Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: biotech/medical – Page 2,206

Individuals of the same age may not age at the same rate. Quantitative biomarkers of aging are valuable tools to measure physiological age, assess the extent of ‘healthy aging’, and potentially predict health span and life span for an individual. Given the complex nature of the aging process, the biomarkers of aging are multilayered and multifaceted. Here, we review the phenotypic and molecular biomarkers of aging. Identifying and using biomarkers of aging to improve human health, prevent age-associated diseases, and extend healthy life span are now facilitated by the fast-growing capacity of multilevel cross-sectional and longitudinal data acquisition, storage, and analysis, particularly for data related to general human populations. Combined with artificial intelligence and machine learning techniques, reliable panels of biomarkers of aging will have tremendous potential to improve human health in aging societies.

Keywords: physiological age, phenotypic, molecular, age-associated diseases, aging process.

Aging is the time-dependent physiological functional decline that affects most living organisms, which is underpinned by alterations within molecular pathways, and is also the most profound risk factor for many non-communicable diseases. To identify biomarkers of aging would, on one hand, facilitate differentiation of people who are of the same chronological age yet have variant aging rates. Quantitative biomarkers of aging could also define a panel of measurements for ‘healthy aging’ and, even further, predict life span. On the other hand, biomarkers of aging could also assist researchers to narrow their research scope to a specific biological facet in their attempts to explain the biological process behind aging or aging-related diseases. Here, we review the phenotypic and molecular biomarkers of aging. Phenotypic biomarkers can be non-invasive, panoramic, and easy to obtain, whereas molecular biomarkers can reflect some of the molecular mechanisms underlying age status.

Read more | >

A message to our readers: Have you checked out our NEW on demand video platform called CETV? We created it to combat censorship and support the important journalism we are doing. Visit CETV.one to sign up for a free 7 day trial here. Thank you for your support!

Recently, an 82-year-old woman who suffered from dementia, who couldn’t recognize her own son has miraculously got her memory back after changing her diet.

When his mother’s condition became so severe that for her own safety she had to be kept in the hospital, Mark Hatzer almost came to terms with losing another parent.

Read more | >

Researchers have developed a new treatment method capable of detecting Lyme disease in just 15 minutes.

Caused by Borrelia burgdorferi and transmitted by the bite of infected Ixodes ticks, Lyme disease if left untreated can cause serious neurologic, cardiac, and/or rheumatologic complications.

“Our findings are the first to demonstrate that Lyme disease diagnosis can be carried out in a microfluidic format that can provide rapid quantitative results,” said Sam Sia, professor of biomedical engineering at Columbia Engineering.

Read more | >

Unfortunately, as we age they begin to breakdown due to damage.

MitoSENS project aims to reverse that damage with the goal of preventing age-related ill health. In their first study, they managed to show that allotopic expression of two mtDNA genes from the nucleus could bring back several functions in a patient cell line.

MitoSENS team is currently running a crowdfunding campaign on Lifespan.io to collect money for the next crucial step of this project. Scientists want to investigate if functional backup copies of mitochondrial DNA genes in the nucleus can replace their mutated counterparts in live animals, and if this could rescue mitochondrial function.

Read more | >

This year I had the privilege to record in full Liz Parrish talk delivered at RAADfest 2019 (Revolution Against Aging and Death Festival 2019), which took place in Las Vegas, NV from 3 to 6 of October.

During her talk, Liz tells us about recent developments in the field of gene therapy and what her company BioViva is doing to benefit society by harnessing the power of it.

Don’t miss it!!!

https://bioviva-science.com/

Home

Read more | >

NASA says the first humans will set foot on Mars in the mid-2030’s. It will be the most dangerous mission any human has ever taken. Glad You Asked host Cleo Abram wants to know: What comes after that? Not how do we get there, but how will we survive once we do?
Note: There are several Fahrenheit measurements in this piece.
The metric conversions are:
At 7:53: 212 degrees Fahrenheit = 100 degrees Celsius
At 8:04: 98.6 degrees Fahrenheit = 37 degrees Celsius
At 8:45: −81 degrees Fahrenheit = −62.8 degrees Celsius

You choose — watch all episodes uninterrupted with YouTube Premium now, or wait to watch new episodes free with ads.

Key sources:
International Space Station Integrated Medical Group Medical Checklist https://www.nasa.gov/centers/johnson/pdf/163533main_ISS_Med_CL.pdf

Examining Psychosocial Well-Being and Performance in Isolated, Confined, and Extreme Environments https://ston.jsc.nasa.gov/collections/TRS/_techrep/TM-2015-218565.pdf

Mars Exploration Program, NASA https://mars.nasa.gov/all-about-mars/facts/

NASA Johnson Space Center Oral History Project https://historycollection.jsc.nasa.gov/JSCHistoryPortal/hist…#45;01.htm

Continue reading “Will We Survive Mars? — Glad You Asked S1 (E1)” | >

On the surface, Ebola and the flu might not seem all that similar — one can cause organ failure or death, while the other usually just makes you feel really crummy — but they actually have the same underlying cause: an RNA-based virus.

That’s the type of virus behind some of the most common — and deadly — illnesses in the world, and researchers have just discovered a way to use the powerful gene-editing technology CRISPR in the fight against them.

On Thursday, a team lead by researchers from Harvard and MIT’s Broad Institute published a study in the journal Molecular Cell detailing their creation of CARVER (Cas13-Assisted Restriction of Viral Expression and Readout), a system that utilizes the CRISPR enzyme Cas13, which “naturally targets viral RNA in bacteria,” according to a Broad Institute press release.

Read more | >

President Nana Addo Dankwa Akufo-Addo on Thursday opened Ghana’s newest medical drone delivery base at Asante Mampong as part of his duty tour of the Ashanti region this week.

This marks the second of what will be four medical drone delivery bases that have been commissioned to help expand access to critical and life-saving medicines for people across Ghana.

Zipline, a California-based robotics company, operates the medical drone delivery service with support from Gavi, the Vaccine Alliance, the Bill & Melinda Gates Foundation, the UPS Foundation and other partners.

Read more | >

Researchers at EPFL have created a metallic microdevice in which they can define and tune patterns of superconductivity. Their discovery, which holds great promise for quantum technologies of the future, has just been published in Science.

In superconductors, electrons travel with no resistance. This phenomenon currently only occurs at very low temperatures. There are many , such as magnetic resonance imaging (MRI). Future technologies, however, will harness the total synchrony of electronic behavior in superconductors—a property called the phase. There is currently a race to build the world’s first quantum computer, which will use phases to perform calculations. Conventional superconductors are very robust and hard to influence, and the challenge is to find in which the can be easily manipulated in a device.

EPFL’s Laboratory of Quantum Materials (QMAT), headed by Philip Moll, has been working on a specific group of unconventional superconductors known as heavy fermion materials. The QMAT scientists, as part of a broad international collaboration between EPFL, the Max Planck Institute for Chemical Physics of Solids, the Los Alamos National Laboratory and Cornell University, made a surprising discovery about one of these materials, CeIrIn5.

Read more | >