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Category: biotech/medical – Page 1,140

The researchers wanted to create robots that could pick up and sort molecules within a designated space. This makes it possible for DNA molecules to serve as the building blocks for 3D nanostructures that self-assemble in a predetermined shape. Tiny DNA-based robots and other nanodevices will deliver medicine inside our bodies, detect the presence of deadly pathogens, and help manufacture increasingly smaller electronics.

This enabled the researchers to design a nano-robot composed of three DNA origami structures. To help it maneuver within the designated space, the robot had a “leg” with a pair of feet. An “arm” with a “hand” allowed it to carry cargo, and a third component was added to tell the hand when a specific drop-off point had been reached so it would know to release the cargo. It allows researchers to carry out the entire design truly in 3D. Earlier design tools only allowed creation in 2D, forcing researchers to map their creations into 3D.

The software helps researchers design ways to take tiny strands of DNA and combine them into complex structures with parts like rotors and hinges that can move and complete a variety of tasks, including drug delivery. The robot will also enable researchers to more precisely determine important signaling pathways for a variety of biological and pathological processes that are stimulated at the cellular level during the application of force.

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Holographic teleportation could solve the many issues that 2D virtual meetings have these days. Besides, you could simply beam into work while at home.

Researchers at the University of Western Ontario recently completed the world’s first-ever international holographic teleportation.

The coronavirus pandemic pushed the digitalization of many day-to-day functions of our lives. An important one among them was meeting people. Instead of having to commute to the office or travel across the oceans for a meeting, one could simply connect via an online video call and get the work done.

Even after two years, virtual meetings haven’t been able to completely replicate the ease of an in-person meeting, something that researchers are hoping holographic teleportation can solve. A combination of hologram and teleport, the technology is fondly called holoport and allows one to instantly beam the hologram of a person to a far-off location, much like the Star Trek universe.

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A new experimental drug for cancer was discovered to foster nerve regeneration after spinal trauma.

𝙎𝙘𝙞𝙚𝙣𝙩𝙞𝙨𝙩𝙨 𝙛𝙧𝙤𝙢 𝙩𝙝𝙚 𝙐𝙣𝙞𝙫𝙚𝙧𝙨𝙞𝙩𝙮 𝙤𝙛 𝘽𝙞𝙧𝙢𝙞𝙣𝙜𝙝𝙖𝙢 𝙝𝙖𝙫𝙚 𝙨𝙝𝙤𝙬𝙣 𝙩𝙝𝙖𝙩 𝙖 𝙗𝙧𝙖𝙞𝙣-𝙥𝙚𝙣𝙚𝙩𝙧𝙖𝙩𝙞𝙣𝙜 𝙘𝙖𝙣…

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Researchers from Santa Clara University, New Jersey Institute of Technology and the University of Hong Kong have been able to successfully teach microrobots how to swim via deep reinforcement learning, marking a substantial leap in the progression of microswimming capability.

There has been tremendous interest in developing artificial microswimmers that can navigate the world similarly to naturally-occuring swimming microorganisms, like bacteria. Such microswimmers provide promise for a vast array of future biomedical applications, such as targeted drug delivery and microsurgery. Yet, most artificial microswimmers to date can only perform relatively simple maneuvers with fixed locomotory gaits.

The artificial intelligence-powered swimmer switches between different modes of locomotory gaits (color-coded) autonomously in tracing a complex trajectory ‘SWIM’. (Image: Commun. Phys., 5,158 (2022))

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New York’s Gorbunova Aging Research Center team is encouraged by frailty results from SIRT6 activator trial.

SIRT6, the so-called “longevity sirtuin” has been making rather a name for itself.

SIRT6 is a protein with an important job. It is vital for both normal base excision repair and double-strand break repair of DNA damage – damage that can lead to genomic instability, which ultimately contributing to aging. These repairs decline with age but can be boosted with SIRT6 [1].

But SIRT6 has another string to its longevity bow; back in 2019, Vera Gorbunova, professor of biology at the University of Rochester, and her team, demonstrated an overexpression of SIRT6 protein leads to extended lifespan. The researchers also showed that the opposite is also true – a deficiency in SIRT6 can cause premature aging [2].

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MPXV was first discovered during a nonfatal outbreak at an animal facility in Copenhagen, Denmark, in 1958. The facility received a continual supply of Asian monkeys (mostly M. fascicularis) and rhesus macaques (Macaca mulatta), which were used for polio vaccine research. The first outbreak occurred 2 months after the monkeys had been received and the second outbreak occurred 4 months after the initial outbreak. The outbreaks occurred in M. fascicularis that had arrived from Singapore. Upon arrival, monkeys were treated with antibiotics and appeared in satisfactory health.

Monkeypox virus (MPXV) was discovered in 1958 during an outbreak in an animal facility in Copenhagen, Denmark. Since its discovery, MPXV has revealed a propensity to infect and induce disease in a large number of animals within the mammalia class from pan-geographical locations. This finding has impeded the elucidation of the natural host, although the strongest candidates are African squirrels and/or other rodents. Experimentally, MPXV can infect animals via a variety of multiple different inoculation routes; however, the natural route of transmission is unknown and is likely to be somewhat species specific. In this review we have attempted to compile and discuss all published articles that describe experimental or natural infections with MPXV, dating from the initial discovery of the virus through to the year 2012. We further discuss the comparative disease courses and pathologies of the host species.

Keywords: aerosol, animals, infection, intrabronchial, intradermal, intramuscular, intranasal, intratracheal, intravenous, outbreak, primates, subcutaneous.

Orthopoxviruses (OPVs) have host specificities ranging from narrow (e.g., ectromelia and variola [VARV]) to broad (e.g., cowpox and vaccinia [VACV]). Monkeypox virus (MPXV) has a broad host-range and is capable of infecting many species from across the globe. In nature, the major environs of MPXV are restricted to the Congo Basin (CB) and West Africa (WA). The MPXV virion is a brick-shaped enveloped virus of 200–250 nm, characterized by surface tubules and a dumbbell-shaped core. Humans and highly susceptible nonhuman primates (NHPs) infected with MPXV have near identical clinical manifestations compared to humans infected with VARV. For humans, the only obvious difference in clinical signs is the absence of lymphadenopathy in smallpox patients [1,2].

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As most of you know I have cancer called multiple myeloma and have had it for almost a decade now. Unfortunately medical bills are staggering, especially in the US. I am asking to reach a goal of $10,000 to help wipe out if not most of my medical debt and expenses. I have over 1,000 friends on Facebook. If each friend donated $8.00 this would help me not only reach but exceed my goal. Please consider helping:

If anyone needs proof of my diagnosis or medical debt please message me.

I have outlined my journey with cancer several years ago on Lifeboat Foundation’s blog: https://lifeboat.com/blog/2018/09/83169

Hi, my name is Nicholas and I was diagnosed with multiple myeloma several years ago. Medical bills are exceedingly expensive even with insurance. I am creating content on tiktok in hopes to create an income to help me cover such costs.

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