An exclusive interview with Ichor, the biotech company pioneering a SENS based repair therapy that could help cure age related blindness.
Check out our exclusive interview with Ichor the company taking the first SENS based therapy to the clinic. Should clinical trials be a success this will mark the arrival of a technology that addresses one of the aging processes.
Are 3D printed pills the future? We visited a London laboratory to find out.
Established by academics from University College London (UCL) in 2014, FabRx is a company seeking commercialize 3D printed medicines and devices. On the principle that everyone is different, the vision of 3D printed pills it to be able to provide more personal and specific care to patients in need.
Dr. Alvaro Goyanes is one of the four founding partners of FabRx and the company’s director of development. Dr. Goyanes invited 3D Printing Industry into the lab at UCL’s School of Pharmacy to find out more about the ongoing FabRx research.
Amazing Genes are HIDDEN inside of us; Science has found it. In 2014 one of the craziest science experiments by some incredible scientists at Oxford University found that less than 10% of human DNA is active, meaning that the majority of your genetic code is just sitting around doing nothing.
If you’ve ever been in a fight with a child, and I know I have, you’ll soon realise that their bodies have an uncanny ability to heal faster than an adult’s. Every human on Earth possesses a gene called ACTN3, but for some people this gene possesses a very special ability — the ability to be totally badass at sports. When my head is in a bouquet of flowers or I’m hovering over a batch of freshly baked cookies, I wonder how great this must smell to a dog. Remember that movie where Bruce Willis had unbreakable bones and Samuel L Jackson played a weird guy who said he was unbreakable and he proved it when he was in a car crash and his bones were unbreakable?The ability to hibernate for months at a time is a trait man has envied ever since the invention of the Lay-Z-Boy. Instead of sleeping for months, how awesome would it be to need no more than four hours sleep and still feel as refreshed as you would after sleeping in till noon? Remember the mice from the regeneration gene entry? Ever wanted to swim underwater without having to worry about that pesky little thing called drowning? On the surface this ability may sound pretty neat, because imagine how good chocolate or steak would be if your sense of taste was ramped up a few notches? The ability to become infected by an ancient virus may not seem like the best dormant trait to wake up, but they can’t all be winners now can they?
Tech to aid video search, detection of disease and of fraud.
Artificial intelligence has been the secret sauce for some of the biggest technology companies. But technology giant Alphabet Inc.’s Google is betting big on ‘democratising’ artificial intelligence and machine learning and making them available to everyone — users, developers and enterprises.
From detecting and managing deadly diseases, reducing accident risks to discovering financial fraud, Google said that it aimed to improve the quality of life by lowering entry barriers to using these technologies. These technologies would also add a lot of value to self-driving cars, Google Photos’ search capabilities and even Snapchat filters that convert the images of users into animated pictures.
Researchers have successfully used spinach leaves to build functioning human heart tissue, complete with veins that can transport blood.
To tackle a chronic shortage of donor organs, scientists have been working on growing various tissues and even whole organs in the lab. But culturing a bunch of cells is only part of the solution — they simply won’t thrive without a constant blood supply.
It’s notoriously difficult to build a working network of fine blood vessels (also called vasculature), especially when you get down to capillaries, which are only 5 to 10 micrometres wide. Blood vessels transport the oxygen and nutrients that a lab-grown tissue sample needs to grow and function.
To put it mildly, sequencing and building a genome from scratch isn’t cheap. It’s sometimes affordable for human genomes, but it’s often prohibitively expensive (hundreds of thousands of dollars) whenever you’re charting new territory — say, a specific person or an unfamiliar species. A chromosome can have hundreds of millions of genetic base pairs, after all. Scientists may have a way to make it affordable across the board, however. They’ve developed a new method, 3D genome assembly, that can sequence and build genomes from the ground up for less than $10,000.
Where earlier approaches saw researchers using computers to stick small pieces of genetic code together, the new technique takes advantages of folding maps (which show how a 6.5ft long genome can cram into a cell’s nucleus) to quickly build out a sequence. As you only need short reads of DNA to make this happen, the cost is much lower. You also don’t need to know much about your sample organism going in.
As an example of what’s possible, the team completely assembled the three chromosomes for the Aedes aegypti mosquito for the first time. More complex organisms would require more work, of course, but the dramatically lower cost makes that more practical than ever. Provided the approach finds widespread use, it could be incredibly valuable for both biology and medicine.
Although technology has long affected the labor force, recent advances in artificial intelligence and robotics are heightening concerns about automation replacing a growing number of occupations, including highly skilled or “knowledge-based” jobs.
Just a few examples: self-driving technology may eliminate the need for taxi, Uber and truck drivers, algorithms are playing a growing role in journalism, robots are informing consumers as mall greeters, and medicine is adapting robotic surgery and artificial intelligence to detect cancer and heart conditions.
More than 45 million couples worldwide grapple with infertility, but current standard methods for diagnosing male infertility can be expensive, labor-intensive, and require testing in a clinical setting.
Cultural and social stigma, and lack of access in resource-limited countries, may prevent men from seeking an evaluation. Investigators at Harvard-affiliated Brigham and Women’s Hospital (BWH) and Massachusetts General Hospital (MGH) set out to develop a home-based diagnostic test that could be used to measure semen quality with a smartphone-based device. New findings by the team indicating that the analyzer can identify abnormal semen samples based on sperm concentration and motility criteria with approximately 98 percent accuracy are published online in today’s Science Translational Medicine.
“We wanted to come up with a solution to make male infertility testing as simple and affordable as home pregnancy tests,” said Hadi Shafiee, a principal investigator in the Division of Engineering in Medicine and Renal Division of Medicine at BWH. “Men have to provide semen samples in these rooms at a hospital, a situation in which they often experience stress, embarrassment, pessimism, and disappointment. Current clinical tests are lab-based, time-consuming, and subjective. This test is low-cost, quantitative, highly accurate, and can analyze a video of an undiluted, unwashed semen sample in less than five seconds.”
Two Provo doctors are using Microsoft’s HoloLens with advanced medical imaging to create holograms of MRIs and X-rays, and they’re certain this will change the way surgeons operate.
Every minute in the United States, 30 people require a blood transfusion. That equates to a lot of blood, and the problem is that not enough people donate. This bottleneck has long been an issue for medicine, and so many have been trying to find a way to artificially create large volumes to meet this demand.
A team of researchers from the University of Bristol and NHS Blood and Transplant may have finally cracked it. They’ve made a major breakthrough in the process of mass producing red blood cells, in what could technically be an unlimited supply of the stuff. While they now have a biological way of achieving this, they now need the manufacturing technology on a large enough scale in order to mass produce it.
Scientists have been able to create artificial blood before, but these earlier methods have been incredibly inefficient. They worked by taking stem cells, and then directly inducing them to form red blood cells. By doing this, they could create maybe 50,000 cells in one go, far short of the trillions typically needed for a blood transfusion.