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Researchers develop painless method to evaluate tumor progression

NANJING — Chinese researchers have developed a new evaluating model using medical imaging to help painlessly evaluate tumor progression in patients.

Doctors usually use the biological characteristics of tumors to observe the progress and response to treatment, such as if there are gene mutations or malignant features. Previous studies have shown that identifying the biological characteristics may contribute to better treatment and may increase survival rates.

Traditional methods to get tumor tissue include surgery and puncture, which are invasive, painful and costly.

Over 6,000 antibiotic resistance genes found in bacteria that inhabit the gut

Researchers have identified over 6,000 antibiotic resistance genes found in bacteria that inhabit the human gut, which is home to trillions of micro-organisms, mainly bacteria.

“Most gut bacteria live in a harmless relationship with the human host. However, the gut is also home to bacteria that can cause infections in hospitalised patients,” said one of the researchers Willem van Schaik, Professor at the University of Birmingham.

“Unfortunately, these bacteria are becoming increasingly resistant to antibiotics and we need to understand the processes that contribute to this development,” he added.

Precision genome engineering

Biotechnology
Genome editing through CRISPR-Cas systems has the potential to correct genetic mutations that occur in diseased cells, such as cancer cells. However, the ability to selectively activate CRISPR-Cas systems in diseased cells is important to ensure that gene editing only occurs where it is wanted. Zhu et al. developed a system whereby gene editing could be activated by a magnetic field, thus allowing spatial control. The use of nanomagnets in their system also improved transduction into target cells in tumor-bearing mouse models. This approach could potentially allow the translation of CRISPR-Cas systems into therapeutic agents.

Nat. Biomed. Eng. 10.1038/s41551-018‑0318-7 (2018).

Universal flu vaccine remains ‘an alchemist’s dream’

In theory, a universal flu vaccine would work if it contained parts of the virus that remained the same from year to year, the so-called conserved epitopes that make the pathogen less viable if they change. But no one has yet found the viral pieces capable of stimulating an immune response that stops most flu viruses afflicting humans.


A rapidly changing virus and a complex immune response stymie developers.

This ‘Cube’ Lets You Experience the Earth’s Most Extreme Conditions

From blizzards on top of Mount Everest to the extreme cold of the Arctic to the scorching heat of the Sahara deserts, researchers can now recreate the Earth’s most extreme climates and conditions — all in one place.

The research infrastructure, terraXcube, which opened to the public in Bolzano, South Tryol, Italy, on November 30, can simulate the world’s most extreme climate and weather conditions. It can recreate environmental factors such as air pressure, air humidity, and solar radiation individually or in combination, enabling researchers to investigate how the human body reacts to various extreme climatic conditions.

Ira Pastor — IdeaXme — Longevity Ambasador

Very excited to join IdeaXme (http://radioideaxme.com/) as Longevity Ambassador, utilizing this wonderful media platform to help expand global awareness of the people engineering a future free of aging, disease, degeneration, and suffering.

Using Artificial Intelligence to fix healthcare

Surgery filmed in 360° and live-streamed to remote doctors could already be happening in a hospital near you.

The healthcare industry should be using Artificial Intelligence (AI) to a far greater degree than at present, but progress has been painfully slow. The same factors that make the healthcare system so attractive to AI developers – fragmented or non-existent data repositories, outdated computer systems and doctor shortages – are the same things that have stopped AI from providing the gains that should be created.

The healthcare sector also presents unique obstacles for AI: data must flow freely through AI systems to achieve real results, but extracting data from handwritten patient files or PDFs is cumbersome for us, and difficult for AI. Despite technical and operational challenges, new research suggests that the arrival of the tech giants into the industry may provide the data and the capital required to digitize this fairly untapped market.