Lifeboat Foundation

A new study reported that SARS-CoV-2, the virus that causes COVID, can infect dopamine neurons in the brain and trigger senescence—when a cell loses the ability to grow and divide. The researchers from Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center, and Columbia University Vagelos College of Physicians and Surgeons suggest that further research on this finding may shed light on the neurological symptoms associated with long COVID, such as brain fog, lethargy, and depression.

The findings, published in Cell Stem Cell on Jan. 17, show that dopamine neurons infected with SARS-CoV-2 stop working and send out chemical signals that cause inflammation. Normally, these neurons produce dopamine, a neurotransmitter that plays a role in feelings of pleasure, motivation, memory, sleep, and movement. Damage to these neurons is also connected to Parkinson’s disease.

“This project started out to investigate how various types of cells in different organs respond to SARS-CoV-2 infection. We tested lung cells, heart cells, pancreatic beta cells, but the senescence pathway is only activated in dopamine neurons,” said senior author Dr. Shuibing Chen, director of the Center for Genomic Health, the Kilts Family Professor Surgery and a member of the Hartman Institute for Therapeutic Organ Regeneration at Weill Cornell Medicine. “This was a completely unexpected result.”

MKUltra is not referenced explicitly on Stranger Things — the popular Netflix show — but the series seems to be inspired by the controversial CIA program. In the show, a government laboratory is conducting illegal experiments on a young girl and other persons, torturing them, and harnessing their special abilities for their own purposes. This is similar to the goals of the CIA human experimentation project, which was started 70 years ago.

Controversial and unethical experiments were conducted on human subjects by the Agency for the MKUltra project, including the use of mind control techniques and the administration of drugs such as LSD and other chemicals. Electroshock, hypnosis, sensory deprivation, verbal and sexual abuse, and other forms of torture were also part of the non-consensual experiments, which were created because the CIA was convinced that communists had discovered a way to control human minds. Its activities — which were hidden and classified before their files being destroyed after an investigation — remain a subject of concern and investigation to this day.

MKUltra was a CIA program involving the research and development of chemical and biological agents. According to official documents, it was “concerned with the research and development of chemical, biological and radiological materials capable of employment in clandestine operations to control human behavior.”

“The protein prevents the cancer cells from becoming more aggressive and spreading,” researcher Abhimanu Pandey said.

People below the age of 50 are getting cancer more than ever before — and doctors are stumped as to why.

As the Wall Street Journal reports, the shocking 2020 death of beloved actor Chadwick Boseman, who died of colorectal cancer at only 43 years old, seemed to wake the public up to the growing trend that researchers had been warning about for a decade prior.

“Colorectal cancer was the canary in the coal mine,” mused cancer epidemiologist Timothy Rebbeck of the Dana-Farber Cancer Institute in Boston. Soon after, there was seemingly an explosion of all different types of cancers, many of which deal with or are near the gastrointestinal tract: appendix, pancreatic, stomach, and uterine.

CTWAS is a novel tool designed to spot genes that make us sick.

This novel tool applies advanced statistics to study complex data from the human genome and pinpoints the genes that cause illnesses.

The findings revealed that out of six children subjected to the gene therapy, five exhibited restored hearing and enhanced speech recognition.

Furthermore, the remaining incidents were ephemeral and had no lasting impact, showing that the detected adverse effects were just short and did not raise long-term issues.

“We are the first to initiate the clinical trial of OTOF gene therapy. It is thrilling that our team translated the work from basic research in animal model of DFNB9 to hearing restoration in children with DFNB9,” said Yilai Shu, lead study author from the Eye & ENT Hospital of Fudan University, in a press release.

Continue reading “Joint US-China gene therapy trials restore hearing in 5 kids, a first” »

This could possibly contribute towards saving lives.

Researchers have developed and tested an innovative machine-learning approach that could one day enable the earlier detection of cancer in patients by using smaller blood draws.

FDA approved the device by DermaSensor last week.

In a recent pioneering development, the US Food and Drug Administration (FDA) granted marketing authorization to the DermaSensor, an artificial intelligence-powered hand-held device designed for the early detection of skin cancers such as melanoma, basal cell carcinoma, and squamous cell carcinoma.

Predominantly tailored for use by primary care physicians, DermaSensor uses elastic scattering spectroscopy to look at cellular and subcellular characteristics of suspicious skin lesions.

Continue reading “US FDA approves world’s first AI-powered skin cancer detecting device” »

Soft robots, medical devices, and wearable devices are now common in our daily routines. Researchers at KAIST have created a fluid switch that employs ionic polymer artificial muscles. This switch functions with ultra-low power while generating a force 34 times its own weight. Fluid switches are designed to direct the flow of fluid, guiding it in specific directions to initiate different movements.

KAIST (President Kwang-Hyung Lee) announced on the 4th of January that a research team under Professor IlKwon Oh from the Department of Mechanical Engineering has developed a soft fluidic switch that operates at ultra-low voltage and can be used in narrow spaces.