Cancer will become easier to detect and diagnose early using magnetic resonance imaging (MRI) thanks to A*STAR researchers who have engineered biocompatible iron oxide nanoparticle contrast agents¹.
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Category: biotech/medical – Page 2,504
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About 15 years ago, UNC Lineberger’s Dale Ramsden, Ph.D., was looking through a textbook with one of his students when they stumbled upon a scientific mystery.
A small line in the book indicated that a protein that helps repair major breaks in our genetic code did so by adding DNA, or deoxyribonucleic acid, as expected. However, there were hints that it could also add RNA, or ribonucleic acid, at least in a test tube. It seemed unlikely that this would occur during repair of DNA in living cells, since RNA is normally used only as a messenger to carry information from the genetic code to make proteins.
“You would think they must only add DNA during repair of our genetic code, because that’s the core of the central dogma of life; genetic information has to be DNA all the time,” said Ramsden, who is a professor in the UNC School of Medicine Department of Biochemistry and Biophysics. “That’s the way it’s supposed to be. That’s what we’re taught in school.”
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It is predicted that artificial intelligence (AI) will transform many aspects of our life including healthcare and genomics. AI and machine learning have helped us to understand the genome of organisms and will potentially change the way we treat disease, determine effective drugs and edit genes.
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Chemical substances and nanomaterials are processed on a massive scale in diverse products, while their risks have not been properly assessed. Time and again synthesised substances have been shown to pollute the environment more than lab tests predicted. This is the warning given by Professor of Ecotoxicology Martina Vijver from Leiden University in her inaugural lecture on 16 November.
Laboratory tests are inadequate, according to Vijver, because they do not imitate a complete ecosystem. In her inaugural lecture she will discuss in greater detail two examples of substances where more realistic research is needed: agricultural toxins and nanoparticles. ‘But the same can be said for many other groups of substances, such as antibiotics, plasticizers and GenX.’
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