Lifeboat Foundation

A British woman has become the first person in the world to undergo gene therapy for the most common cause of sight loss.

Surgeons at the John Radcliffe Hospital in Oxford inserted a synthetic gene into the left eye of Janet Osborne, 80, who suffers from age-related macular degeneration (AMD).

Around 600,000 people in the UK are affected by AMD, which affects the central part of a patient’s vision with gaps or ‘smudges’, making everyday activities like reading and recognising faces difficult.

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Circa 2018

From medical to agricultural to solar, quantum dots have uses far beyond the humble TV.

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Summary: Researchers have identified a previously unknown form of neural communication. They report the findings could help better the understanding of neural activity associated with specific brain processing and neurological disorders.

Source: Case Western Reserve University.

Biomedical engineering researchers at Case Western Reserve University say they have identified a previously unidentified form of neural communication, a discovery that could help scientists better understand neural activity surrounding specific brain processes and brain disorders.

Liz talking about Rutgers, Integrated Health Systems, anti-aging vaccine(couple of years of gathering data), $75,000 single organ treatment, and potential for very affordable whole body treatment. Q&A at 32 minutes.

Liz Parrish | BioViva, presents at People Unlimited’s Ageless Education, about Gene Therapy Advancements.

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Scientists said Monday they had discovered immune cells that can fight all known flu viruses in what was hailed as an “extraordinary breakthrough” that could lead to a universal, one-shot vaccine against the killer disease.

Influenza epidemics, largely seasonal, kill hundreds of thousands of people each year, according to the World Health Organization.

Due to its mutating strains, vaccine formulas must be regularly updated and only offer limited protection currently.

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UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally “invisible” to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants. Because these “universal” stem cells can be manufactured more efficiently than stem cells tailor-made for each patient—the individualized approach that dominated earlier efforts—they bring the promise of regenerative medicine a step closer to reality.

“Scientists often tout the therapeutic potential of pluripotent stem cells, which can mature into any adult tissue, but the immune system has been a major impediment to safe and effective stem cell therapies,” said Tobias Deuse, MD, the Julien I.E. Hoffman, MD, Endowed Chair in Cardiac Surgery at UCSF and lead author of the new study, published Feb. 18 in the journal Nature Biotechnology.

The immune system is unforgiving. It’s programmed to eradicate anything it perceives as alien, which protects the body against infectious agents and other invaders that could wreak havoc if given free rein. But this also means that transplanted organs, tissues or cells are seen as a potentially dangerous foreign incursion, which invariably provokes a vigorous immune response leading to transplant rejection. When this occurs, donor and recipient are said to be—in medical parlance—” histocompatibility mismatched.”

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Circa 2015

The first successful vaccination of deer against chronic wasting disease is reported in the journal Vaccine, (Vaccine 2015;38:726–33), posted online in advance of print Dec. 21, 2014.

Researchers say the breakthrough may not only protect U.S. livestock against CWD but may also shed new light on human diseases suspected of being caused by prion infections, such as Creutzfeldt-Jakob disease, kuru, familial insomnia, and variably protease-sensitive prionopathy. Some studies also have associated prionlike infections with Alzheimer’s disease.

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Another medical miracle from Israel…

Our morning routine could be appended to something like “breakfast, stretching, sit on a medical examiner, shower, then commute.” If we are speaking seriously, we don’t always get to our morning stretches, but a quick medical exam could be on the morning agenda. We would wager that a portion of our readers are poised for that exam as they read this article. The examiner could come in the form of a toilet seat. This IoT throne is the next device you didn’t know you needed because it can take measurements to detect signs of heart failure every time you take a load off.

Tracking heart failure is not just one test, it is a buttload of tests. Continuous monitoring is difficult although tools exist for each test. It is unreasonable to expect all the at-risk people to sit at a blood pressure machine, inside a ballistocardiograph, with an oximeter on their fingers three times per day. Getting people to browse Hackaday on their phones after lunch is less of a struggle. When the robots overthrow us, this will definitely be held against us.

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