Little Kurt looks like any other baby horse as he frolics playfully in his pen. He isn’t afraid to kick or head-butt an intruder who gets in his way and, when he’s hungry, dashes over to his mother for milk.

But 2-month-old Kurt differs from every other baby horse of his kind in one distinct way: He’s a clone.

The rare, endangered Przewalski’s horse was created from cells taken from a stallion that had sat frozen at the San Diego Zoo for 40 years before they were fused with an egg from a domestic horse.

In the largest clinical trial of its kind, researchers show that combining sound and electrical stimulation of the tongue can significantly reduce tinnitus, commonly described as “ringing in the ears.” They also found that therapeutic effects can be sustained for up to 12 months post-treatment.

The findings could potentially help millions of people since tinnitus affects about 10 to 15 percent of the population worldwide. The study was conducted by researchers from the University of Minnesota, Trinity College, St. James’s Hospital, University of Regensburg, University of Nottingham, and Irish medical device company Neuromod Devices Limited.

The research was published as the cover story of Science Translational Medicine, an interdisciplinary medical journal by the American Association for the Advancement of Science (AAAS).

🤔 (CNN)In a study it described as both conclusive and disappointing, the World Health Organization said the antiviral drug remdesivir has “little or no effect on mortality” for patients hospitalized with coronavirus and it doesn’t seem to help patients recover any faster, either.

Until now, remdesivir has been the only drug that appeared to have specific effects for coronavirus. It was the only drug with an Emergency Use Authorization for Covid-19 from the US Food and Drug Administration.

Results of the WHO study have not been published in a peer-reviewed medical journal.🙄 But WHO posted them to a pre-print server.

More than half of the world’s population carries the bacterium Helicobacter pylori in their stomach mucosa. It often causes no problems throughout life, but sometimes it can cause inflammation, and in some cases, it can even lead to the development of stomach cancer.

Helicobacter pylori uses several ‘virulence’ factors that allow it to survive in the stomach and can lead to the development of disease. In this issue of the journal Molecular Cell, Professor Cynthia Sharma’s research team report that multiple of these factors are centrally regulated by a small RNA molecule called NikS. Prof. Sharma heads the Chair for Molecular Infection Biology II at Julius-Maximilians-Universität (JMU) Würzburg in Bavaria, Germany.

Among the target genes regulated by NikS are the two most important virulence factors of Helicobacter pylori as well as two encoding outer membrane proteins. In particular, the JMU researchers were able to show that NikS regulates the CagA protein, a bacterial oncoprotein that plays a central role in the development of cancer instigated by Helicobacter pylori. In addition, a protein with a so far unknown function that is released into the environment by H. pylori is also under the control of NikS.