Toggle light / dark theme

The advance is unique: the patients have used a mind-controlled prosthesis in their everyday life for up to seven years. For the last few years, they have also lived with a new function – sensations of touch in the prosthetic hand. This is a new concept for artificial limbs, which are called neuromusculoskeletal prostheses – as they are connected to the user’s nerves, muscles, and skeleton.

In the week of April 12–18, the top 10 search terms on Amazon.com were: toilet paper, face mask, hand sanitizer, paper towels, Lysol spray, Clorox wipes, mask, Lysol, masks for germ protection, and N95 mask. People weren’t just searching, they were buying too —and in bulk. The majority of people looking for masks ended up buying the new Amazon #1 Best Seller, “Face Mask, Pack of 50”.

When covid-19 hit, we started buying things we’d never bought before. The shift was sudden: the mainstays of Amazon’s top ten—phone cases, phone chargers, Lego—were knocked off the charts in just a few days. Nozzle, a London-based consultancy specializing in algorithmic advertising for Amazon sellers, captured the rapid change in this simple graph.

It took less than a week at the end of February for the top 10 Amazon search terms in multiple countries to fill up with products related to covid-19. You can track the spread of the pandemic by what we shopped for: the items peaked first in Italy, followed by Spain, France, Canada, and the US. The UK and Germany lag slightly behind. “It’s an incredible transition in the space of five days,” says Rael Cline, Nozzle’s CEO. The ripple effects have been seen across retail supply chains.

Scientists at the Kennedy Institute of Rheumatology in the Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences have discovered a new way for T cells to attack cells infected by viruses or deranged by cancer.

Published online by the journal Science on Thursday 7 May 2020, the new research from the Dustin Group describes the structure and composition of supramolecular attack particles (SMAPs) and their role in killing targeted .

Cytotoxic T lymphocytes (CTLs) are essential components in the immune response against viruses and cancer. CTLs are known to recognise infected or damaged cells and release soluble protein molecules, which create perforations in the membrane of the targeted cell. These holes allow toxic enzymes to enter and initiate a self-destruct program, killing the targeted cell (cytotoxicity).

As expected, they discovered large fluctuations in the composition and daily changes of the human and mouse gut microbiomes. But strikingly, these apparently chaotic fluctuations followed several elegant ecological laws.

“Similar to many animal ecologies and complex financial markets, a healthy gut microbiome is never truly at equilibrium,” Vitkup says. “For example, the number of a particular bacterial species on day one is never the same on day two, and so on. It constantly fluctuates, like stocks in a financial market or number of animals in a valley, but these fluctuations are not arbitrary. In fact, they follow predictable patterns described by Taylor’s power law, a well-established principle in animal ecology that describe how fluctuations are related to the relative number of bacteria for different species.”

Other discovered laws of the gut microbiome also followed principles frequently observed in animal ecologies and economic systems, including the tendency of gut bacteria abundances to slowly but predictably drift over time and the tendency of species to appear and disappear from the gut microbiome at predictable times.

“It is amazing that microscopic biological communities—which are about six orders of magnitude smaller than macroscopic ecosystems analyzed previously—appear to be governed by a similar set of mathematical and statistical principles,” says Vitkup.

Laws allow identification of abnormal bacterial behavior.

Researchers at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan have identified changes in the aging brain related to blood circulation. Published in the scientific journal Brain, the study found that natural age-related enlargement of the ventricles—a condition called ventriculomegaly—was associated with a lag in blood drainage from a specific deep region of the brain. The lag can be detected easily with MRI, making it a potential biomarker for predicting ventriculomegaly and the aging brain, which can then be treated quickly.

Ventriculomegaly is an abnormal condition in which fluid accumulates in the ventricles of the without properly draining, making them enlarged. Although ventricular enlargement within normal range is not itself considered a disease, when left unchecked it can lead to ventriculomegaly and dementia resulting from normal pressure hydrocephalus. In their study, the team found that ventriculomegaly was associated with changes in circulation of the brain. “We found an age-related perfusion timing shift in the brain’s venous systems whose lifespan profile was very similar to, but slightly preceded that of ventricular enlargement,” explains first author Toshihiko Aso.

After blood circulates through the brain providing necessary oxygen, the deoxygenated blood must return to the heart though our veins. This happens through two pathways, one draining blood from regions close to the surface of the brain, and the other from areas deep in the brain. By using MRI to measure changes in , the team at BDR recently found that as we age, the time it takes for blood to drain through these two pathways becomes out of sync. The result is a time lag between the deep drainage and the surface pathway, which increases with age.

TEL AVIV, Israel, April 22, 2020 /PRNewswire/ — Prof. Dedi (David) Meiri, Chairman and CSO of CannaSoul and Nadav Eyal, Co-founder and CEO of Eybna Technologies Ltd, announced today the companies have jointly engaged in a mutual assays of CannaSoul’s (through its Myplant-Bio subsidiary) Cytokine Storm Assay and Eybna’s Novel NT-VRL™ formulation dedicated for treatment and prevention of viral infections — specifically for high-risk populations and treatment of actively ill patients.