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(CNN) — Intensive lowering of blood pressure, to a less than 120 mm Hg level, can have a measurable impact on mild cognitive impairment (MCI) — a well-established precursor of dementia, a new study finds.

Previous studies have suggested high blood pressure could be a risk factor for dementia and mild cognitive impairment, leading US researchers to explore whether lowering pressure could reduce this risk in a large randomized trial on more than 9000 people.

Lowering blood pressure did not significantly reduce dementia risk, but the secondary results showed a significant reduction in MCI, according to the study published Monday.

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For a long time, biohackers have been playing with magnets by embedding then under their skin as a novelty extra-sensation. I, personally, don’t see the point, but morphological, taxonomic, and cladic freedom are at work so I celebrate their actions.


Our skin’s ability to perceive pressure, heat, cold, and vibration is a critical safety function that most people take for granted. But burn victims, those with prosthetic limbs, and others who have lost skin sensitivity for one reason or another, can’t take it for granted, and often injure themselves unintentionally.

Chemists Islam Mosa from UConn, and James Rusling from UConn and UConn Health, along with University of Toronto engineer Abdelsalam Ahmed, wanted to create a sensor that can mimic the sensing properties of skin. Such a sensor would need to be able to detect pressure, temperature, and vibration. But perhaps it could do other things too, the researchers thought.

“It would be very cool if it had abilities human skin does not; for example, the ability to detect magnetic fields, sound waves, and abnormal behaviors,” said Mosa.

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The gut microbiome is made up of billions of bacteria, and scientists have been trying to understand exactly how they affect our health, contribute to our risk of contacting diseases and how they interact with the vital organs and systems in the body, including the brain. It is quite a lot to unpick.


As countries industrialise, their air becomes dirtier – and this could have some far-reaching effects on the beneficial bacteria inside us.

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This is not hyperbole. AMR already leads to at least 700,000 deaths every year. But the impact goes further — resistant genes in people and animals cross ecological, species and geographical borders. Progress against diseases including HIV, malaria and tuberculosis is threatened globally. In 2016, the World Health Organization reported that nearly half a million people developed drug-resistant tuberculosis. Even cancer patients are more at risk as most treatments suppress the immune system and would, along with several routine surgical operations, become too risky without effective antibiotics.


The world urgently needs a new financing model for antibiotics.

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A small team of Israeli scientists think they might have found the first complete cure for cancer.

“We believe we will offer in a year’s time a complete cure for cancer,” said Dan Aridor, of a new treatment being developed by his company, Accelerated Evolution Biotechnologies Ltd. (AEBi), which was founded in 2000 in the ITEK incubator in the Weizmann Science Park. AEBi developed the SoAP platform, which provides functional leads to very difficult targets. “Our cancer cure will be effective from day one, will last a duration of a few weeks and will have no or minimal side-effects at a much lower cost than most other treatments on the market,” Aridor said. “Our solution will be both generic and personal.”

It sounds fantastical, especially considering that an estimated 18.1 million new cancer cases are diagnosed worldwide each year, according to reports by the International Agency for Research on Cancer. Further, every sixth death in the world is due to cancer, making it the second leading cause of death (second only to cardiovascular disease).

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Attitudes about life extension have significantly changed within the last decade.


While medical schools have had the idea that aging should be brought under medical control for over a century, the explicit desire to greatly extend one’s life remained rare – until very recently. A new study by YouGov, a market intelligence company that researches multiple topics, found that, today, one in five Americans agrees with the statement “I want to live forever.” Is this the result of some sort of bias, or does it mean that we are reaching a turning point, after which society will start boldly and unambiguously clamoring for the cure for aging?

The desire for a long life

The wish to remain healthy and young and live significantly longer has accompanied humanity since its dawn. The most ancient myths and the very first pieces of literature, such as the Epic of Gilgamesh, tried to explain human aging and mortality, and they pictured heroes who pursued ways to live indefinitely or to save their loved ones. These early motivations are woven into modern religions, and they eventually caused life and health to be considered universal human rights that have to be valued and protected.

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#OpenAccess #FullArticle The results of a new clinical trial have shown the safety and efficacy of the interoperable Artificial Pancreas System smartphone app (iAPS), which can interface wirelessly with leading continuous glucose monitors (CGM), insulin pump devices, and decision-making algorithms. The clinical trial and the app, which runs on an unlocked smartphone, are described in an article published in Diabetes Technology & Therapeutics (DTT), a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.


Diabetes Technology & TherapeuticsVol. 21, No. 1Original ArticlesFree AccessSunil Deshpande,…

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