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Researchers at the University of Texas at Arlington have recently explored the use of machine learning for emotion recognition based solely on paralinguistic information. Paralinguistics are aspects of spoken communication that do not involve words, such as pitch, volume, intonation, etc.

Recent advances in have led to the development of tools that can recognize by analyzing images, voice recordings, electroencephalograms or electrocardiograms. These tools could have several interesting applications, for instance, enabling more efficient human-computer interactions in which a computer recognizes and responds to a human user’s emotions.

“In general, one may argue that speech carries two distinct types of : explicit or linguistic information, which concerns articulated patterns by the speaker; and implicit or paralinguistic information, which concerns the variation in pronunciation of the linguistic patterns,” the researchers wrote in their paper, published in the Advances in Experimental Medicine and Biology book series. “Using either or both types of information, one may attempt to classify an audio segment that consists of speech, based on the emotion(s) it carries. However, from speech appears to be a significantly difficult task even for a human, no matter if he/she is an expert in this field (e.g. a psychologist).”

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How would you like to take one injection that has multiple genes that improve cellular repair and regeneration, keeping your cells younger and healthier longer? Today, BioViva and Rutgers University are embarking on an ambitious research project to do just that; we are tackling humanities greatest foe — suffering and death due to aging.

Read the press release here:

https://www.eurekalert.org/pub_releases/2018-12/bui-rua121018.php

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Today, we present an interview with Reason, the editor of Fight Aging! and co-founder of Repair Biotechnologies. We asked him about the state of rejuvenative therapies, some of which may be available in the near future.

Fight Aging! was the first blog that tackled the science of aging in a serious fashion. Many people still treat it as the go-to site for high-quality information and opinion on the rapidly growing field of biogerontology.

Reason (he goes by only his first name), the brain behind the Fight Aging! blog, has been involved in one way or another with anti-aging science for almost two decades as a writer, researcher, and investor. His new company, Repair Biotechnologies, is focused mainly on halting thymic atrophy and atherosclerosis, which causes about 20 percent of all human deaths.

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“Manuel has been a world-leading researcher in cell senescence for decades, and participated in various of our conferences starting many years ago. His latest breakthrough, which he will discuss in Berlin, is one of those head-slappingly brilliant concepts that I encounter at most once per year, combining a couple of long-established ideas in a completely novel way that potentially delivers far more than the sum of the parts. I won’t spoil the surprise here!” says Aubrey de Grey.

https://www.undoing-aging.org/news/dr-manuel-serrano-to-spea…aging-2019

#undoingaging #sens #foreverhealthy

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The tree of life just got another major branch. Researchers recently found a certain rare and mysterious microbe called a hemimastigote in a clump of Nova Scotian soil. Their subsequent analysis of its DNA revealed that it was neither animal, plant, fungus nor any recognized type of protozoan — that it in fact fell far outside any of the known large categories for classifying complex forms of life (eukaryotes). Instead, this flagella-waving oddball stands as the first member of its own “supra-kingdom” group, which probably peeled away from the other big branches of life at least a billion years ago.

“It’s the sort of result you hope to see once in a career,” said Alastair Simpson, a microbiologist at Dalhousie University who led the study.

Impressive as this finding about hemimastigotes is on its own, what matters more is that it’s just the latest (and most profound) of a quietly and steadily growing number of major taxonomic additions. Researchers keep uncovering not just new species or classes but entirely new kingdoms of life — raising questions about how they have stayed hidden for so long and how close we are to finding them all.

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Investigators from the Neurodegenerative Diseases Research Group at the University of Extremadura are studying signaling mediated by a pathway known as planar cell polarity (PCP), which regulates the coordinated orientation of cells during organogenesis, the process of organ formation in living organisms. This pathway has been highly conserved on the evolutionary scale, and one of its key functions in vertebrates is the regulation of the coordinated positioning of centrioles/ciliary basal cells inside cells.

This signaling pathway was discovered initially in the fruit fly genus Drosophila, although the majority of the pathway components have been retained in humans. It has likewise been observed that certain pathologies such as hydrocephaly, infertility and some kinds of cancers are associated with defective functioning of this signaling.

Under the auspices of the project EPICENTR within the Spanish national research plan, whose objective is to study the planar polarisation of centrioles in epithelial , the UEx researchers have now published the first results of their investigation in the journal Development. These results are related to the polarised positioning mechanism of centrioles in Drosophila and its correlation with actin.

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Mild cognitive impairment (MCI) is an intermediate stage between the expected cognitive decline of normal aging and the more-serious decline of dementia. It can involve problems with memory, language, thinking, and judgment that are greater than normal age-related changes.

If you have mild cognitive impairment, you may be aware that your memory or mental function has “slipped.” Your family and close friends also may notice a change. But generally these changes aren’t severe enough to significantly interfere with your day-to-day life and usual activities.

Mild cognitive impairment may increase your risk of later progressing to dementia, caused by Alzheimer’s disease or other neurological conditions. But some people with mild cognitive impairment never get worse, and a few eventually get better.

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Mammalian embryos are unlike those of any other organism as they must grow within the mother’s body. While other animal embryos grow outside the mother, their embryonic cells can get right to work accepting assignments, such as head, tail or vital organ. By contrast, mammalian embryos must first choose between forming the placenta or creating the baby.

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Medical research has taken a leap into the future as Russian scientists have managed to grow a mouse’s thyroid in zero gravity using a 3D bioprinter on the International Space Station (ISS). And human organs may be next in line.

The breakthrough device dubbed Organaut was delivered to the ISS by a Soyuz MS-11 spacecraft on December 3 by Expedition 58.

In what is no longer a plot of a sci-fi movie, the innovative device created a mouse’s thyroid in zero gravity. And the result was a success. Invitro, whose subsidiary 3D Bioprinting Solutions built the printer, told Ria Novosti: “We received photos from space. The camera clearly shows a living construction of a mouse’s thyroid being assembled.”

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