The Biden administration is expected to announce this week it is purchasing 10 million courses of treatment Pfizer’s covid pill, a multibillion dollar investment in a medication that officials hope will help change the trajectory of the pandemic by staving off many hospitalizations and deaths, according to two people with knowledge of the transaction.
-call me Nostradamus, but I called this.
Officials see Pfizer’s pill, and another by Merck, as potential gamechangers to tame the pandemic.
Freedom of Information Act requests are rarely speedy, but when a group of scientists asked the federal government to share the data it relied upon in licensing Pfizer’s COVID-19 vaccine, the response went beyond typical bureaucratic foot-dragging.
55 years and longer.
That’s how long the Food & Drug Administration in court papers this week proposes it should be given to review and release the trove of vaccine-related documents responsive to the request. If a federal judge in Texas agrees, plaintiffs Public Health and Medical Professionals for Transparency can expect to see the full record in 2076.
“Fountain is an example of a biotech company emerging as a direct result of basic research, in this case the biology of aging,” said Dr Rando, founder and chairman of Fountain. “The company’s screening and discovery platform is built upon foundational research showing that the age of a cell can be modulated by factors in the cell’s environment. By identifying compounds that work through these pathways, we seek to restore youthful resilience to cells and tissues, leading to therapies that treat or even prevent chronic diseases of aging.”
Longevity funding: Eli Lilly and R42 Group join the party as Khosla-backed biopharma brings total Series A to $26 million.
Every one of us has a magical tool in our pockets or purses. We should be able to enter an unknown building, navigate to our desired location, know where the elevators are, and gain access seamlessly.
But we can’t.
Our buildings cost millions or even billions of dollars. They have the latest technology. But they don’t know how many people are in them. They don’t know when to turn the lights off, or learn when to start warming or cooling office or meeting space. They don’t reposition elevators for maximum efficiency, and they can’t tell first responders where the fire is, where the medical emergency is, or what the quickest route up is. Nor can they tell occupants that the air is clean today, or that there’s an elevated level of volatile organic compounds because the floors were just waxed yesterday.
Fundamental Research On Ethical & Trustworthy Artificial Intelligence, For Health, Environment, And A Sustainable Future — Dr. Patrick van der Smagt, Ph.D., Director, ArtificiaI Intelligence Research, Volkswagen.
Dr. Patrick van der Smagt is Director of ArtificiaI Intelligence Research, Volkswagen AG, and Head of Argmax. AI (https://argmax.ai/), the Volkswagen Group Machine Learning Research Lab, in Munich, focusing on a range of research domains, including probabilistic deep learning for time series modelling, optimal control, reinforcement learning robotics, and quantum machine learning.
Dr. van der Smagt is also a research professor in the Computer Science faculty at Eötvös Loránd University in Budapest.
Dr. van der Smagt previously directed a lab as professor for machine learning and biomimetic robotics at the Technical University of Munich while leading the machine learning group at the research institute fortiss, and before that, founded and headed the Assistive Robotics and Bionics Lab at DLR, the German Aerospace Center.
Besides publishing numerous papers and patents on machine learning, robotics, and motor control, Dr. van der Smagt has won a number of awards, including the 2013 Helmholtz-Association Erwin Schrödinger Award, the 2014 King-Sun Fu Memorial Award, the 2013 Harvard Medical School/MGH Martin Research Prize, the 2018 Webit Best Implementation of AI Award, and best-paper awards at various machine learning and robotics conferences and journals.
A chemist in D.C.’s crime lab has discovered a new synthetic opioid being used on the streets of the District. The lab immediately alerted first responders about the possibility the drug could be resistant to the lifesaving antidote Narcan.
As part of her work testing used syringes to surveil the drug supply for new threats, chemist Alexandra Evans discovered the first known sample of Protonitazene in D.C.
Google is secretly working with the world’s leading neuroscientists on mapping the entire Human Brain. Neuroscientists at have released the most detailed 3D map of the mammalian brain ever made. Google has helped them by funding their goal to create the most detailed map yet of the connections within the human brain. It reveals a staggering amount of detail, including patterns of connections between neurons, as well as what may be a new kind of neuron.
