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Doctors Fighting Brain Cancer

Glioblastoma is one of the most common and aggressive forms of brain cancer, and it is particularly difficult to treat. Now, researchers from the University of Pennsylvania School of Medicine have come up with a new approach to treatment for the disease, by growing organoids based on a patient’s own tumor to find the most effective treatments. Digital Trends spoke to senior author Dr. Donald O’Rourke to learn more.

The technique uses mini-brains — pea-sized organoids grown from stem cells which recreate features of full-scale brains. The mini-brains are similar enough to real brains that they can be used for testing out medical treatments to see how a full-sized brain would respond.

The breakthrough in this research is regarding treatment individualization. One of the challenges of treating a complex disease like brain cancer is that different people respond in different ways to the various treatment options available. After surgery has been performed to remove a tumor, doctors typically begin further treatment using radiation or chemotherapy around one month later. That means there isn’t always time to use perform genetic analysis to see which treatment might be best suited for a particular patient — the doctors need to know what will work and start further treatment as soon as possible.

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MIT Scientists Can Look at Your Insides From a Distance

Scientists have developed a system of lasers that can probe inside the human body, much like an ultrasound, but from a distance.

The system can accurately image what’s going on inside a person’s body up to a depth of about six centimeters, according to an MIT press release. While that may not seem like much, it’s still an important first step in removing physical contact from ultrasound scans, as that can sometimes introduce variability in a doctor’s readings.

The system, described in research published in the journal Light: Science & Applications on Friday, uses two lasers: one to generate sound waves that bounce around inside the patient’s body, and the second to detect them as they reflect back.

Scientists race to use zero gravity to kill the worst cancers

The device has allowed Chou’s team to investigate how microgravity affects different diseases. The scientists report it has been tremendously effective so far in eliminating cancer cells.

“When placed in a microgravity environment, 80 to 90 per cent of the cells in the four different cancer types we tested – ovarian, breast, nose and lung – were disabled,” said Chou.

Normally, these are the hardest cancers to fight. Chou’s experiments, without using any drugs, managed to either kill such cells or make them “float off because they can no longer hold on.”

Scientists Have ‘Cleared’ Alzheimer’s Plaque From Mice Using Only Light And Sound

Clumps of harmful proteins that interfere with brain functions have been partially cleared in mice using nothing but light and sound.

Research led by MIT earlier this year found strobe lights and a low pitched buzz can be used to recreate brain waves lost in the disease, which in turn remove plaque and improve cognitive function in mice engineered to display Alzheimer’s-like behaviour.

It’s a little like using light and sound to trigger their own brain waves to help fight the disease.

Israel’s alpha radiation treatment shows tumor shrinkage in 100% of cases

The second thing to mention is that in many instances, we actually have cracked it, at least medically. There are endless cutting-edge treatments being deployed as we speak, and endless additional cutting-edge research projects being conducted. There are new breakthroughs all the time, much of which are awaiting FDA approval, but one thing many of these treatments and cures have in common is that they are developed in a tiny country smaller than New Jersey that happens to be located in perhaps the worst neighborhood on Earth. When it comes to cancer research, Israel leads the way.

Finally, the last time I wrote about cutting-edge cancer treatments, I was contacted by a close friend who is a leading oncologist. He pointed out that a disclaimer is very much necessary when I write these articles. The last thing oncologists need is for their patients to think there is some magical solution here and show up to their appointments with a cut-out of an article. In fact, the last thing a cancer patient needs is false hope.

So the disclaimer is that this company is in the clinical trial phase, and if all goes according to plan, tumors might be much more manageable and treatable than they are today, but a lot has to happen before we get there.

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