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Newly identified cellular trash removal program helps create new neurons

Summary: Vimentin, a cellular filament, helps neural stem cells to clear damaged and clumped proteins, assisting in neurogenesis.

Source: University of Wisconsin Madison

New research by University of Wisconsin-Madison scientists reveals how a cellular filament helps neural stem cells clear damaged and clumped proteins, an important step in eventually producing new neurons. The work provides a new cellular target for interventions that could boost neuron production when it’s needed most, such as after brain injuries. And because clumping proteins are a hallmark of many neurodegenerative diseases, like Alzheimer’s, the new study could provide insight into how these toxic proteins can be cleared away. Assistant Professor of Neuroscience Darcie Moore led the work with her graduate student Christopher Morrow. Their study is available online in the journal Cell Stem Cell.

Artificial neurons now talking to real neurons with hope of creating a hybrid brain network

In focal brain diseases, a patient’s neural network loses key connections, preventing the brain from functioning as it miraculously should. But what if there was a way to restore those connections? An EU funded study is seeking to do just that by getting real biological neurons to synaptically communicate with artificial ones.

Though still in the early stages of study, SYNCH, a team of scientists from the U.K., Switzerland, Germany, and Italy, have created what they describe as a “synaptically connected brain-silicon Neural Closed-loop Hybrid system.” Basically, they’ve taken actual brain cells and artificial brain cells, and got them talking back and forth over the internet.

Coronavirus Live Updates: Global Risk is ‘Very High,’ W.H.O. Says as Epidemic Spreads

Read updates in Chinese: 新冠病毒疫情最新消息汇总

Fears take hold that a global pandemic is inevitable.

From eastern Asia, Europe, the Middle East, the Americas and Africa, a steady stream of new cases on Friday fueled the sense that the new coronavirus epidemic may be turning into a global pandemic, with some health officials saying it may be inevitable.

Dog tests positive for coronavirus and quarantined in Hong Kong but experts say don’t panic as canines can’t carry bug

THE PET dog of a coronavirus patient in Hong Kong has tested positive for the deadly disease.

The owner of the dog, Yvonne Chow Hau Yee, who lives with her beloved Pomeranian, tested her pet pooch after being diagnosed with COVID-19.

The dog has been quarantined by officials, suggesting they have concerns that the pet could pass on the disease.

Should we edit our DNA? An imagined future of gene editing – video

There are decisions being made right now that could have an effect on global populations for generations to come. As part of this project, we commissioned an artist to investigate some of the themes raised in the podcasts. This work of fiction imagines a future where gene editing has become mainstream and discusses the moral, ethical and political divides that this might create.

Building a Positive Genetic Future for All

Nearly every day, new discoveries are pushing the genetics revolution ever-forward. It’s hard to imagine it’s been only a century and a half since Gregor Mendl experimented with his peas, six decades since Watson and Crick identified the double helix, fourteen years since the completion of the human genome project, and five years since scientists began using CRISPR-cas9 for precision gene editing. Today, these tools are being used in ways that will transform agriculture, animal breeding, healthcare, and ultimately human evolution.

Common practices like in vitro fertilization (IVF) and preimplantation embryo selection make human genetic enhancement possible today. But as we learn more and more about what the genome does, we will be able to make increasingly more informed decisions about which embryos to implant in IVF in the near term and how to manipulate pre-implanted embryos in the longer-term. In our world of exponential scientific advancement, the genetic future will arrive far faster than most people currently understand or are prepared for.

Human genetic science is one of the most important and potentially beneficial advancements of our time, but the monumental health and well-being benefits of these technologies could be overwhelmed by fear, hysteria, and international conflict if a foundation for informed and inclusive public and governmental dialogue is not laid as soon as possible.

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