Scientists around the world are working on a number of vaccines and treatments for COVID-19.
Category: biotech/medical – Page 1714
A team of scientists successfully achieved 53% reverse aging in old rats with blood plasma from young rats, in an astounding leap forward for the erstwhile-controversial aging field of study.
Kim Jong-un has not been seen since May 1 (Image: GETTY)
Claims carried in numerous media outlets last month suggested the 36-year-old had died after botched heart surgery, or was alternatively in a vegetative state.
Speculation was fuelled after he missed the birth anniversary celebrations of state founder Kim Il-sung, his grandfather, on April 15.
In a study published today (May 13, 2020) in the New England Journal of Medicine, scientists in the U.S. and Japan report that in the laboratory, cats can readily become infected with SARS-CoV-2, the virus that causes COVID-19, and may be able to pass the virus to other cats.
Professor of Pathobiological Sciences at the University of Wisconsin School of Veterinary Medicine Yoshihiro Kawaoka led the study, in which researchers administered to three cats SARS-CoV-2 isolated from a human patient. The following day, the researchers swabbed the nasal passages of the cats and were able to detect the virus in two of the animals. Within three days, they detected the virus in all of the cats.
The day after the researchers administered virus to the first three cats, they placed another cat in each of their cages. Researchers did not administer SARS-CoV-2 virus to these cats.
Doctors regularly warn their patients that having high levels of triglycerides, a major dietary fat, can increase the risk of heart disease, diabetes, obesity and fatty liver disease. There is considerable interest in finding novel ways to effectively regulate triglycerides in the blood to help manage these potentially life-threatening common conditions.
Now, researchers at Baylor College of Medicine, Princeton University and Texas A&M University are closer to achieving this goal after discovering the 3D structure and mode of action of diacylglycerol O-acyltransferase-1 (DGAT1), the enzyme that synthesizes triglycerides and also is required for human dietary fat absorption and storage. DGAT1 is a known target to treat obesity and other metabolic diseases, so having a detailed understanding of what DGAT1 looks like and how it works opens opportunities for designing novel strategies for managing these conditions. The findings are published in the journal Nature.
“DGAT1 is a particularly interesting enzyme because it synthesizes triglycerides, which are the main component of hard fat, the type of fat usually found in the belly or midsection in our body. Triglycerides also are part of the particles that transport cholesterol—high-density lipoproteins (HDL, or ‘good cholesterol’), and low-density and very-low-density lipoproteins (LDL and VLDL, or ‘bad cholesterols’),” said co-corresponding author Dr. Ming Zhou, Ruth McLean Bowman Bowers Professor in Biochemistry in the Department of Biochemistry and Molecular Biology at Baylor. “Learning to regulate this enzyme can help regulate fat synthesis and potentially manage related conditions.”
The 42-year-old virologist and epidemiologist, who has responded to multiple outbreaks around the world, got sick about three days after a flight to his home in New Orleans.
“I had a mask on, I had gloves on, I did my normal wipes routine … but obviously, you can still get it through your eyes,” Fair said on the “TODAY” show from his hospital bed. “And of course I wasn’t wearing goggles on the flight.”
“That’s one of the three known routes of getting this infection that we just don’t pay a lot of attention to; we tend to pay attention to the nose and mouth because that is the most common route,” he said. “But you know, droplets landing on your eyes are just as infectious.”
This could essentially in the wrong hands be very bad but in the positive ways it could cure anything.
Right now the world is at war. But this is no ordinary war. It’s a fight with an organism so small we can only detect it through use of a microscope — and if we don’t stop it, it could kill millions of us in the next several decades. No, I’m not talking about COVID-19, though that organism is the one on everyone’s mind right now. I’m talking about antibiotic-resistant bacteria.
You see, more than 700,000 people died globally from bacterial infections last year — 35,000 of them in the U.S. If we do nothing, that number could grow to 10 million annually by 2050, according to a United Nations report.
The problem? Antibiotic overuse at the doctor’s office or in livestock and farming practices. We used a lot of drugs over time to kill off all the bad bacteria — but it only killed off most, not all, of the bad bacteria. And, as the famous line from Jeff Goldblum in Jurassic Park goes, “life finds a way.”
A group of tiny RNA that should attack the virus causing COVID-19 when it tries to infect the body are diminished with age and chronic health problems, a decrease that likely helps explain why older individuals and those with preexisting medical conditions are vulnerable populations, investigators report.
MicroRNAs play a big role in our body in controlling gene expression, and also are a front line when viruses invade, latching onto and cutting the RNA, the genetic material of the virus, says Dr. Sadanand Fulzele, aging researcher in the Department of Medicine and Center for Healthy Aging at the Medical College of Georgia at Augusta University.
But with age and some chronic medical conditions, the attacking microRNA numbers dwindle, reducing our ability to respond to viruses, says Dr. Carlos M. Isales, co-director of the MCG Center for Healthy Aging and chief of the MCG Division of Endocrinology, Diabetes and Metabolism.
“” What we thought would be fringe is actually the core,” Johnson explains.”
Anti-vaccine groups flourished during the 2019 measles pandemic. They may flourish during the 2020 coronavirus pandemic using those same key strategies.
South Korea has typically released information like a patient’s age, gender, and places visited immediately before testing positive, as well as in some cases, patients’ last names and general occupations.
About 2,000 people are still being sought by officials.
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