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Deep RNA sequencing of 164 blood samples collected from long-lived families was performed to investigate the expression patterns of circular RNAs (circRNAs). Unlike that observed in previous studies, circRNA expression in long-lived elderly individuals (98.3 ± 3.4 year) did not exhibit an age-accumulating pattern. Based on weighted circRNA co-expression network analysis, we found that longevous elders specifically gained eight but lost seven conserved circRNA-circRNA co-expression modules (c-CCMs) compared with normal elder controls (spouses of offspring of long-lived individuals, age = 59.3 ± 5.8 year). Further analysis showed that these modules were associated with healthy aging-related pathways. These results together suggest an important role of circRNAs in regulating human lifespan extension.

Virusight Diagnostic, an Israeli company that combines artificial intelligence software and spectral technology announced the results of a study that found that its Pathogens Diagnostic device detects COVID-19 with 96.3 percent accuracy in comparison to the common RT-PCR.

The study was conducted by researchers from the Department of Science and Technology, University of Sannio, Benevento, Italy with partner company TechnoGenetics S.p. A.


The Virusight solution was tested on 550 saliva samples and found to be safe and effective.

Tomatoes gene-edited to produce vitamin D, the sunshine vitamin, could be a simple and sustainable innovation to address a global health problem.

Researchers used gene editing to turn off a specific molecule in the plant’s genome which increased provitamin D3 in both the fruit and leaves of tomato plants. It was then converted to vitamin D3 through exposure to UVB light.

Vitamin D is created in our bodies after skin’s exposure to UVB light, but the major source is food. This new biofortified crop could help millions of people with vitamin D insufficiency, a growing issue linked to higher risk of cancer, dementia, and many leading causes of mortality. Studies have also shown that vitamin D insufficiency is linked to increased severity of infection by Covid-19.

Blockchain technology is spreading like fire across industries and businesses. It is currently used in digital voting, medical recordkeeping, decentralized finance, gaming, capital markets, supply chain management, etc. More and more businesses and individual users want to take advantage of blockchain to increase transparency, security, and communication. To leverage blockchain development in innovative use cases, organizations need to comprehend the programming languages best suited for their upcoming projects. Here are the top 5 hottest blockchain programming languages that are being utilized by start-ups and enterprises today.

A high-level programming language is getting more popularity as a blockchain developer language, particularly for dApps development. If you are looking for a language for developing smart contracts on Ethereum Blockchain, Solidity is the one. It is a contract-based language, allowing to store all the logic in the code of the Blockchain.

With amazing code portability, it is the most popular programming language among application developers. It has been used to create smart contracts such as Truffle, ARK, and some of the popular blockchains that are developed using Java include Ethereum, IOTA, NEM, and NEO.

Our bodies are pretty ingenious when it comes to self-repair, and scientists have been studying in detail the ways in which the heart patches itself up after a heart attack (myocardial infarction). They hope to find clues that could lead to better treatments for cardiovascular problems.

New research has revealed that the immune response of the body and the lymphatic system (part of the immune system) are crucial in the way that the heart repairs itself after a heart attack has caused damage to the heart muscle.

Key to the study was the discovery of the role played by macrophages, specialist cells that can destroy bacteria or initiate helpful inflammation responses. As the first responders on a scene after a heart attack, these macrophages produce a particular type of protein called VEGFC, the researchers report.

Researchers at the Technical University of Munich (TUM) have developed a film that not only protects wounds similar to the way a bandage does, but also helps wounds to heal faster, repels bacteria, dampens inflammation, releases active pharmaceutical ingredients in a targeted manner and ultimately dissolves by itself. This is all made possible by its dedicated design and the use of mucins, molecules which occur naturally in mucous membranes.

Conventional bandages may be very effective for treating smaller skin abrasions, but things get more difficult when it comes to soft-tissue injuries such as on the tongue or on sensitive surfaces like the intestines. What kind of material will adhere there without damaging the tissue or sticking to adjacent points? How can wounds be protected from external influences and bacteria? What kind of substance will allow cells underneath to close the wound, and then ultimately disappear without a trace?

In spite of recent progress in developing materials addressing some of the specific requirements mentioned above, engineering a multifunctional all-in-one solution remains a challenge. A team led by Oliver Lieleg, Professor of Biomechanics at the Technical University of Munich (TUM), has developed a biopolymer film that combines a wide range of different functions at the same time. In a recently published study, the biomolecular “bandage” showed highly promising results and is ready to undergo further testing and tailoring.

Lack of a robotic hand that can match a human hand will continue to delay full automation.


SINGAPORE, May 30 (Reuters) — After struggling to find staff during the pandemic, businesses in Singapore have increasingly turned to deploying robots to help carry out a range of tasks, from surveying construction sites to scanning library bookshelves.

The city-state relies on foreign workers, but their number fell by 235,700 between December 2019 and September 2021, according to the manpower ministry, which notes how COVID-19 curbs have sped up “the pace of technology adoption and automation” by companies.

At a Singapore construction site, a four-legged robot called “Spot”, built by U.S. company Boston Dynamics, scans sections of mud and gravel to check on work progress, with data fed back to construction company Gammon’s control room.

This just came out, a day or so ago.


Can the aging process be reversed — or even halted, altogether? If we manage to decode this final mystery of our human biology, we might soon be able to eradicate age-related illnesses like cancer, dementia and heart problems.

The race to invent the miracle pill is well underway. Today, international researchers are getting astonishingly close to realizing humanity’s dream of immortality.

The hunt for immortality gained traction with the discovery of Costa Rica’s so-called “Blue Zone, by Luis Rosero-Bixby. In the “Blue Zone, on the Nicoya Peninsular, he found a remarkable number of centenarians. Here, male life expectancy is the highest in the world. Their healthy lifestyle is one factor, but the promise of longevity is probably also because their telomeres — sections of DNA found at the end of chromosomes — are longer than those of the average person.

It’s a field of research currently being explored by Maria Blasco in Madrid. But this is just one of many possible factors influencing the process of aging. Senescent cells may also play a key role. Also known as “zombie cells, these attack our body in old age and flood it with alarm signals until, at some point, we collapse under their weight. That’s a theory proposed by another researcher in Spain, Manuel Serrano.

Just as it’s hard to understand a conversation without knowing its context, it can be difficult for biologists to grasp the significance of gene expression without knowing a cell’s environment. To solve that problem, researchers at Princeton Engineering have developed a method to elucidate a cell’s surroundings so that biologists can make more meaning of gene expression information.

The researchers, led by Professor of Computer Science Ben Raphael, hope the new system will open the door to identifying rare cell types and choosing cancer treatment options with new precision. Raphael is the senior author of a paper describing the method published May 16 in Nature Methods.

The basic technique of linking with a cell’s environment, called spatial transcriptomics (ST), has been around for several years. Scientists break down onto a microscale grid and link each spot on the grid with information about gene expression. The problem is that current computational tools can only analyze spatial patterns of gene expression in two dimensions. Experiments that use multiple slices from a single tissue sample—such as a region of a brain, heart or tumor—are difficult to synthesize into a complete picture of the cell types in the tissue.