.

The project is the brainchild of our parent organisation, The International Longevity Alliance, a nonprofit foundation for science advocacy and research. The testing and discovery of compounds and treatments to delay or stop the processes of aging is a slow affair, with very few high quality, high impact studies conducted each year.

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New Wireless Neural Implant Transmits Brain Signals to Prosthetic Limbs

A new chip designed for the brain is now wireless. Now that it is no longer connected using wires, will it compromise its accuracy?

The Nanyang Technological University in Singapore has developed a smart chip that can be used for neural implants in order to wirelessly transmit brain signals to the rest of the body with 95% accuracy. These neural implants, and the data that they register, are expected to help curtail symptoms of diseases like Parkinson’s, and they could also help paraplegic patients move their prosthetic limbs.

For operations, external devices can use the the 5mm by 5mm chip to receive and analyze data before sending back important details, instead of sending the entire data stream all at once. This drastically decreases its power consumption, making the tech far more viable.

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Scientists Have Created Miniature Versions of the Human Brain Using Skin Cells

Researchers have developed a functioning miniature replica of the human brain, composed of neurons and glial cells, to help study and better understand neurological diseases.

A tiny ball of brain cells may help researchers alleviate or treat neurological diseases.

These small cellular balls act like miniature versions of the human brain, mimicking various aspects of the actual brain that include sending pulses of electric signals akin to what happens in a thinking mind. This research was reported at the annual meeting of the American Association for the Advancement of Science in Washington.

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GBM Treatment Discoveries: Why Select Drugs Might not Work

New insights on GBM resistance markers.


A research team, with the participation of the University of Granada (UGR), has made some progress in determining the causes for glioblastoma multiforme (GBM), one of the most aggressive brain tumors known, to be resistant to the drugs currently used, which is one of the main limitations of its treatment. The results have been recently published in two articles in PlosOne magazine.

The researchers have proven that proteoglycans (the cells’ structural elements), called decorin (DCN) and lumican (LUM), could be decisive in the behavior and development of a resistance to the drugs used for treating glioblastoma multiforme, such as temozolamide (TMZ). In the other hand, they have laid bare that the inhibition of the transcription of some of the sub-units belonging to the mismatch-repair (MMR) complex, a system that analyzes and repairs DNA, could be responsible of the failure of current therapies against this kind of tumor.

This is a scientific breakthrough that could be useful for the search of new resistance markers in GBM as well as for the development of new therapeutic strategies which avoid the resistance to drugs that these tumors possess.

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Brain scan for artificial intelligence shows how software thinks

Neural networks have become enormously successful – but we often don’t know how or why they work. Now, computer scientists are starting to peer inside their artificial minds.

A PENNY for ’em? Knowing what someone is thinking is crucial for understanding their behaviour. It’s the same with artificial intelligences. A new technique for taking snapshots of neural networks as they crunch through a problem will help us fathom how they work, leading to AIs that work better – and are more trustworthy.

In the last few years, deep-learning algorithms built on neural networks – multiple layers of interconnected artificial neurons – have driven breakthroughs in many areas of artificial intelligence, including natural language processing, image recognition, medical diagnoses and beating a professional human player at the game Go.

The trouble is that we don’t always know how they do it. A deep-learning system is a black box, says Nir Ben Zrihem at the Israel Institute of Technology in Haifa. “If it works, great. If it doesn’t, you’re screwed.”

Neural networks are more than the sum of their parts. They are built from many very simple components – the artificial neurons. “You can’t point to a specific area in the network and say all of the intelligence resides there,” says Zrihem. But the complexity of the connections means that it can be impossible to retrace the steps a deep-learning algorithm took to reach a given result. In such cases, the machine acts as an oracle and its results are taken on trust.

To address this, Zrihem and his colleagues created images of deep learning in action. The technique, they say, is like an fMRI for computers, capturing an algorithm’s activity as it works through a problem. The images allow the researchers to track different stages of the neural network’s progress, including dead ends.

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Welcome to Major Mouse Testing Project

The MMTP needs your support!

Have you ever considered your destiny may depend upon, you personally? And beyond that, have you considered the destiny of many others may depend upon your actions? People who have changed the world, didn’t have any doubts that the future depended on their actions. Scientists, businessmen and famous public figures didn’t wait until someone did something important for the world. They took responsibility for what was happening around and acted, despite all the difficulties. Are you ready to become such a person? Maybe you too have always wanted to make a significant difference, but didn’t know where to begin? So spend a moment to read the information below.

Today there is a unique project being prepared by a group of scientists, activists and other like minded people from many countries. A project which will give us the opportunity to rescue millions of people from future suffering. The project brings the fight against aging to a global level. Each day people suffer and die from the many diseases associated with aging. Researchers worldwide are engaged in a valiant effort to save countless lives in the near future.

We are currently preparing the first stage of the MMTP project — to test combinations of geroprotectors on mice. The results of this research will be available to the entire scientific community. It’s a big step in this work against the most serious enemy of mankind — aging and its related diseases. And now our project urgently needs the help of motivated individuals. We’re looking for volunteers who are ready to put in the time and effort, to make a future without aging a reality that much sooner.

We are therefore looking for people with experience in different fields. Our project is greatly in need of the following activists:

Copywriters. Are you able to state your thoughts on set subject well? Are you interested in discoveries in the field of regenerative medicine? Do you have a little time and a lot of desire to participate in something really important? If so we really need you!

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