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Category: biotech/medical – Page 1350

Pear-shaped people, whose weight is generally distributed more evenly, rather than “apple shaped” individuals with fat clustered around their middle and often around internal organs like the liver in the abdominal cavity, are considered less at risk for cardiometabolic problems like heart disease and diabetes, as well as cognitive decline, says Stranahan, neuroscientist at the Medical College of Georgia at Augusta University.

Summary: Adipocytes, or beige fat cells, are indispensable to the anti-inflammatory and neuroprotective effects of subcutaneous fat, researchers say.

Source: Medical College of Georgia at Augusta University

Beige is considered a calming paint color, and scientists have new evidence that beige fat has a similar impact on the brain, bringing down the inflammation associated with the more common white fat and providing protection from dementia.

Continue reading “Beige Fat “Indispensable” in Protecting the Brain From Dementia” | >

When the resulting paste is applied to a wet surface such as blood-covered tissue, the oil repels the blood and other substances that may be present, allowing the adhesive microparticles to crosslink and form a tight seal over the wound. Within 15 to 30 seconds of applying the glue, with gentle pressure applied, the glue sets and bleeding stops, the researchers showed in tests in rats.

A new adhesive that mimics the sticky substance barnacles use to cling to rocks may offer a better way to treat traumatic injuries.

Inspired by the sticky substance that barnacles use to cling to rocks, MIT

MIT is an acronym for the Massachusetts Institute of Technology. It is a prestigious private research university in Cambridge, Massachusetts that was founded in 1861. It is organized into five Schools: architecture and planning; engineering; humanities, arts, and social sciences; management; and science. MIT’s impact includes many scientific breakthroughs and technological advances.

Continue reading “Bio-Inspired, Blood-Repelling Tissue Glue Can Seal Wounds Quickly and Stop Bleeding” | >

The Astronomy, Technology, and Space Science News Podcast.
SpaceTime Series 24 Episode 91
*Astronomers zero in on source of the impactor that wiped out the dinosaurs.
A new study claims the impactor believed to have wiped out and 75 percent of all life on Earth 66 million years ago including all the non-avian dinosaurs — likely came from the outer half of the main asteroid belt between Mars and Jupiter.
*Producing matter out of pure energy.
Scientists have directly converted pure light energy into matter in a single process for the first time.
The findings reported in the journal Physical Review Letters involved the creation of Electrons and their antimatter counter parts positrons — by colliding quantum packets of photons – light particles.
*Discovery of a galactic stream of galaxy clusters.
Astronomers have discovered a never-before-seen galaxy cluster with a black hole at its centre, travelling at high speed along an intergalactic road of matter.
*Solar Orbiter and BepiColombo making space history with double flyby of Venus.
As we go to air tonight the European Space Agency is making space history with two of its space craft6 undertaking almost simultaneous flybys of the planet Venus.
*The Science Report.
New US congressional report says COVID-19 leaked out of Chinese Government Wuhan Lab.
Wearing masks and social distancing even when vaccinated key to combat new COVID strains.
Rising sea levels may mean fewer eruptions from volcanic islands.
How slowing of the planet’s rotation could have paved the way for life on Earth.
Skeptic’s guide to low vaccination and low IQ.
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Researchers at CU Boulder have developed a platform which can quickly identify common mutations on the SARS-CoV-2 virus that allow it to escape antibodies and infect cells.

Published today in Cell Reports, the research marks a major step toward successfully developing a universal vaccine for not only COVID-19, but also potentially for influenza, HIV and other deadly global viruses.

“We’ve developed a predictive tool that can tell you ahead of time which antibodies are going to be effective against circulating strains of virus,” said lead author Timothy Whitehead, associate professor of chemical and biological engineering. “But the implications for this technology are more profound: If you can predict what the variants will be in a given season, you could get vaccinated to match the sequence that will occur and short-circuit this seasonal variation.”

Researchers have developed a platform which can quickly identify common mutations on the SARS-CoV-2 virus that allow it to escape antibodies and infect cells, which could inform the development of more effective booster vaccines and tailored antibody treatments for patients with COVID-19.

Continue reading “Mutation-mapping tool could yield stronger COVID boosters, universal vaccines” | >

Circa 2018

Mechanical loading is an important cue for directing stem cell fate and engineered tissue formation in vitro. Stem cells cultured on 2-dimensional (D) substrates and in 3D scaffolds have been shown to differentiate toward bone, tendon, cartilage, ligament, and skeletal muscle lineages depending on their exposure to mechanical stimuli. To apply this mechanical stimulus in vitro, mechanical bioreactors are needed. However, current bioreactor systems are challenged by their high cost, limited ability for customization, and lack of force measurement capabilities. We demonstrate the use of 3-dimensional printing (3DP) technology to design and fabricate a low-cost custom bioreactor system that can be used to apply controlled mechanical stimuli to cells in culture and measure the mechanical properties of small soft tissues. The results of our in vitro studies and mechanical evaluations show that 3DP technology is feasible as a platform for developing a low-cost, customizable, and multifunctional mechanical bioreactor system.

• 3DP technology was used to print a multifunctional bioreactor system/tensile load frame for a fraction of the cost of commercial systems.

• The system mechanically stimulated cells in culture and evaluated the mechanical properties of soft tissues.

Continue reading “A 3D printed mechanical bioreactor for investigating mechanobiology and soft tissue mechanics” | >