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Cornell researchers have made a new discovery about how seemingly minor aspects of the internal structure of bone can be strengthened to withstand repeated wear and tear, a finding that could help treat patients suffering from osteoporosis. It could also lead to the creation of more durable, lightweight materials for the aerospace industry.

The team’s paper, “Bone-Inspired Microarchitectures Achieve Enhanced Fatigue Life,” was published Nov. 18 in the Proceedings of the National Academy of Sciences. Co-authors include Cornell doctoral students Cameron Aubin and Marysol Luna; postdoctoral researcher Floor Lambers; Pablo Zavattieri and Adwait Trikanad at Purdue University; and Clare Rimnac at Case Western Reserve University.

For decades, scientists studying osteoporosis have used X-ray imaging to analyze the structure of bones and pinpoint strong and weak spots. Density is the main factor that is usually linked to strength, and in assessing that strength, most researchers look at how much load a bone can handle all at once.

Researchers at Northeastern have discovered a new antibiotic that could treat infections caused by some of the nastiest superbugs humanity is facing in the antibiotic resistance crisis.

But in the last few years, AI has changed the game. Deep-learning algorithms excel at quickly finding patterns in reams of data, which has sped up key processes in scientific discovery. Now, along with these software improvements, a hardware revolution is also on the horizon.

Yesterday Argonne announced that it has begun to test a new computer from the startup Cerebras that promises to accelerate the training of deep-learning algorithms by orders of magnitude. The computer, which houses the world’s largest chip, is part of a new generation of specialized AI hardware that is only now being put to use.

“We’re interested in accelerating the AI applications that we have for scientific problems,” says Rick Stevens, Argonne’s associate lab director for computing, environment, and life sciences. “We have huge amounts of data and big models, and we’re interested in pushing their performance.”

The brain cortex, the outside layer of our brain often referred to as grey matter, is one of the most complex structures found in living organisms. It gives us the advanced cognitive abilities that distinguish us from other animals.

Neuroscientist Professor Pierre Vanderhaeghen (VIB-KU Leuven, Université libre de Bruxelles) explains what makes the human brain so unique: “One remarkable feature of human neurons is their unusually long development. Neural circuits take years to reach full maturity in humans, but only a few weeks in mice or some months in monkeys.”

“This long period of maturation allows much more time for the modulation of brain cells and circuits, which allows us to learn efficiently for an extended period up until late adolescence. It’s a very important and unique feature for our species, but what lies at its origin remains a mystery.”