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The CRISPR craze: genome editing technologies poised to revolutionize medicine and industry

Genome editing by engineered Cas9 systems (credit: Mary Ann Liebert, Inc., publishers) CRISPR/Cas systems for genome editing have revolutionized biological research over the past three years, and their ability to make targeted changes in DNA sequences in living cells with relative ease and affordability is now being applied to clinical medicine and will have a significant impact on advances in drug and other therapies, agriculture, and food products.

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Funding Policies Distort Science

A good summary of the crisis in research and the broken paradigm the medical world is currently stuck in from Josh Mitteldorf’s excellent blog.


Capital shuns risk. — The essence of science is exploration of the unknown. Science and Capitalism is not exactly a match made in heaven. Government and foundation funding has always been behind the curve of innovation, but the recent contraction in US science funding has engendered an unprecedented intensity of competition. This has translated into a disastrous attitude of risk aversion. A “hard-headed” business model prevails at the funding agencies, and they are now funding only those projects that they deem “most likely to succeed.”

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Metal foams found to excel in shielding X-rays, gamma rays, neutron radiation

Lightweight composite metal foams like this one have been found effective at blocking X-rays, gamma rays and neutron radiation, and are capable of absorbing the energy of high impact collisions — holding promise for use in nuclear safety, space exploration, and medical technology applications (credit: Afsaneh Rabiei, North Carolina State University)

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Drug perks up old muscles and aging brains

Irina Conboy is making some amazing advances in aging and rejuvenation research at Berkley. The Conboy lab has been steadily making progress in regenerative medicine and is potentially a few years from having something viable in terms of regenerative medicine. It would be amazing if the community could get behind a single breakthrough project like Irina is working on and making sure this technology arrives soon.

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