Boston biopharma startup resTORbio Inc. is revamping its pipeline to focus on cancer cell therapies through a reverse-merger.
Category: biotech/medical – Page 2,633
Blood Pressure Drugs Don’t Increase Coronavirus Risk, Studies Find
Both studies were based on reviewing patients’ records, which does not provide evidence as strong as the results of controlled clinical trials, where patients are picked at random to take one treatment or another 🙄.
People taking widely used medicines did not face higher rates of infection or more severe illness, new research indicates.
Aging and diet lead to proteome changes in the intestinal epithelium
The small intestine is one of the most important interfaces between the environment and our body. It is responsible for nutrient absorption but also forms a barrier against potentially harmful environmental cues. A research team, led by researchers from the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena, Germany, investigated the effects of aging and diet on the intestinal epithelium of young and old mice. They were able to show region-specific effects on the proteome and age-related impairments in adaptation to nutrient availability. Their results provide a complete picture of the spatial organization of the small intestine proteome in the mouse. The results were published in the journal Cell Reports.
The small intestine (SI) is one of the most important interfaces between the environment and our body. It has two major functions: it is responsible for absorbing nutrients from the food we eat and functions as a barrier to restrict the entry of harmful substances. The SI is a highly adaptive and dynamic organ, as it adapts to changes in nutrient intake or diet. The intestinal epithelium undergoes a process of continuous renewal, every 3–5 days.
Effects of aging and diet on the small intestine have already been investigated. It is known that aging leads to reduced absorption of nutrients by the epithelium thus contributing to malnutrition in elderly people. In addition, anatomical differences between different regions of the SI are well known, but so far, region-specific effects of aging and diet on the set of proteins that compose the intestinal epithelium had not been investigated.
MigVax: Israeli COVID-19 vaccine closer to trials
Well, every dark cloud does have a silver lining. Out of nearly three million confirmed cases of coronavirus, 1.77 million are mild cases, and more than 807,050 people have recovered as of the time of my writing this.
I think it is fair to say that a vast majority of human beings on planet Earth have one question in their minds: When will we have an actual vaccine?
Well, I have some good news.
New molecular insights into how gut bacteria influences memory
New research from an international team of scientists has tracked a compelling series of connections between the gut microbiome and memory. Using a novel mouse model engineered to simulate the genetic diversity of a human population, the study illustrates how genetics can influence memory via bacterial metabolites produced in the gut.
Over the past few years there has been significant research interest in the relationship between memory, cognition and the gut microbiome. While certain families of bacteria that live in our gut have been implicated in memory function, this new study set out to investigate the connection from a different angle, starting with the role genetics play in this relationship.
“To know if a microbial molecule influenced memory, we needed to understand the interaction between genetics and the microbiome,” explains co-corresponding author on the study, Antoine Snijders.
Top Cleric at Iran’s Southern Khorasan Province, Alireza Ebadi: Humanity Must Fight the “Two-Legged Viruses” of Western Liberalism, Which Are Even Worse than the Coronavirus
Islamic religious scientist points out a hidden existential threat, worse even than the SARS-CoV-2 virus: two-legged viruses that spread liberal democracy.
Iranian scholar Alireza Ebadi, Supreme Leader Ayatollah Ali Khamenei’s representative in the Southern Khorasan Province, said in a lecture that aired on Khorasan Jonoobi TV (Iran) on April 10, 2020 that the “virus” of Western liberal democracy is even worse than the coronavirus since it has caused the deaths and displacement of millions of people, two world wars, coups in various countries such as Iraq, the spread of cholera in Yemen, and Western intervention in Syria, Afghanistan, India, Pakistan, and elsewhere. Ebadi expressed hope that once humanity defeats the “pest” of the coronavirus, it will “make sure the greatest pests of all do not escape.” He added: “May God [save] humanity from [the] two-legged viruses.”
