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Leveraging big data & artificial intelligence to solve unmet medical needs — andrea de souza — eli lilly & co.


Andrea De Souza, is Associate Vice President, Research Data Sciences and Engineering, at Eli Lilly & Company (https://www.lilly.com/) where over the past three years her work has focused around empowering the Lilly Research Laboratories (LRL) organization with greater computational, analytics-intense experimentation to raise the innovation of their scientists.

A former neuroscience researcher, Andrea’s portfolio career has included leadership assignments at the intersection of science, technology and business development. She has built and led informatics and scientific teams across the entire pharmaceutical value chain.

Most recently, Andrea focused on building the Pharma Artificial Intelligence market at NVIDIA. Through this experience she has traveled the world advising bio-pharmaceutical clients, academics, research institutes, and startups in the potential of machine learning and artificial intelligence across every discipline of the industry.

Prior to her role at NVIDIA, Andrea held leadership positions at the Broad Institute of Harvard and MIT, Amgen, and Roche.

Researchers at the University of Liverpool have captured a clear view of the generation process of “protein machinery” that plays a key role in the colonization of pathogenic Salmonella bacteria.

The findings, published in Nature Communications, answer an important question about how various proteins self-assemble to create a higher-ordered functional organelle in Salmonella to boost metabolism.

Many , such as Salmonella, use specialized nano-sized organelles, or bacterial microcompartments (BMC). The BMC has a virus-like polyhedral shell made of proteins to encase multiple metabolic cargo enzymes. The protein shell provides a selectively permeable barrier which controls the passage of metabolites and sequesters the reactions in its interior. This ensures higher efficiency of the encapsulated reactions and prevents toxic products from being released into the rest of the cell, providing the pathogens a competitive advantage in human gut.

Having multiple conditions that affect the heart are linked to a greater risk of dementia than having high genetic risk, according to a largescale new study.

Led by Oxford University and the University of Exeter, the study is among the largest ever to examine the link between several heart-related conditions and dementia, and one of the few to look at the complex issue of multiple health conditions.

Published in The Lancet Healthy Longevity, the paper looked at data from more than 200,000 people, aged 60 or above, and of European ancestry in UK Biobank. The international research team identified those who had been diagnosed with the cardiometabolic conditions diabetes, stroke, or a heart attack, or any combination of the three, and those who went on to develop dementia.

Jeffrey DeanUnless you’re actively scrubbing the co2, that’s what happens when you recirculate air.

James FalkA carbonator?

Michael Taylor shared a link.


A horse, a zebra and artificial intelligence helped a team of Carnegie Mellon University researchers teach a robot to recognize water and pour it into a glass.

Water presents a tricky challenge for robots because it is clear. Robots have learned how to pour before, but previous techniques like heating the water and using a thermal camera or placing the glass in front of a checkerboard background don’t transition well to everyday life. An easier solution could enable servers to refill water glasses, robot pharmacists to measure and mix medicines, or robot gardeners to .

New artificial skin for bionic arm or AI robot | breakthrough photonic chip processes 2 billion images per second without memory device.


AI news includes new artificial skin to let AI robot, bionic arm or prosthetic limb feel with extreme touch sensitivity. New photonic chip allows AI to process and classify 2 billion images per second without needing storage device.

AI News Timestamps:
0:00 AI Robot Artificial Skin For Bionic Arm.
3:28 Photonic Chip Processes 2 Billion Images / Second.

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Developer Documentation — https://dev.singularitynet.io/
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#AI #Robot #Bionic

Several years ago, a promising therapeutic using stem cell factor (SCF) emerged that could potentially treat a variety of ailments, such as ischemia, heart attack, stroke and radiation exposure. However, during clinical trials, numerous patients suffered severe allergic reactions and development of SCF-based therapeutics stopped.

A research team led by engineers at The University of Texas at Austin has developed a related therapeutic that they say avoids these major allergic reactions while maintaining its therapeutic activity. The keys to the discovery, published recently in Nature Communications, were the use of a similar, membrane-bound version of SCF delivered in engineered lipid nanocarriers.

“We envision this as something you can inject where you have lack of blood flow and it could induce to grow in that area,” said Aaron Baker, a professor in the Cockrell School of Engineering’s Department of Biomedical Engineering, and one of the leaders on the project.

In celebration of Pride Month, Inara, one of our moderators, is fundraising to pay for her transition surgery. I donated.

Gender dysphoria is the term used to describe a sense of discomfort or distress that a person may experience because of a mismatch between their gender identity and their sex assigned at birth. Methods of relieving gender dysphoria include transitioning socially (pronoun usage, name change, etc.) and physically (surgery).

I have medical insurance but it does not cover trans healthcare. Yes, we are still fighting for trans rights! I need allies willing to take action on my behalf.

To assess whether a compound holds promise for treating a disease, researchers usually begin by studying its use in animals. This allows us to see if the compound has a chance of curing the disease.

Animal models, however, rarely reproduce all aspects of a disease. The alternative is to represent the disease in cell cultures. While at first glance, Petri dishes look quite different from a person with a disease, the reality could be quite different when you look at them more closely.

Alzheimer’s has been cured more than 400 times in laboratories. How then can we still consider Alzheimer’s to be incurable? The reason is that it has only been cured in animals.