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Category: biotech/medical – Page 1,052

Lung cancer is the third most common cancer in the United States, following skin and breast cancers– with over two hundred and thirty-six thousand cases diagnosed in 2022 alone, according to the American Cancer Society. The most significant risk factor includes smoking, with eighty to ninety percent of all lung cancer deaths being linked to smoking in the U.S. Other contributing factors include secondhand smoke, the inhalation of radon– a naturally occurring gas– and familial history of lung cancer.

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Leprosy is a chronic infectious disease caused by the bacterium Mycobacterium leprae. It affects the skin, nerves, and mucous membranes, and can lead to severe disfigurement and disability if left untreated.

Leprosy, a chronic infectious disease caused by the bacterium Mycobacterium leprae, is one of the oldest and most persistent diseases in the world. However, new surprising research suggests that the bacteria that cause leprosy may also have the ability to stimulate the growth and regeneration of the liver in adult animals without causing damage or scarring. Scientists have discovered that parasites associated with leprosy can reprogram cells to increase the size of the liver.

The findings suggest the potential to use this natural process to rejuvenate aging livers and extend the period of disease-free living in humans, known as healthspan. It may also be possible to use this process to regenerate damaged livers, potentially reducing the need for liver transplantation, which is currently the only effective treatment for individuals with severely scarred livers.

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Nobel winner Jennifer Doudna explains CRISPR, the gene-editing technology she pioneered.

Berkeley scientist Jennifer Doudna won the 2020 Nobel Prize for her work on the revolutionary gene-editing technology known as CRISPR. It has the potential to cure genetic diseases like sickle cell anemia and hereditary blindness and may even be used to treat cancer and HIV. But when it comes to editing humanity, where do we draw the line? How do we avoid falling into the same kind of dystopian nightmare outlined in Blade Runner? Doudna discussed the risks and benefits of CRISPR in an interview with Ian Bremmer on GZERO World. Also in this episode: a look at cloning our pets (speaking of going too far…).

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Continue reading “Applying CRISPR Tech to Edit the Code of Life | Dr. Jennifer Doudna | GZERO World with Ian Bremmer” | >

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There are fossils of viruses, of sorts, preserved in the DNA of the hosts that they’ve infected. Including you. This molecular fossil trail can help us understand where viruses came from, how they evolved and it can even help us tackle the biggest question of all: Are viruses alive?

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The researchers conducted a deep dive into the genetics of these tumours, both during the slow chronic phase and after the disease had transformed into the aggressive form. Researchers have identified an important transition point in the shift from chronic to aggressive blood cancer by conducting experiments in mice, providing a new intervention point for hampering the progress of the disease, according to a study.

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Orally administered collagen peptides could contribute to antiaging by replacing the degraded extracellular matrix proteins caused by photoaging. This study aimed to evaluate the efficacy and safety of low-molecular-weight collagen peptides for treating photoaged and dry skin. In this randomized, placebo-controlled, parallel-group, double-blinded trial, we randomly assigned study participants (n = 100) to either the test product group or placebo group at a 1:1 ratio for 12 weeks. The wrinkle scale score, eye wrinkle volume, roughness parameters, such as the average maximum height of the wrinkle (Rz), arithmetic average within the total measuring length of the wrinkle (Ra), maximum profile valley depth of the wrinkle (Rv), and skin hydration, transepidermal water loss (TEWL), overall elasticity (R2), and ratio of elastic recovery to total deformation (R7) were evaluated at baseline, 6 weeks, and 12 weeks. Safety assessments with serial blood tests were also conducted. Efficacy assessments of data from 84 participants were conducted as the per-protocol analysis. After 12 weeks, the 10-grade crow’s feet photo scale score, eye wrinkle volume, skin roughness parameters (Rz, Ra, and Rv), skin elasticity (R2 and R7), skin hydration, and TEWL were significantly improved in the test product group compared to the placebo group. There were no adverse events or abnormalities according to laboratory analysis associated with using the test material during the study period. This study showed that the oral supplementation of low-molecular-weight collagen peptides could improve the wrinkles, elasticity, hydration, and barrier integrity of photoaged facial skin. This clinical study was registered with the Korean Clinical Research Information Service and International Clinical Trials Registry Platform (No: KCT0006500).

Keywords: clinical study; collagen peptide; photoaging; wrinkles.

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