Lifeboat Foundation

In Nature Neuroscience, researchers present a new method to grow a cerebral organoid from human stem cells that exhibits axon outgrowth with specific tract-like patterns. Read the paper here: https://go.nature.com/2HMQxtF

This new method could open a major avenue towards the full regeneration of body parts.

A new study has revealed a method of switching the early growth response of DNA on and off, opening the future possibility of regenerating human body parts with the use of genetic editing.

Continue reading “Researchers Discover DNA Switch for Full Body Regeneration” »

“We have long known that oxidative stress and inflammation are involved in making arteries unhealthy over time, but we didn’t know why arteries begin to get inflamed and stressed. Something is triggering this,” Seals said. “We now suspect that, with age, the gut microbiota begins producing toxic molecules, including TMAO, which get into the blood stream, cause inflammation and oxidative stress and damage tissue.”

As our collection of resident gut bacteria changes with age, it increasingly produces harmful metabolites that damage veins and blood vessels, driving disease, a new study suggests.

The Onion is well known for biting satire. This is NOT The Onion.

Massimiliano Fedriga, a member of Italy’s far-right League party, is dead-set against the country’s mandatory vaccination laws. Guess who contracted chickenpox and had to spend four days in the hospital?

Last year, resTORbio announced the positive results of its phase 2b human trial, which targeted the aging immune system with an immune system-boosting drug. Now, the company has announced the news that its therapy is moving to a phase 3 study later this year after successful negotiation with the FDA.

Targeting the mTOR pathway of aging

ResTORbio is a biopharmaceutical company that is developing therapies that directly target the aging processes in order to prevent or cure age-related diseases. Its primary candidate drug is RTB101, which targets part of the mTOR pathway, one of the pathways involved in aging.

A new study shows clear differences in the biology of how men and women feel pain, a reminder that sex-specific pain medications might benefit us all.

The link between heart disease and depression could be inflammation, research suggests.

The two conditions have been heavily linked to each other for years but scientists have struggled to explain why this is.

Now experts have found inflammation — the body’s first line of defence — could be to blame.

Continue reading “Heart disease and depression are linked” »

A common calcium-channel blocking heart medication has been tentatively linked to increased risk of sudden cardiac arrest. The research comes from the European Sudden Cardiac Arrest network (ESCAPE-NET), though additional work is needed to determine whether the findings can be replicated. At the heart of the study were medications amlodipine and nifedipine, which are prescribed for high blood pressure and chest pain called angina.