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Category: biotech/medical – Page 1314

The story illuminates the way that many scientific discoveries become life-changing innovations: with decades of dead ends, rejections and battles over potential profits, but also generosity, curiosity and dogged persistence against scepticism and doubt. “It’s a long series of steps,” says Paul Krieg, a developmental biologist at the University of Arizona in Tucson, who made his own contribution in the mid-1980s, “and you never know what’s going to be useful”.

Hundreds of scientists had worked on mRNA vaccines for decades before the coronavirus pandemic brought a breakthrough.

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Pandemic lockdown forces a new perspective on designs for futuristic AI-based computing devices.

Isaac Newton’s groundbreaking scientific productivity while isolated from the spread of bubonic plague is legendary. University of California San Diego physicists can now claim a stake in the annals of pandemic-driven science.

A team of UC San Diego researchers and colleagues at Purdue University have now simulated the foundation of new types of artificial intelligence computing devices that mimic brain functions, an achievement that resulted from the COVID-19 pandemic lockdown. By combining new supercomputing materials with specialized oxides, the researchers successfully demonstrated the backbone of networks of circuits and devices that mirror the connectivity of neurons and synapses in biologically based neural networks.

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Ending the global sanitation crisis — jack sim, founder world toilet organization.

Around 2 billion people worldwide still lack access to the basic tools of improved sanitation (toilets and latrines). One billion people still have to defecate in the open, and at least 10% of the world’s population is thought to consume food irrigated by raw wastewater. An estimated 800,000 children, younger than 5 years of age, perish from diarrhea each year, including conditions related to cholera, dysentery, hepatitis A, typhoid and polio.

Mr. Jack Sim is the Founder of the World Toilet Organization (https://www.worldtoilet.org/), an organization established with the aim to break the taboo around toilets and this global sanitation crisis.

Continue reading “Mr. Jack Sim — Founder, World Toilet Organization — Ending The Global Sanitation Crisis” | >

Reducing naturally occurring errors in protein synthesis (production) improves both health and lifespan, finds a new study in simple model organisms led by researchers at UCL and MRC London Institute of Medical Sciences.

The novel findings, published in Cell Metabolism, are the first to demonstrate a direct link between fewer mistakes and longevity.

Explaining the study, lead author Dr. Ivana Bjedov (UCL Cancer Institute), said: We commonly hear about DNA mutations, which can cause cancer, and are considered one of the underlying causes of ageing.

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In contrast to the energy balance model, the carbohydrate-insulin model makes a bold claim: overeating isn’t the main cause of obesity. Instead, the carbohydrate-insulin model lays much of the blame for the current obesity epidemic on modern dietary patterns characterized by excessive consumption of foods with a high glycemic load: in particular, processed, rapidly digestible carbohydrates. These foods cause hormonal responses that fundamentally change our metabolism, driving fat storage, weight gain, and obesity.

Perspective published in The American Journal of Clinical Nutrition argues the root causes of the obesity epidemic are more related to what we eat rather than how much we eat.

Statistics from the Centers for Disease Control and Prevention (CDC) show that obesity affects more than 40% of American adults, placing them at higher risk for heart disease, stroke, type 2 diabetes, and certain types of cancer. The USDA’s Dietary Guidelines for Americans 2020 – 2025 further tells us that losing weight “requires adults to reduce the number of calories they get from foods and beverages and increase the amount expended through physical activity.”

This approach to weight management is based on the century-old energy balance model which states that weight gain is caused by consuming more energy than we expend. In today’s world, surrounded by highly palatable, heavily marketed, cheap processed foods, it’s easy for people to eat more calories than they need, an imbalance that is further exacerbated by today’s sedentary lifestyles. By this thinking, overeating, coupled with insufficient physical activity, is driving the obesity epidemic. On the other hand, despite decades of public health messaging exhorting people to eat less and exercise more, rates of obesity and obesity-related diseases have steadily risen.

