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Osteoarthritis reversed in rats with experimental drug combo

Osteoarthritis is one of the most common ailments of an aging population, but there aren’t many treatment options besides taking pain killers or getting a full joint replacement. Now, researchers at the Salk Institute have found that a combination of two experimental drugs appears to reverse the symptoms of the disorder, with successful tests conducted in rats and in human cells in the lab.

As we age, our bodies gradually lose the ability to repair damage as fast as it needs to. That means that tissues subjected to high-intensity long-term use, such as cartilage in joints, are especially prone to wearing out. That manifests itself in the common condition of osteoarthritis, resulting in pain when that joint moves.

In the past, two molecules have been identified as having decent potential for treating the disease – alpha-KLOTHO (αKLOTHO) and TGF beta receptor 2 (TGFβR2). Previous tests only showed moderate success, so the researchers on the new study decided to see if they fared any better when used together.

Fit to burst: How cancer-exploding viruses are changing the game

Very interesting, researches probably already know.


You awake in the middle of the night from a nightmare.

In the nightmare, you are standing in a room that is completely full, floor to ceiling, of balloons. There are red ones, purple ones, yellow ones and green ones.

You’ve been told to burst only the green and purple balloons. Bursting the red or yellow ones will have disastrous consequences.

Ms. Suzanne Somers — Actress, Author, Singer, Businesswoman, Anti-Aging Advocate — Helping to spread the word about healthy longevity and emerging anti-aging technologies to millions — ideaXme — Ira Pastor

Chemistry in Coronavirus Research: A Free to Read Collection from the American Chemical Society

ACS Publications is providing free access to articles related to the #coronavirus, in support of the on-going coronavirus outbreak relief efforts in #China.

View the Virtual Issue to access all available articles:


In light of the current outbreak of a novel coronavirus (2019–nCoV), ACS Publications would like to share this Virtual Issue that features a collection of articles on coronavirus research. Chemistry has a key role to play in understanding everything from viral structure to pathogenesis, isolation of vaccines and therapies, as well as in the development of materials and techniques used by basic researchers, virologists and clinicians. This Virtual Issue aims to provide a brief overview of the important contributions of chemistry to understanding and controlling the spread of coronaviruses and includes articles from„„, and as well as the preprint server ChemRxiv. We hope the research contained in this Virtual Issue will provide you with important insight into challenges and approaches in virus research.

Handheld bioprinter for treating burns at the point-of-care

A burn that is over 25% of the human body area can be life threatening. However a burn that is only 1 percent but on a visible area of the body can be life-worsening. That is why advancements in the area of wound care and burns treatment are so important from patient perspective. Being a doctor of the future will include having a point-of-care device such as a 3D-Bioprinter that will scan the lesions in dept and width and print a gel imbued with cells and prolo-factors.

Forgive me my conservatism… we already have such clinics that are on the clinical trials for such treatments.

Read more in the article. Stay tuned for more topics through the Academy blog. Gain more knowledge in Regenerative Medicine and practical experience with biologics through the Annual Congress — Global Regenerative Congress 18–20 September 2020 in Dubai. Registrations are open: www.grc2020dubai.com


Researchers from the University of Toronto (ON, Canada) have reported success in trials of a handheld bioprinter for treating serious burns and wounds.

Handheld Skin 3D Printer Can Help Burn Victims

This handheld 3D printer deposits layers of skin tissue, and could one day help to heal deep wounds. Instead of waiting for skin patches to grow in a Petri dish, you apply it directly.

A team of Canadian scientists has successfully applied skin tissue to burn wounds using a handheld 3D printer. This technology may become a game-changer in the way severe burn victims are treated.

The handheld skin 3D printer, the work of scientists at the University of Toronto Engineering and Sunnybrook Hospital, was first shown back in 2018. Since then it has undergone a major redesign that improves upon the initial model’s functionality.

New Details About The Infamous ‘CRISPR Babies’ Experiment Have Just Been Revealed

More than a year ago, the world was shocked by Chinese biophysicist He Jiankui’s attempt to use CRISPR technology to modify human embryos and make them resistant to HIV, which led to the birth of twins Lulu and Nana.

Now, crucial details have been revealed in a recent release of excerpts from the study, which have triggered a series of concerns about how Lulu and Nana’s genome was modified.