Summary: Blocking the activity of the reactor called the aryl hydrocarbon receptor in T cells resulted in both a decrease in inflammation and recovery in mouse models of multiple sclerosis.
Source: University of Virginia.
University of Virginia Health neuroscientists have discovered a potential way to disrupt the chronic inflammation responsible for multiple sclerosis.
Immunotherapy is currently a treatment option for breast cancer, melanoma, leukemia, and non-small cell lung cancer.
Researchers are currently looking at using immunotherapy as a treatment for other types of cancer, including prostate cancer, brain cancer, and ovarian cancer.
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Our DNA holds thousands of dead genes and we’ve only just begun to unravel their stories. But one thing is already clear: we’re not just defined by the genes that we’ve gained over the course of our evolution, but also by the genes that we’ve lost along the way.
Thanks to these illustrators for their wonderful hominin illustrations featured throughout this episode!
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This video features this Paleogeographic Map: Scotese, C.R., 2019. Plate Tectonics, Paleogeography, and Ice Ages, YouTube video: https://youtu.be/UevnAq1MTVA.
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This process is no less relevant to humans than any other species in nature, but since our species is such an evolutionary newcomer, the extent of its influence — and how it might work today — is still difficult to pin down.
The challenge: A team of researchers in Greece and Ireland, led by Nikolaos Vakirlis at the Alexander Fleming Biomedical Sciences Research Center in Athens, argues that a key to understanding human evolution lies with short sequences of DNA named “open reading frames” (ORFs). These structures are small sections of the genome that encode tiny protein molecules — microproteins — which can perform a diverse range of crucial biological tasks, from regulating muscle performance to alerting cells to damaging stresses.
Due to their minuscule sizes, ORFs are notoriously difficult to study. Because of this, their full relevance has gone under the radar in mainstream genomics research until recently, and even today, they still aren’t considered to be proper genes in themselves. For Vakirlis’ team, this potential oversight masks the fact that the microproteins encoded by ORFs can develop their own de novo sequences over generations, which may eventually develop into new genes.
The Johns Hopkins Center for Health Security, in partnership with WHO and the Bill & Melinda Gates Foundation, conducted Catastrophic Contagion, a pandemic tabletop exercise at the Grand Challenges Annual Meeting in Brussels, Belgium, on October 23, 2022.
The extraordinary group of participants consisted of 10 current and former Health Ministers and senior public health officials from Senegal, Rwanda, Nigeria, Angola, Liberia, Singapore, India, Germany, as well as Bill Gates, co-chair of the Bill & Melinda Gates Foundation.
The exercise simulated a series of WHO emergency health advisory board meetings addressing a fictional pandemic set in the near future. Participants grappled with how to respond to an epidemic located in one part of the world that then spread rapidly, becoming a pandemic with a higher fatality rate than COVID-19 and disproportionately affecting children and young people.
A couple minutes of your time for a little optimism.
Dr David Sinclair talks about no matter all the push backs and criticizes, he believes reverse aging therapy for human will be succeeded in this short clip.
David Sinclair is a professor in the Department of Genetics and co-director of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School, where he and his colleagues study sirtuins—protein-modifying enzymes that respond to changing NAD+ levels and to caloric restriction—as well as chromatin, energy metabolism, mitochondria, learning and memory, neurodegeneration, cancer, and cellular reprogramming.
Dr David Sinclair has suggested that aging is a disease—and that we may soon have the tools to put it into remission—and he has called for greater international attention to the social, economic and political and benefits of a world in which billions of people can live much longer and much healthier lives.
Dr David Sinclair is the co-founder of several biotechnology companies (Life Biosciences, Sirtris, Genocea, Cohbar, MetroBiotech, ArcBio, Liberty Biosecurity) and is on the boards of several others.
Posted in biotech/medical, business, economics, education, food, health, media & arts, policy
In collaboration with the UC San Diego Center for Integrative Nutrition, the Berry Good Food Foundation convenes a panel of experts to discuss the rise of comprehensive medicine and nutritional healing to treat chronic disease and maintain general well-being. [6/2018] [Show ID: 33486]
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Neurologists at a memory clinic in China have diagnosed a 19-year-old with what they believe to be Alzheimer’s disease, making him the youngest person to be diagnosed with the condition in the world.
The male teenager began experiencing memory decline around age 17, and the cognitive losses only worsened over the years.
Imaging of the patient’s brain showed shrinkage in the hippocampus, which is involved in memory, and his cerebrospinal fluid hinted at common markers of this most common form of dementia.
00:00 Intro.
01:01 ChatGPT x Neuralink.
16:45 Inserting stents into blood vessels.
26:48 Pros & Cons of Neuralink’s architecture.
31:55 Neuralink clinics.
33:51 Downloading our minds onto a Tesla Optimus Bot.
52:30 If you get a Neuralink, will you lose free will?
1:04:16 AI helping Neuralink.
1:09:55 Everyone’s brain is unique.
1:23:16 Getting a Neuralink as a baby.
1:25:20 Sleep paralysis.
1:30:01 Nanotechnology x Neuralink.
1:31:59 James has an idea for Neuralink.
1:46:22 James’ favorite answer to the Fermi Paradox.
1:55:08 Haha smile
Neura Pod is a series covering topics related to Neuralink, Inc. Topics such as brain-machine interfaces, brain injuries, and artificial intelligence will be explored. Host Ryan Tanaka synthesizes informationopinions, and conducts interviews to easily learn about Neuralink and its future.
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Support: https://www.patreon.com/neurapod/
Please consider supporting by joining the channel above, or sharing my other company website with retirees: https://www.reterns.com/. Opinions are my own. Neura Pod receives no compensation from Neuralink and has no affiliation to the company.
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A baby with a rare inherited disorder became the first child in the U.K. to receive a new gene therapy for the condition.