Continue reading “Scientists Claim Overeating Is Not the Primary Cause of Obesity — Point to More Effective Weight Loss Strategies” | >

Citicoline, a drug that is naturally found in the body, is commonly used to treat a number of brain injuries and illnesses. For quite some time, doctors have prescribed it for strokes, vascular dementia, Parkinson’s disease, and general aging of the brain. Patients usually see improvement when taking the drug because the body uses it to create and repair cell membranes and lower the presence of free radicals, as noted in the Clinical Interventions in Aging Journal. (Free radicals, which are unstable molecules, can damage cells in the body and are associated with aging and illness.)

Now, researchers from the NYU Grossman School of Medicine have found evidence that citicoline can also be used to treat glaucoma. Normally, glaucoma is treated by removing fluid buildup in the eye, which creates pressure and wears down the cells in the eye and the nerves connecting to the brain. Though monitoring fluid buildup is important, glaucoma can still worsen after the pressure on the eye has been relieved.

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Because the herpesvirus sits in neurons forever, there is speculation it is connected to neurodegenerative diseases. The immune system requires inflammation to constantly fight off the virus, and neurons have some degree of damage because of this continuous immune response, according to Dr. Tibor Valyi-Nagy, professor of pathology, director of neuropathology at UIC and research collaborator on the study.

Summary: Researchers discovered mutations of the OPTN gene resulted in increased herpesvirus 1 growth in the brains of mice, leading to the death of local neurons. This resulted in accelerated neurodegeneration. OPTN deficiency was also associated with impairments in immune response. While these findings are specific to the HSV-1 virus, researchers believe the findings may apply to up to eight herpesvirus infections.

Source: University of Illinois at Chicago

A new study by researchers at University of Illinois Chicago suggests that when the protein optineurin, or OPTN, is present in cells it restricts the spread of HSV-1, the herpes simplex virus type 1.

Continue reading “Study Finds Evidence of Possible Link Between Herpes Simplex and Neurogenerative Diseases” | >

Pollution creates particulate matter (tiny floating particles) and aerosols that can be harmful to our health. With missions like the Multi-Angle Imager for Aerosols (MAIA), public health officials can start to map this particulate matter around the world, understand its effect on diseases, and know where the most risk is. In this month’s talk, we’ll chat with the instrument operations systems engineer for MAIA and discuss how vital positions like hers are for mission success and for making sure important data gets back to us on Earth.

Speaker: janelle wellons, instrument operations systems engineer, NASA/JPL

Host: brian white, public services office, NASA/JPL

Co-host: jocelyn argueta, public outreach specialist, NASA/JPL

Continue reading “Instrumental: Engineers Who Make Science Possible (Live Public Talk)” | >

Britain’s young teens will be vaccinated — but with a single dose.

London: Britain’s chief medical officers have said that vaccinating young teenagers against COVID-19 is justified when their mental health and education are taken into account.

Minors aged between 12 and 15 in England will be offered just a single dose of Pfizer or Moderna beginning next week, with more research ordered into whether a second dose should be given, as is currently administered to those aged 16 and above.

The decision by the CMOs brings the UK partly into line with countries like Australia, the United States, Israel and many European nations including France, which are already offering the jab to minors.

Continue reading “Britain’s young teens will be vaccinated” | >

Automation will drag on at the normal pace. 2025 i think will be the key year, where Human Level hands could turn up on the humanoid robots, and an early phase of Human Level AI turns up; if those 2 things happen automation of jobs will really start to move fast.

Ask for a roast beef sandwich at an Arby’s drive-thru east of Los Angeles and you may be talking to Tori — an artificially intelligent voice assistant that will take your order and send it to the line cooks.

“It doesn’t call sick,” says Amir Siddiqi, whose family installed the AI voice at its Arby’s franchise this year in Ontario, California. “It doesn’t get corona. And the reliability of it is great.”

The pandemic didn’t just threaten Americans’ health when it slammed the U.S. in 2020 — it may also have posed a long-term threat to many of their jobs. Faced with worker shortages and higher labor costs, companies are starting to automate service sector jobs that economists once considered safe, assuming that machines couldn’t easily provide the human contact they believed customers would demand.

Continue reading “Do we need humans for that job? Automation booms after COVID” | >