Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 2,906

Artificial Vision, Artificial Retina, Optogenetics, José Alain Sahel MD, CMU RI Seminar

For those interested in life extension and bionic / cyborg type enhancements, this CMU Robotics Institute Seminar gives an overview of the background and current developments in artificial vision. José Alain Sahel MD is a world leading ophthalmologist with a lengthy bio and numerous honors and appointments.

In the future, if you’re going blind, these sight restoration technologies may be used to remediate your vision loss.

Three major ideas are covered. 1) Implanting arrays of tiny 3-color LEDs under a failed retina to stimulate still-okay cells, and 2) using gene therapy to express a novel photoreceptor, borrowed from algae, to restore a form of sight to failed cells. These can be done together. Lots of studies in mice, primates, and humans. Some coverage is also given to 3) directly implanting electronics in the brain to send complete images to vision centers, but this is still at an early stage.

None of this is anywhere near total restoration. The patients can make out a few words for the first time. And unlike normal vision, the range of light intensity levels remains very narrow. But obviously it’s much better than nothing and will get better over time.

As a point of humor, he tells the story of one of his blind patients who totally redesigned one of his experiments for him.

Next-Gen Spacesuits and the Commercial Space Industry

By Kelsey Tollefson | Executive Editor John Lenker

Space suits are iconic—a visual metaphor for the excitement of the original Space Race and mankind’s first forays off our planet. While many still associate space travel with the puffy white suits worn by astronauts in the 1960s, a proliferation of sci-fi movies in the intervening decades has opened our imaginations to a wider array of possibilities. Far from being fantastical, these new spacesuits reflect an evolved understanding of the considerations involved in protecting the human body from harsh environments outside Earth’s atmosphere.

Related: Under pressure: the past, present, and future spacesuit market.

In a possible step forward for gene therapy, researchers made mice glow like fireflies

The old joke in the US Natl. Labs is if you worked at ORNL, you glowed at night. Looks like DARPA has found a safer way to do it.

Timothy Blake, a postdoctoral fellow in the Waymouth lab, was hard at work on a fantastical interdisciplinary experiment. He and his fellow researchers were refining compounds that would carry instructions for assembling the protein that makes fireflies light up and deliver them into the cells of an anesthetized mouse. If their technique worked, the mouse would glow in the dark.

Not only did the mouse glow, but it also later woke up and ran around, completely unaware of the complex series of events that had just taken place within its body. Blake said it was the most exciting day of his life.

This success, the topic of a recent paper in Proceedings of the National Academy of Sciences, could mark a significant step forward for . It’s hard enough getting these instructions, called messenger RNA (mRNA), physically into a cell. It’s another hurdle altogether for the cell to actually use them to make a protein. If the technique works in people, it could provide a new way of inserting therapeutic proteins into diseased cells.

Robots could be injected into the body to fight cancer

We have stated this for a while; time to make it commercially available.

Our bodies are full of immune cells that circle around the blood, ready to see off any invaders.

And soon they could be getting a helping hand from tiny disease-fighting robots.

Scientists have created an army of magnetically-controlled robots which they say could help our bodies fight off diseases such as cancer.

Study finds targeting biological clock in cells slows cancer

Nice. My friend Alex Zhavoronkov will appreciate this article.

Feb. 16 (UPI) — Researchers at McGill University in Montreal have found that targeting the internal circadian or biological clock of cancer cells can affect growth.

Most cells in the human body have an internal clock that sets a rhythm for activities of organs depending on the time of day. However, this internal clock in cancer cells does not function at all or malfunctions.

“There were indications suggesting that the malfunctioning clock contributed to rapid tumor growth, but this had never been demonstrated,” Nicolas Cermakian, a professor in the department of psychiatry at McGill University, director of the Laboratory of Molecular Chronobiology at the Douglas Mental Health University Institute and author of the study, said in a press release. “Thanks to the use of a chemical or a thermic treatment, we succeeded in ‘repairing’ these cells’ clock and restoring it to its normal functioning. In these conditions, tumor growth drops nearly in half.”

All inherited diseases including cancer ‘could be cured in the next 20 years’

Definitely yes on gene mutations; however, those where the disease has already appeared, or cancer that has occurred before will require another form of eradication/ prevention. And, that is where Quantum Biosystem technology will be effective in eliminating disease.

ALL inherited diseases could be cured within 20 years, a leading British expert claims.

It includes eradicating life-limiting conditions such as cystic fibrosis and Huntington’s disease.

Company Claims Brain Transplants Could Bring Back the Dead by 2045

Not too shock by this given other transplant patient’s stories of memories, etc.

1 brains
There are a lot of outrageous claims being made within the halls of neuroscience and artificial intelligence. Whether exaggerations, wishful thinking, the dreams of the egocentric and megalomaniacal to be immortal, or just drumming up funding for a never-ending round of “scientific investigation,” the year 2045 seems to always be cited as a target date.

Ray Kurzweil popularized the notion of The Singularity – the threshold when computing power would match or exceed the human brain and human biological systems – in his 2006 book The Singularity is Near: When Humans Transcend Biology. In that book, and subsequent articles, he theorized that 2045 would be the far end of when we could expect full integration of human and machine that would create immortality.

So far there have been indications that we are indeed proceeding in this direction. Beyond the gadgets we all use to augment our intelligence, each day seems to offer a new medical development that reads more like science fiction than reality. Just the other day there was an article in The Seattle Times that a new type of flexible brain implant could enable the paralyzed to walk again. We have robotic prostheses, humanoid robots, artificial human skin, and a range of nanotechnology applications used in medicine and the military that are quickly redefining life and nature itself. In fact, it’s been proclaimed by scientists that the era of cyborgs has begun.

Aubrey de Grey — A Post-Aging Planet

A great Q&A, especially with the deathists that crop up.

Website ► http://sens.org
YouTube ► https://www.youtube.com/user/SENSFVideo
Facebook ► https://www.facebook.com/sensf
Twitter ► https://twitter.com/senstweet

SENS Research Foundation is a 501©(3) public charity that is transforming the way the world researches and treats age-related disease.

“At SENS Research Foundation, we believe that a world free of age-related disease is possible. That’s why we’re funding work at universities across the world and at our own Research Center in Mountain View, CA.

Our research emphasizes the application of regenerative medicine to age-related disease, with the intent of repairing underlying damage to the body’s tissues, cells, and molecules. Our goal is to help build the industry that will cure the diseases of aging. ”

Continue reading “Aubrey de Grey — A Post-Aging Planet” | >

/* */