A proton beam can kill cancer cells, and the accelerators used for treatment are always the circular kind. Linear accelerators (“linacs”) allow more control of the beam; for example, the energy can be varied rapidly to match a patient’s breathing. But linacs take up a lot of space. Now researchers propose a design that could fit in a room 10 m x 20 m, potentially making linacs practical for patient therapy. Research from CERN.
While many scientists have shied away from explicitly political actions in recent decades, the community throughout history has spoken publicly on a wide variety of social, technological and ideological issues.
That has included everything from opposing fascism, nuclear proliferation and the Vietnam War to sitting on government panels that advise elected leaders on stem-cell research involving human embryos.
In U.S. history, scientists have been vocal about fascism, nuclear proliferation, the Vietnam War, stem cells and more.
Many artificial organs are being developed as an alternative to donated organs, which are only temporary solutions that require the recipients to maintain a lifetime regiment of medications. With recent advancements in biomedical technologies, the time may be coming when those who require transplants no longer need to wait on donation lists to replace organs like kidneys and blood vessels. And now, scientists have added the thymus to the list of body parts we can artificially simulate.
The thymus is a gland that is essential to your immune system. T cells, a type of white blood cell that helps to get rid of viruses, bacterial infections, and cancer cells, mature within this gland. When people get sick (or as they age), the thymus becomes worse at its job. In some cases, people with different types of cancer are not getting the biological support and help they need from their T cells.
A team of Australian researchers have discovered a new method to fight colon and stomach cancer. Their technique involves inhibiting a protein that cancer cells use to rapidly reproduce.
“Our discovery could potentially offer a new and complementary approach to chemotherapy and immunotherapy as options for treating gastrointestinal cancers,” said professor Matthias Ernst, scientific director at the Olivia Newton-John Cancer Research Institute, in a statement.
Hematopoietic cell kinase (HCK) is an enzyme that helps stem cells become blood cells – hematopoietic cells are the stem cells that all blood cells start as. One type of blood cells that HCK helps to code are macrophages, “big eater” white blood cells whose job is to consume and destroy anything that impedes healthy blood, such as cellular debris, microbes and cancer cells.
DNA protects itself from damage naturally, and scientists are hoping to gain insight into how the process works. When DNA is bathed in ultraviolet light, it can eject a single proton from a hydrogen atom to rid itself of excess energy, ensuring other chemical bonds remain intact. This protective mechanism is called an excited state proton transfer, and it is the focus of new research by a team of scientists.
The researchers used the Linac Coherent Light Source (LCLS) at the SLAC National Accelerator Laboratory to generate X-ray laser pulses capable of probing the nitrogen molecule — in the simple molecule 2-thiopyridone — for quadrillionths of a second. The short period of time matters because when molecules are exposed to this kind of light they react incredibly quickly. The brightness of the light is equally important, because only very brilliant illumination renders these ultrafast changes visible to the researchers.
“These re-engineered organisms will change our lives over the coming years, leading to cheaper drugs, ‘green’ means to fuel our cars and targeted therapies for attacking ‘superbugs’ and diseases, such as cancer,” wrote Drs. Ahmad Khalil and James Collins at Boston University, who were not involved in the study.
Our brains are often compared to computers, but in truth, the billions of cells in our bodies may be a better analogy. The squishy sacks of goop may seem a far cry from rigid chips and bundled wires, but cells are experts at taking inputs, running them through a complicated series of logic gates and producing the desired programmed output.
Take beta cells in the pancreas, which manufacture and store insulin. If they detect a large spike in blood sugar, then they release insulin; else they don’t. Each cell adheres to commands like these, allowing us—the organism—to operate normally.
This circuit-like nature of cellular operations is not just a handy metaphor. About 50 years ago, scientists began wondering: what if we could hijack the machinery behind these algorithms and reprogram the cells to do whatever we want?
