“Social robots like me can take care of the sick or elderly,” Sophia says as she conducts a tour of her lab in Hong Kong. “I can help communicate, give therapy and provide social stimulation, even in difficult situations.”
Category: biotech/medical – Page 1,658
Government-backed incentives and funding are still the main engines driving Chinese manufacturers to replace humans with robots in industries including pharmaceuticals, medical devices, new infrastructure projects and food processing.
Trade war with US saw many companies relocate outside China, but orders came back last year as Chinese production rapidly rebounded from the coronavirus, and a robotics boom is expected in 2021.
Fair to say that we all assume that aging is inevitable. In reality however, there is no biological law that says we must age. Over the years we’ve seen a variety of theories proposed to explain why we age including the accumulation of damage to our DNA, the damaging effects of chemicals called “free radicals, changes in the function of our mitochondria, and so many others.
Our guest today, Dr. David Sinclair, believes that aging is related to a breakdown of information. Specifically, he describes how, with time, our epigenome accumulates changes that have powerful downstream effects on the way our DNA functions. Reducing these changes to the epigenome is achievable and in fact, even taking it further, his research now reveals that the epigenome can be reprogrammed back to a youthful state.
David A. Sinclair, PhD, AO is Professor of Genetics at Harvard Medical School, and is the author of Lifespan — Why We Age and Why We Don’t Have To. He is the Founding Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging at Harvard. One of the leading innovators of his generation, he is listed by TIME magazine as one of the “100 most influential people in the world” (2014) and top 50 most important people in healthcare (2018). He is a board member of the American Federation for Aging Research, a Founding Editor of the journal Aging, and has received more than 35 awards for his research on resveratrol, NAD, and reprogramming to reverse aging, which have been widely hailed as major scientific breakthroughs and are topics we discuss in our time together.
In 2018, Dr. Sinclair became an Officer of the Order of Australia, the equivalent of a knighthood, for his work on national security matters and human longevity. Dr. Sinclair and his work have been featured on 60 Minutes, Today, The Wall Street Journal, The New York Times, Fortune, and Newsweek, among others.
In closing, I really need to say that Lifespan (https://amzn.to/3sSoCNS) ranks as one of the most influential books I have ever read. Please enjoy today’s interview.
To stay current on Dr. Sinclair, follow him on Twitter (https://twitter.com/davidasinclair) and Instagram (https://www.instagram.com/davidsinclairphd/)
Ditto for Canada…
As US President Biden signs a national mask mandate into law, measures being imposed in the name of protecting public health could create a humanitarian crisis that sees Americans sued by the state and forced into detention camps for breaking pandemic protocols.
The very first executive order Joe Biden signed upon becoming the forty-sixth President of the United States was the national mask mandate he promised at the Democratic National Convention back in August. The order makes face coverings and social distancing mandatory on all federal property and a legal requisite for interstate commerce.
MONTREAL — A team of researchers from the Montreal Heart Institute believe they have found an effective weapon against COVID-19: colchicine, an oral tablet already known and used for other diseases.
For Dr. Jean-Claude Tardif, who led the study, this is a “major scientific discovery,” he said. Colchicine is the first “effective oral drug to treat out-of-hospital patients.”
“To be able to offer this, from Quebec, and for the planet, we are very happy,” said Tardif.
DNA Storage Goes Biological
Posted in biotech/medical
Intelligent Design
DNA is already known to be an ideal storage medium. Why not use cells to do the hard work?
Oneskin — the first skin cream that destroys senescent cells:
Longevity, Health, Long Lifespans, and Halthspans, Psychology, Spirituality — I and Carolina Reis Oliveira talk about all these things in relation to the skin. Find out how you can have very healthy skin with OneSkin!
Visit OneSkin’s website — https://www.oneskin.co/
0:00 — Logo & Title.
0:17 — H! & Intro.
1:40 — Presentation.
2:20 — Presentation | Skin Health — Longevity.
3:57 — Presentation | The Root Cause of Aging.
4:46 — Presentation | Senescent Cells.
5:49 — Presentation | Current solutions.
6:32 — Presentation | OneSkin Approach.
7:47 — Presentation | Let’s Dive Deeper into the Science.
9:51 — Presentation | Replicating Skin Aging.
11:42 — Presentation | Developing an Algorithm to Measure Skin Aging.
12:58 — Presentation | A Drug Discovery Process.
14:23 — Presentation | Senotherapeutic Compounds.
15:00 — Presentation | OS1
15:42 — Presentation | OS1 & UVB Radiation.
17:13 — Presentation | OS1 — Validate effects in 3D models.
19:33 — Presentation | OS1 — Treatment in Skin Biopsies.
20:55 — Presentation | OS1 — Safety.
21:43 — Presentation | OS1 — Clinical Study Results.
23:18 — Presentation | OS1 — Applications Beyond Skin.
26:14 — Presentation | Team.
28:07 — Q&A + the Conversation.
28:25 — Futuristic Psychology & Spirituality.
31:34 — Myths Regarding Immortality.
34:20 — The Collective Rejuvenation.
37:10 — Biologic Hygiene.
41:56 — Cellular Senescence.
46:00 — The Molecular Clock.
48:04 — Morphogenesis of a Scar.
51:15 — Differences Between Skin Types on a Body.
52:35 — Skin Types Regarding Different Races.
54:44 — Skin Conditions.
56:03 — Closing & Ending
Essentially nearly all the animals are fine and plants too just humans are affected by the virus.
When COVID hit New York and the city shut down, it upended life for rats, too. But, like always, they’ve adjusted.
Prostate cancer is one of the most common cancers among men. Patients are determined to have prostate cancer primarily based on PSA, a cancer factor in blood. However, as diagnostic accuracy is as low as 30%, a considerable number of patients undergo additional invasive biopsy and thus suffer from resultant side effects, such as bleeding and pain.
The Korea Institute of Science and Technology (KIST) announced that the collaborative research team led by Dr. Kwan Hyi Lee from the Biomaterials Research Center and Professor In Gab Jeong from Asan Medical Center developed a technique for diagnosing prostate cancer from urine within only 20 minutes with almost 100% accuracy. The research team developed this technique by introducing a smart AI analysis method to an electrical-signal-based ultrasensitive biosensor.
As a noninvasive method, a diagnostic test using urine is convenient for patients and does not need invasive biopsy, thereby diagnosing cancer without side effects. However, as the concentration of cancer factors is low in urine, urine-based biosensors are only used for classifying risk groups rather than for precise diagnosis thus far.
The maximal reduction for biological age when using the biological age calculator, Phenotypic Age, is ~20 years. In other words, if I’m 80 years old and my biomarkers are all reflective of youth, the lowest possible biological age will be ~60 years old. One reason for that is the inclusion of chronological age in the prediction of biological age, which adds strength to the correlation while simultaneously limiting the maximal biological age reduction.
To account for the possibility that youthful biomarkers at an older chronological age can yield a biological age that is more than 20 years younger, it’s important to quantify biological age using a tool that doesn’t include chronological age in its calculation. Aging.ai fits that criterion, and in the video I present biological age data with use of aging.ai for 24 blood tests since 2009.