Toggle light / dark theme

How calcium may have unlocked the origins of life’s molecular asymmetry

A new study led by researchers at the Earth-Life Science Institute (ELSI) at the Institute of Science, Tokyo, has uncovered a surprising role for calcium in shaping life’s earliest molecular structures. Their findings suggest that calcium ions can selectively influence how primitive polymers form, shedding light on a long-standing mystery: how life’s molecules came to prefer a single “handedness” (chirality).

The study is published in Proceedings of the National Academy of Sciences.

Like our left and right hands, many molecules exist in two mirror-image forms. Yet life on Earth has a striking preference: DNA’s sugars are right-handed, while proteins are built from left-handed . This phenomenon, called homochirality, is essential for life as we know it—but how it first emerged remains a major puzzle in origins of life research.

Hypoxic Preconditioning Enhances the Potential of Mesenchymal Stem Cells to Treat Neonatal Hypoxic-Ischemic Brain Injury

About 20% to 35% of the population suffers from chronic sleep disorders—and up to half of all people in older age. Moreover, almost every teenager or adult has experienced short-term sleep deprivation at some point. There are many reasons for not getting enough sleep, whether it be partying, a long day at work, caring for relatives, or simply whiling away time on smartphones.

In a recent meta-study, Jülich researchers have now been able to show that the involved in the short-term and long-term conditions differ significantly. The results of the study were published in the journal JAMA Psychiatry.

“Poor sleep is one of the most important—but changeable—risk factors for in adolescents and ,” says Jülich researcher and Privatdozent Dr. Masoud Tahmasian, who coordinated the study. In contrast, long-term pathological sleep disorders, such as insomnia, obstructive sleep apnea, narcolepsy, and short-term sleep deprivation, are located in different parts of the brain.

AI Framework Predicts Better Patient Health Care and Reduces Cost

Researchers at Indiana University have shown that an artificial intelligence framework that employs sequential decision-making could reduce healthcare costs by over 50 percent while also improving patient outcomes by over 40 percent. New research from Indiana University has found that machine lea

Brain-computer interface allows paralyzed users to customize their sense of touch

University of Pittsburgh School of Medicine scientists are one step closer to developing a brain-computer interface, or BCI, that allows people with tetraplegia to restore their lost sense of touch.

While exploring a digitally represented object through their artificially created sense of touch, users described the warm fur of a purring cat, the smooth rigid surface of a door key and the cool roundness of an apple. This research, a collaboration between Pitt and the University of Chicago, is published in Nature Communications.

In contrast to earlier experiments where artificial touch often felt like indistinct buzzing or tingling and didn’t vary from object to object, scientists gave BCI users control over the details of the electrical stimulation that creates tactile sensations, rather than making those decisions themselves. This key innovation allowed participants to recreate a sense of touch that felt intuitive to them.

Live human brain tissue reveals how Alzheimer’s-linked protein damages connections

Scientists using living human brain tissue have shown for the first time how a toxic form of a protein linked to Alzheimer’s can stick to and damage the connections between brain cells.

Small pieces of healthy —collected during routine neurosurgery operations—were exposed to the protein, known as amyloid beta.

Unlike when subjected to a normal form of the protein, the brain tissue did not attempt to repair damage caused by the toxic form of amyloid beta, experts say.

Disproportionately Enlarged Subarachnoid-Space Hydrocephalus on MRI in Pathologically Confirmed Progressive Supranuclear Palsy

Background and ObjectiveSeveral studies have shown that idiopathic normal-pressure hydrocephalus (iNPH) can mimic other neurodegenerative disorders, particularly progressive supranuclear palsy (PSP). In this study, we investigated iNPH clinical and…