Toggle light / dark theme

New technology maps where and how cells read their genome

A new study published in Nature reports that a technology known as spatial omics can be used to map simultaneously how genes are switched on and off and how they are expressed in different areas of tissues and organs. This improved technology, developed by researchers at Yale University and Karolinska Institutet, could shed light on the development of tissues, as well as on certain diseases and how to treat them.

Almost all cells in the body have the same set of genes and can in principle become any kind of cell. What distinguishes the cells is how the genes in our DNA are used. In recent years, spatial omics have given us a deeper understanding of how cells read the genome in precise locations in tissues. Now, researchers have further evolved this technology to increase knowledge of how tissues develop and how different diseases arise.

A key part of the study is the researchers’ ability to spatially map simultaneously two crucial components of our genetic makeup, the epigenome and the . The epigenome controls the switching mechanisms that turn genes on and off in individual , whereas the transcriptome is the result of those gene expressions and what makes each cell unique.

Study finds mushrooms magnify memory

Researchers from The University of Queensland have discovered the active compound from an edible mushroom that boosts nerve growth and enhances memory.

Professor Frederic Meunier from the Queensland Brain Institute said the team had identified new active compounds from the mushroom, Hericium erinaceus.

“Extracts from these so-called ‘lion’s mane’ mushrooms have been used in in Asian countries for centuries, but we wanted to scientifically determine their on ,” Professor Meunier said.

SpaceX’s Dragon set to deliver beating human heart tissue to the ISS

Long-term microgravity exposure causes various biological changes, ranging from bone loss to changes in cardiovascular function.

Towards this, SpaceX’s Dragon cargo ship is set to deliver cardiac tissue chips to the International Space Station (ISS). According to NASA, the cargo spacecraft is expected to autonomously dock with the ISS at 7:52 am EDT Thursday, March 16.

Scientists discover key information about the function of mitochondria in cancer cells

Scientists have long known that mitochondria play a crucial role in the metabolism and energy production of cancer cells. However, until now, little was known about the relationship between the structural organization of mitochondrial networks and their functional bioenergetic activity at the level of whole tumors.

In a new study, published in Nature, researchers from the UCLA Jonsson Comprehensive Cancer Center used (PET) in combination with to generate 3-dimensional ultra-resolution maps of mitochondrial networks in of genetically engineered mice.

They categorized the tumors based on mitochondrial activity and other factors using an artificial intelligence technique called , quantifying the mitochondrial architecture across hundreds of cells and thousands of mitochondria throughout the tumor.

DNA synthesis technologies to close the gene writing gap

NPL, in collaboration with London Biofoundry and BiologIC Technologies Ltd, have released an analysis on existing and emerging DNA Synthesis technologies in Nature Reviews Chemistry, featuring the work on the front cover.

The study, which was initiated by DSTL, set out to understand the development trajectory of DNA Synthesis as a major industry drive for the UK economy over the next 10 years. The demand for synthetic DNA is growing exponentially. However, our ability to make, or write, DNA lags behind our ability to sequence, or read, it. The study reviewed existing and emerging DNA synthesis technologies developed to close this gene writing gap.

DNA or genes provide a universal tool to engineer and manipulate living systems. Recent progress in DNA synthesis has brought up limitless possibilities in a variety of industry sectors. Engineering biology, therapy and diagnostics, , defense and nanotechnology are all set for unprecedented breakthroughs if DNA can be provided at scale and low cost.

A 53-year-old longevity researcher says his ‘biological age’ is a decade younger thanks to 4 daily habits — but the science behind them is mixed

“That’s got molecules in it that will prevent cancer, among other things” like anti-inflammatory properties, he said. Some older research has shown, for example, that green tea consumption might be linked to a lower risk of stomach cancer.

Sinclair also said he takes supplements (like those sold on the Tally Health website) that contain resveratrol, which his team’s research has shown can extend the lifespan of organisms like yeast and worms.

While the compound, famously found in red wine, is known to have anti-inflammatory, anti-cancer, heart health, and brain health benefits, the research is mixed on if or how well such benefits can be achieved in humans through a pill.

The Top 5 Science Fiction Books That Explore the Ethics of Cloning

FallenKingdomReads’ list of The Top 5 Science Fiction Books That Explore the Ethics of Cloning.

Cloning is a topic that has been explored in science fiction for many years, often raising questions about the ethics of creating new life forms. While the idea of cloning has been discussed in various forms of media, such as movies and TV shows, some of the most interesting and thought-provoking discussions on the topic can be found in books. Here are the top 5 science fiction books that explore the ethics of cloning.

Alastair Reynolds’ House of Suns is a space opera that explores the ethics of cloning on a grand scale. The book follows the journey of a group of cloned human beings known as “shatterlings” who travel the galaxy and interact with various other sentient beings. The book raises questions about the nature of identity and the value of individuality, as the shatterlings face challenges that force them to confront their own existence and the choices they have made.

/* */