The applications in the field of Brain Computer Interfaces or understanding medical conditions are staggering. But it’s doubtful that this will just help companies such as Neuralink develop advanced future brain computer interfaces and will likely lead to Google doing evil things by understanding people’s way of thinking and delivering ads to them.
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TIMESTAMPS:
00:00 A Paradigm Shift in Brain Research.
00:53 What did actually happen?
02:54 How Scientists mapped the Human Brain.
05:05 What this does for neuroscientists.
06:23 How long until we understand the Brain?
08:08 Last Words.
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#google #bci #neuralink
Nvidia (NVDA) CEO Jensen Huang doesn’t see the global chip shortage coming to an end anytime soon. The head of the largest chip maker by market cap, Huang is fresh off his virtual keynote at Nvidia’s GTC conference where he announced advances in the company’s metaverse and AI efforts.
But Nvidia still makes the bulk of its revenue, about 47% in Q2, from the sale of its gaming cards. And those continue to be in short supply due to the pandemic-induced chip crisis.
“I think that through the next year, demand is going to far exceed supply. We don’t have any magic bullets in navigating the supply chain,” Huang told Yahoo Finance Live on Wednesday.
For example, scientists recently treated a patient’s severe depression with a neural implant that zaps her brain 300 times per day and, she says, has allowed her to spontaneously laugh and feel joy for the first time in years. Of course, the treatment requires an electrode implanted deep into the brain, which currently reserves it for the most extreme medical cases — but as brain interface tech inexorably becomes more advanced and widely available, there’s no reason such a device couldn’t become a consumer gadget as well.
At the research’s current rate of trajectory, experts told Futurism, the tech could conceivably hit the market in just a few years. But what we don’t know is what it will mean for us, psychologically as individuals and sociologically as a society, when we can experience genuine pleasure from the push of a button. And all those questions become even more complex, of course, when applied to the messy world of sex.
“A big question that remains unanswered is whether sextech will ultimately become a complement to our sex lives or a substitute,” Kinsey Institute research fellow Justin Lehmiller, an expert on sex and psychology, told Futurism.
Incredible new videos show stem cells escaping from hair follicles, which could provide insight on a new, potentially reversible mechanism of hair loss.
Stem cells contribute to tissue regeneration, and they are thought to play an important role in age-related decline — so much so that stem cell exhaustion is one of the hallmarks of aging. These stem cells reside in “compartments” in various tissues. In the hair, the stem cell compartment, known as the bulge, is adjacent to the hair follicle.
It is extremely hard to monitor stem cell activity in live animals over time, yet this is exactly what the researchers of this study have achieved using noninvasive imaging techniques based on lasers. By anesthetizing mice and putting them inside the imaging device, they were able to observe and record the process of stem cells escaping their compartment.
Researchers watched as escaping stem cells changed their shape and shot out of the compartment as if squeezing through invisible holes, which are most likely structural abnormalities in the membrane. The researchers hypothesize that aging somehow harms the structural integrity of the membrane, but this phenomenon demands further examination. The “rogue” stem cells escape to the dermis, which is the lower layer of the skin. Once there they remained stem cells, and seemed to be doing quite well in the new environment. However, this may not be a good sign, since stem cells are known to contribute heavily to tumorigenesis, and the authors call for more research into the role that escaping stem cells might play in the development of cancer.
The researchers studied both young and old mice. In young animals, the stem cell compartment was well defined, and cells were restricted to their rightful place. In many older mice, however, the researchers noticed the shrinkage of the hair follicle and compartment. The shrinkage was even more pronounced when the compartment showed signs of stem cell escape.
The researchers looked for proteins that were downregulated in the follicles that experienced stem cell escape, zeroing in on two transcription factors (FOXC1 and NFATC1). These identified proteins are indeed known to regulate cellular adhesion and extracellular matrix integrity.