Lifeboat Foundation

High-Risk, High-Payoff Bio-Research For National Security Challenges — Dr. David A. Markowitz, Ph.D., IARPA

Dr. David A. Markowitz, Ph.D. (https://www.markowitz.bio/) is a Program Manager at the Intelligence Advanced Research Projects Activity (IARPA — https://www.iarpa.gov/) which is an organization that invests in high-risk, high-payoff research programs to tackle some of the most difficult challenges of the agencies and disciplines in the U.S. Intelligence Community (IC).

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Harvard University geneticist Dr. David Sinclair’s lab is developing a cheek swab test kit so that you can check your biological age at home. You then get updates on how to slow down and reverse your aging.

Find out how fast you’re aging with Tally Health. The future of healthy aging is here.

Messenger RNA

#biology #biochemistry #rna

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https://www.youtube.com/watch?v=5eVyphsl0x0

Where does the mind end and the world begin? Is the mind locked inside its skull, sealed in with skin, or does it expand outward, merging with things and places and other minds that it thinks with? What if there are objects outside—a pen and paper, a phone—that serve the same function as parts of the brain, enabling it to calculate or remember?

In their famous 1998 paper “The Extended Mind,” philosophers Andy Clark and David J. Chalmers posed those questions and answered them provocatively: cognitive processes “ain’t all in the head.” The environment has an active role in driving cognition; cognition is sometimes made up of neural, bodily, and environmental processes.

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Vanadium dioxide is a strange material that “remembers” information and when it was stored. This is akin to biological memory.

Summary: A new study will investigate the genetic and biological mysteries of extreme longevity and healthy aging.

Source: american federation for aging research.

Decades of research will be aided by the results of a study launched today – the most ambitious ever conducted to uncover and understand the genetic and biological mysteries of exceptional longevity and healthy aging.

Ancient bacteria might be sleeping beneath the surface of Mars, where it has been shielded from the harsh radiation of space for millions of years, according to new research.

While no evidence of life has been found on the red planet, researchers simulated conditions on Mars in a lab to see how bacteria and fungi could survive. The scientists were surprised to discover that bacteria could likely survive for 280 million years if it was buried and protected from the ionizing radiation and solar particles that bombard the Martian surface.

The findings suggested that if life ever existed on Mars, the dormant evidence of it might still be located in the planet’s subsurface — a place that future missions could explore as they drill into Martian soil.

The first recorded brain activity of a person during their death suggests a biological trigger for near-death experiences.

Synthetic biology offers a way to engineer cells to perform novel functions, such as glowing with fluorescent light when they detect a certain chemical. Usually, this is done by altering cells so they express genes that can be triggered by a certain input.

However, there is often a long lag time between an event such as detecting a molecule and the resulting output, because of the time required for cells to transcribe and translate the necessary genes. MIT synthetic biologists have now developed an alternative approach to designing such circuits, which relies exclusively on fast, reversible protein-protein interactions. This means that there’s no waiting for genes to be transcribed or translated into proteins, so circuits can be turned on much faster—within seconds.

“We now have a methodology for designing protein interactions that occur at a very fast timescale, which no one has been able to develop systematically. We’re getting to the point of being able to engineer any function at timescales of a few seconds or less,” says Deepak Mishra, a research associate in MIT’s Department of Biological Engineering and the lead author of the new study.