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Christian Angermayer on longevity and biotech investment

Christian Angermayer, founder of talks longevity investment, optimism on SPAC deal and light at the end of the tunnel for the biotech market.
One of the speakers at October’s Rejuvenation Startup Summit in Berlin is the entrepreneur and investor, Christian Angermayer.

With more than $3 billion under management through his Apeiron Investment Group, Angermayer is a major figure in the longevity sector through his platform biotech companies Cambrian and Rejuveron – building on his belief that everyone wants to live healthier, happier and longer lives.

Ahead of Berlin’s meeting, our editor-in-chief caught up with Angermayer for a video interview in which he shares his views on subjects ranging from longevity investing, the biotech market, and what’s happening with his $200 million SPAC with David Sinclair and Peter Attia.

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Boosting Neuron Formation Restores Memory in Mice With Alzheimer’s Disease

Summary: Increasing neurogenesis by deleting the Bax gene in mouse models of Alzheimer’s improved the animals’ performance in tests measuring spatial recognition and contextual memory.

Source: Rockefeller University.

Researchers at the University of Illinois Chicago have discovered that increasing the production of new neurons in mice with Alzheimer’s disease (AD) rescues the animals’ memory defects.

New Method Enables Long-Lasting Imaging of Rapid Brain Activity in Individual Cells Deep in the Cortex

Summary: Researchers have developed a new sensor that allows scientists to image the brain without missing signals for an extended period of time and deeper in the brain than current technology allows.

Source: Baylor College of Medicine.

As you are reading these words, certain regions of your brain are displaying a flurry of millisecond-fast electrical activity. Visualizing and measuring this electrical activity is crucial to understand how the brain enables us to see, move, behave or read these words.

New Research Shows How Dopamine Plays a Key Role in Consciousness

The Brain Chemical Involved in Consciousness

So how do we help these people? The brain is more than just a congregation of different areas. Brain cells also rely on a number of chemicals to communicate with other cells, enabling a number of brain functions. Before our study, there was already some evidence that dopamine, well known for its role in reward, also plays a role in disorders of consciousness.

For example, one study showed that dopamine release in the brain is impaired in minimally conscious patients. Moreover, a number of small-scale studies have shown that patients’ consciousness can improve by giving them drugs that act through dopamine.

Scientists design new inks for 3D-printable wearable bioelectronics

Flexible electronics have enabled the design of sensors, actuators, microfluidics and electronics on flexible, conformal and/or stretchable sublayers for wearable, implantable or ingestible applications. However, these devices have very different mechanical and biological properties when compared to human tissue and thus cannot be integrated with the human body.

A team of researchers at Texas A&M University has developed a new class of biomaterial inks that mimic native characteristics of highly conductive , much like skin, which are essential for the ink to be used in 3D printing.

This biomaterial ink leverages a new class of 2D nanomaterials known as molybdenum disulfide (MoS2). The thin-layered structure of MoS2 contains defect centers to make it chemically active and, combined with modified gelatin to obtain a flexible hydrogel, comparable to the structure of Jell-O.

Mind-Reading Neural Network Uses Brain Waves to Recreate Human Thoughts

And these miniaturized brains could save regular-sized brains.

Electroencephalography (EEG) caps are medical devices doctors use to diagnose brain disorders like epilepsy and seizures in patients. In the past decade, scientists have created 3D mini-brains called brain organoids from human-derived stem cells that mimic some aspects of brain development. A team of researchers at John Hopkins University has recently developed the world’s smallest EEG caps to study these more efficiently. The micro EEG caps can be used on a brain organoid the size of a pen dot.

Brain organoids can mimic some key features of the human brain. Scientists create them to understand the human brain’s development process and the factors leading to various neural disorders. Moreover, such mini-brains can also be used to perform experiments that researchers would have to otherwise perform on a real brain. Thus, eliminating the need to conduct tests on live human and animal subjects. has long been the stuff of science fiction but now mind-reading machines may actually be here and they may not be invasive. Researchers from the Russian corporation Neurobotics and the Moscow Institute of Physics and Technology have found a way to visualize a person’s brain activity as actual images without the use of invasive brain implants.

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