Lifeboat Foundation: Safeguarding Humanity
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Category: biotech/medical – Page 2,511

TRENTON, N.J. (AP) — U.S. regulators on Friday approved a fast-acting, super-potent opioid tablet that is 10 times more powerful than Fentanyl and 1,000 times more potent than morphine.

The drug called Dsuvia was developed as an alternative to IV painkillers used in hospitals.

The decision by the Food and Drug Administration came over objections from critics who fear the pill will be abused. In a lengthy statement, FDA Commissioner Scott Gottlieb said there will be “very tight restrictions” placed on its distribution and it is intended only for supervised settings like hospitals.

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Rutgers scientists have created a tiny, biodegradable scaffold to transplant stem cells and deliver drugs, which may help treat Alzheimer’s and Parkinson’s diseases, aging brain degeneration, spinal cord injuries and traumatic brain injuries.

Stem cell transplantation, which shows promise as a treatment for central nervous system diseases, has been hampered by low cell survival rates, incomplete differentiation of cells and limited growth of neural connections.

So, Rutgers scientists designed bio-scaffolds that mimic natural tissue and got good results in test tubes and mice, according to a study in Nature Communications. These nano-size scaffolds hold promise for advanced stem cell transplantation and neural tissue engineering. Stem cell therapy leads to stem cells becoming neurons and can restore neural circuits.

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“There was something else, too – something weirder. Of all the non-human DNA fragments the team gathered, 99 percent of them failed to match anything in existing genetic databases the researchers examined. We found a whole new class of human-infecting ones that are closer to the animal class than to the previously known human ones, so quite divergent on the evolutionary scale.”

A landmark Stanford 2017 study indicates that more than 99 percent of the microbes inside us are unknown to science. The survey of DNA fragments circulating in the blood suggests the microbes living within us are vastly more diverse than previously known. In fact, 99 percent of that DNA has never been seen before.

A new survey of DNA fragments circulating in human blood suggests our bodies contain vastly more diverse microbes than anyone previously understood. What’s more, the overwhelming majority of those microbes have never been seen before, let alone classified and named, Stanford researchers reported in the Proceedings of the National Academy of Sciences.

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The adjusted absolute reduction in mortality in expansion states versus non-expansion states was 0.6 percentage points. Since end-stage renal disease affects more than 100,000 Americans each year, 0.6 percentage points equals hundreds of deaths annually, Trivedi says.

Better access to care

More research is necessary to determine exactly what caused the decrease in deaths, but the study suggests expanded insurance coverage, which provided better access to care, was the key factor in reducing mortality among this group. Medicaid expansion reduced the rate of end-stage renal disease patients without insurance by 4.2 percentage points, primarily through Medicaid coverage.

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Active discussion on tne most effective technologies in comments to this page post. Number one is blood plasma-derived therapy.

Money has been pouring into startups researching longevity as treatments for aging become more of a reality. Here are the venture funds and pharma companies placing bets.

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A college student-athlete in Kansas died suddenly from a rare bacterial infection after thinking her symptoms were due to tonsillitis, according to news reports.

The 23-year-old, Samantha Scott, was a top coxswain on the rowing team at Kansas State University, according to a statement from the university. But about two weeks ago, she started to feel unwell.

Initially, it was thought that Scott had tonsillitis, or inflammation of the tonsils, according to local news outlet KDVR. Tonsillitis can cause symptoms such as sore throat, fever and pain when swallowing. But Scott had actually developed an illness called Lemierre syndrome, a condition that’s so rare it was referred to as “all-but-forgotten disease” in a 2006 report of a similar case. [27 Oddest Medical Cases].

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